Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with β2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 23, 1997, Pages 12384-12389

  Waheed, Abdul ^a   Parkkila, Seppo ^a   Zhou, Xiao Yan ^a   Tomatsu, Shunji ^a   Tsuchihasi, Zenta ^b   Feder, John N ^b   Schatzman, Randall C ^b   Britton, Robert S ^a   Bacon, Bruce R ^a   Sly, William S ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Mcrcator Genetics Inc   (United States)

Author keywords

Degradation; Golgi processing; Intnicellular transport; Iron; Major histocompatibility complex class I protein

Indexed keywords

BETA 2 MICROGLOBULIN; CELL SURFACE PROTEIN; IRON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MUTANT PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE MUTATION; GENETIC DISORDER; GOLGI COMPLEX; HEMOCHROMATOSIS; INTRACELLULAR TRANSPORT; IRON ABSORPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN SYNTHESIS;

ANIMALS; BETA 2-MICROGLOBULIN; BIOLOGICAL TRANSPORT; COS CELLS; GENE EXPRESSION REGULATION; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; MEMBRANE PROTEINS; MUTATION;

ANIMALIA;

EID: 0030732164     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.23.12384     Document Type: Article

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