Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

Journal of Biological Chemistry

Volumn 278, Issue 21, 2003, Pages 19367-19377

  Holtz, William Andrew ^b   O'Malley, Karen Laurel ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETIC MATERIALS; DISEASES; GENES; RNA;

OXIDATIVE STRESSES;

PROTEINS;

1 METHYL 4 PHENYLPYRIDINIUM; CHAPERONE; CYCLOHEXIMIDE; DOPAMINE; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2; NEUROTOXIN; OXIDOPAMINE; PROTEASOME; PROTEIN C JUN; PROTEIN PERK; RNA; UBIQUITIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; CASPASE; CCAAT ENHANCER BINDING PROTEIN; CYSTEINE PROTEINASE; DNA BINDING PROTEIN; DOPAMINE, GLY PRO AMIDE; DOPAMINE, GLY-PRO-AMIDE-; DRUG DERIVATIVE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; MESSENGER RNA; MOLECULAR CHAPERONE GRP78; MULTIENZYME COMPLEX; PERK KINASE; PHOSPHORUS DERIVATIVE; PHOSPHORUS OXYCHLORIDE; PROTEIN KINASE R; TRANSCRIPTION FACTOR; X BOX BINDING PROTEIN (RF X); X BOX BINDING PROTEIN (RF-X);

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA MICROARRAY; DOPAMINERGIC NERVE CELL; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME INACTIVATION; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARKINSONISM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE DIAGNOSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; STATISTICAL SIGNIFICANCE; TRANSCRIPTION REGULATION; WESTERN BLOTTING; CELL CULTURE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; METABOLISM; NERVE CELL; PARKINSON DISEASE; PHYSIOLOGY;

ANIMALIA; PARKINSONIA;

1-METHYL-4-PHENYLPYRIDINIUM; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASES; CCAAT-ENHANCER-BINDING PROTEINS; CELL DEATH; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; DOPAMINE; EIF-2 KINASE; EMBRYO; ENDOPLASMIC RETICULUM; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; MOLECULAR CHAPERONES; MULTIENZYME COMPLEXES; NEURONS; OXIDOPAMINE; PARKINSON DISEASE, SECONDARY; PHOSPHORUS COMPOUNDS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; PROTO-ONCOGENE PROTEINS C-JUN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; UBIQUITIN;

EID: 0038143287     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211821200     Document Type: Article

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