Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress

Molecular and Cellular Biology

Volumn 20, Issue 16, 2000, Pages 5818-5827

  Tsuji, Y ^a   Ayaki, H ^a   Whitman, S P ^a   Morrow, C S ^a   Torti, S V ^a   Torti, F M ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; GENE ACTIVATION; GENE STRUCTURE; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RNA BINDING; RNA TRANSLATION; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; CELL LINE; FERRITINS; MICE; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; PROTEIN BIOSYNTHESIS; TRANSCRIPTION, GENETIC;

ANIMALIA; EUKARYOTA;

EID: 0033853838     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.16.5818-5827.2000     Document Type: Article

References (48)

1. Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer
2. Induction of ferritin synthesis by oxidative stress. Transcriptional and post-transcriptional regulation by expansion of the 'free' iron pool
3. Regulation of ferritin synthesis in malignant and non-malignant lymphoid cells
4. Tumor cell heme uptake induces ferritin synthesis resulting in altered oxidant sensitivity: Possible role in chemotherapy efficacy
5. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements
6. Transcriptional regulation of the rat NAD(P)H:quinone reductase gene. Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants
7. Two adjacent AP-1-like binding sites form the electrophile-responsive element of the murine glutathione S-transferase Ya subunit gene
8. Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch
9. Cytosol and serum ferritin in breast carcinoma
10. The ferritins: Molecular properties, iron storage function and cellular regulation
11. A model for the structure and functions of iron-responsive elements
12. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
13. Free radicals in disease
14. Antioxidant response element
15. Loops and bulge/loops in iron-responsive element isoforms influence iron regulatory protein binding. Fine-tuning of mRNA regulation?
16. Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha
17. Murine ferritin heavy chain: Isolation and characterization of a functional gene
18. Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy-and light-subunit mRNAs
19. Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element
20. Cancer risk and oxidative DNA damage in man
21. Oxidative stress induces activation of a cytosolic protein responsible for control of iron uptake
22. Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates
23. Constitutive and beta-naphthoflavone-induced expression of the human gammaglutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence
24. Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene
25. Adenovirus E1A blocks oxidant-dependent ferritin induction and sensitizes cells to pro-oxidant cytotoxicity
26. Rapid responses to oxidative stress mediated by iron regulatory protein
27. Activation of iron regulatory protein-1 by oxidative stress in vitro
28. Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress
29. 2) control mammalian iron metabolism by different pathways
30. Role of ferritin in the control of the labile iron pool in murine erythroleukemia cells
31. Chemical and molecular regulation of enzymes that detoxify carcinogens
32. Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones
33. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA
34. Aryl hydrocarbon receptormediated signal transduction
35. Role of H and L subunits in mouse ferritin
36. The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
37. Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants
38. The role of iron in oxygen-mediated toxicities
39. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
40. The ferritin family of iron storage proteins
41. The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factorinducible gene
42. FER-1, an enhancer of the ferritin H gene and a target of E1A-mediated transcriptional repression
43. Tumor necrosis factor-alpha and interleukin 1-alpha regulate transferrin receptor in human diploid fibroblasts. Relationship to the induction of ferritin heavy chain
44. Transcriptional regulation of the mouse ferritin H gene. Involvement of p300/CBP adaptor proteins in FER-1 enhancer activity
45. Activation of the ferritin H enhancer, FER-1, by the cooperative action of members of the AP1 and Spl transcription factor families
46. Ferritin content in human cancerous and noncancerous colonic tissue
47. Functional antioxidant responsive elements
48. ARE- and TRE-mediated regulation of gene expression. Response to xenobiotics and antioxidants