Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich's ataxia

FEBS Letters

Volumn 580, Issue 22, 2006, Pages 5399-5405

  Grant, LaKechia ^a   Sun, Jun ^b   Xu, Hongzhi ^a   Subramony, S H ^b   Chaires, Jonathan B ^c   Hebert, Michael D ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

Author keywords

Competition dialysis; GFP; Neurodegenerative; Trinucleotide repeat

Indexed keywords

DNA; FRATAXIN; IRON; PENTAMIDINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; DIALYSIS; DNA CONFORMATION; FRIEDREICH ATAXIA; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRON; IRON METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REPORTER GENE; TRANSCRIPTION INITIATION; TRINUCLEOTIDE REPEAT;

ANTIFUNGAL AGENTS; CELLS, CULTURED; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FRIEDREICH ATAXIA; GENES, REPORTER; HUMANS; IRON-BINDING PROTEINS; LYMPHOCYTES; NUCLEIC ACID CONFORMATION; PENTAMIDINE; TRANSCRIPTION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION;

ATAXIA;

EID: 33748796912     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.006     Document Type: Article

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