IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin

Journal of Clinical Investigation

Volumn 113, Issue 9, 2004, Pages 1271-1276

  Nemeth, Elizabeta ^a   Rivera, Seth ^a   Gabayan, Victoria ^a   Keller, Charlotte ^b   Taudorf, Sarah ^b   Pedersen, Bente K ^b   Ganz, Tomas ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HEPCIDIN; INTERLEUKIN 6; IRON; LIPOPOLYSACCHARIDE; ANTIMICROBIAL CATIONIC PEPTIDE; MESSENGER RNA;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION; INFLAMMATION; INFLAMMATORY DISEASE; IRON BLOOD LEVEL; IRON DEFICIENCY ANEMIA; IRON INTAKE; LIVER; LIVER CELL CULTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VOLUNTEER; ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL CULTURE; CELL LINE; COMPARATIVE STUDY; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; IRON METABOLISM DISORDER; KUPFFER CELL; LIVER CELL; METABOLISM; MONOCYTE; MOUSE MUTANT; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URINE;

ANEMIA; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; CELL LINE; CELLS, CULTURED; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; INFLAMMATION; INTERLEUKIN-6; IRON; IRON METABOLISM DISORDERS; KUPFFER CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MONOCYTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 2342510407     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200420945     Document Type: Article

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