Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells

Human Molecular Genetics

Volumn 14, Issue 24, 2005, Pages 3787-3799

  Schoenfeld, Robert A ^a   Napoli, Eleonora ^a   Wong, Alice ^a   Zhan, Shan ^a   Reutenauer, Laurence ^d   Morin, Dexter ^a   Buckpitt, Alan R ^a   Taroni, Franco ^a   Lonnerdal, Bo ^b   Ristow, Michael ^c   Puccio, Hélène ^d   Cortopassi, Gino A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Instituto Nazionale   (Italy)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; COPROPORPHYRINOGEN OXIDASE; CYTOCHROME C OXIDASE; FERROCHELATASE; FRATAXIN; HEME; IRON; PROTOPORPHYRIN; RNA; TRANSCRIPTOME; ZINC;

ANIMAL CELL; ARTICLE; DOWN REGULATION; ENZYME ACTIVITY; FRIEDREICH ATAXIA; GENETIC TRANSCRIPTION; HEART; HEART MUSCLE CELL; HUMAN; HUMAN CELL; LIVER; MAMMAL CELL; METABOLITE; MITOCHONDRION; NERVE DEGENERATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEFICIENCY; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE MICROARRAY; UPREGULATION;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; COPROPORPHYRINOGEN OXIDASE; CYTOCHROMES C; FERROCHELATASE; HEART; HEME; HUMANS; IRON-BINDING PROTEINS; MAMMALS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTATION; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS; PROTOPORPHYRINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC; ZINC;

ANIMALIA; ATAXIA; MAMMALIA; MURINAE;

EID: 29644442275     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi393     Document Type: Article

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