-
1
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem. 2001;276:7811-7819.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
2
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest. 2002;110:1037-1044.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
3
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306:2090-2093.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
4
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
Donovan A, Lima CA, Pinkus JL, et al. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab. 2005;1:191-200.
-
(2005)
Cell Metab
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
-
5
-
-
0037111732
-
Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
-
Weinstein DA, Roy CN, Fleming MD, et al. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood. 2002;100:3776-3781.
-
(2002)
Blood
, vol.100
, pp. 3776-3781
-
-
Weinstein, D.A.1
Roy, C.N.2
Fleming, M.D.3
-
6
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
U S A
-
Nicolas G, Bennoun M, Porteu A, et al. Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A. 2002;99:4596-4601.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennoun, M.2
Porteu, A.3
-
7
-
-
13544252463
-
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
-
Rivera S, Liu L, Nemeth E, et al. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 2005;105:1797-1802.
-
(2005)
Blood
, vol.105
, pp. 1797-1802
-
-
Rivera, S.1
Liu, L.2
Nemeth, E.3
-
8
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet. 2003;33:21-22.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
-
9
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet. 2003;361:669-673.
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
10
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet. 2004;36:77-82.
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
11
-
-
13544250486
-
Hepcidin is decreased in TFR2-hemochromatosis
-
Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. Hepcidin is decreased in TFR2-hemochromatosis. Blood. 2004;105:1803-1806.
-
(2004)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
Ganz, T.4
Camaschella, C.5
-
12
-
-
0034284595
-
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
-
Krause A, Neitz S, Magert HJ, et al. LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett. 2000;480:147-150.
-
(2000)
FEBS Lett
, vol.480
, pp. 147-150
-
-
Krause, A.1
Neitz, S.2
Magert, H.J.3
-
13
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem. 2001;276:7806-7810.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
14
-
-
0037020241
-
The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis
-
Hunter HN, Fulton DB, Ganz T, Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem. 2002;277:37597-37603.
-
(2002)
J Biol Chem
, vol.277
, pp. 37597-37603
-
-
Hunter, H.N.1
Fulton, D.B.2
Ganz, T.3
Vogel, H.J.4
-
15
-
-
1642386686
-
Organization and expression analysis of the zebrafish hepcidin gene, an antimicrobial peptide gene conserved among vertebrates
-
Shike H, Shimizu C, Lauth X, Burns JC. Organization and expression analysis of the zebrafish hepcidin gene, an antimicrobial peptide gene conserved among vertebrates. Dev Comp Immunol, 2004;28:747-754.
-
(2004)
Dev Comp Immunol
, vol.28
, pp. 747-754
-
-
Shike, H.1
Shimizu, C.2
Lauth, X.3
Burns, J.C.4
-
16
-
-
0348147599
-
Calibration and standardisation of synchrotron radiation circular dichroism and conventional circular dichroism spectrophotometers
-
Miles AJ, Wien F, Lees JG, et al. Calibration and standardisation of synchrotron radiation circular dichroism and conventional circular dichroism spectrophotometers. Spectroscopy. 2003;17:653-661.
-
(2003)
Spectroscopy
, vol.17
, pp. 653-661
-
-
Miles, A.J.1
Wien, F.2
Lees, J.G.3
-
17
-
-
0033042935
-
Estimation of the number of alpha-helical and betastrand segments in proteins using circular dichroism spectroscopy
-
Sreerama N, Venyaminov SY, Woody RW. Estimation of the number of alpha-helical and betastrand segments in proteins using circular dichroism spectroscopy. Protein Sci. 1999;8:370-380.
-
(1999)
Protein Sci
, vol.8
, pp. 370-380
-
-
Sreerama, N.1
Venyaminov, S.Y.2
Woody, R.W.3
-
18
-
-
2342510407
-
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
-
Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271-1276.
-
(2004)
J Clin Invest
, vol.113
, pp. 1271-1276
-
-
Nemeth, E.1
Rivera, S.2
Gabayan, V.3
-
19
-
-
0034691281
-
Design of salt-insensitive glycine-rich antimicrobial peptides with cyclic tricystine structures
-
Tam JP, Lu YA, Yang JL. Design of salt-insensitive glycine-rich antimicrobial peptides with cyclic tricystine structures. Biochemistry. 2000;39:7159-7169.
-
(2000)
Biochemistry
, vol.39
, pp. 7159-7169
-
-
Tam, J.P.1
Lu, Y.A.2
Yang, J.L.3
-
20
-
-
0037133343
-
Retrocyclin: A primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1
-
U S A
-
Cole AM, Hong T, Boo LM, et al. Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1. Proc Natl Acad Sci U S A. 2002;99:1813-1818.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 1813-1818
-
-
Cole, A.M.1
Hong, T.2
Boo, L.M.3
-
21
-
-
10744225120
-
Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis
-
Merryweather-Clarke AT, Cadet E, Bomford A, et al. Digenic inheritance of mutations in HAMP and HFE results in different types of haemochromatosis. Hum Mol Genet. 2003;12:2241-2247.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2241-2247
-
-
Merryweather-Clarke, A.T.1
Cadet, E.2
Bomford, A.3
-
22
-
-
1642367900
-
HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype
-
Jacolot S, Le GG, Scotet V, et al. HAMP as a modifier gene that increases the phenotypic expression of the HFE pC282Y homozygous genotype. Blood. 2004;103:2835-2840.
-
(2004)
Blood
, vol.103
, pp. 2835-2840
-
-
Jacolot, S.1
Le, G.G.2
Scotet, V.3
-
23
-
-
0344514886
-
Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload
-
Biasiotto G, Belloli S, Ruggeri G, et al. Identification of new mutations of the HFE, hepcidin, and transferrin receptor 2 genes by denaturing HPLC analysis of individuals with biochemical indications of iron overload. Clin Chem. 2003;49:1981-1988.
-
(2003)
Clin Chem
, vol.49
, pp. 1981-1988
-
-
Biasiotto, G.1
Belloli, S.2
Ruggeri, G.3
-
24
-
-
13544252463
-
Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia
-
Rivera S, Liu L, Nemeth E, et al. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 2005;105:1797-1802.
-
(2005)
Blood
, vol.105
, pp. 1797-1802
-
-
Rivera, S.1
Liu, L.2
Nemeth, E.3
-
25
-
-
14544298717
-
Hepcidin: A regulator of intestinal iron absorption and iron recycling by macrophages
-
Ganz T. Hepcidin: a regulator of intestinal iron absorption and iron recycling by macrophages. Best Pract Res Clin Haematol. 2005;18:171-182.
-
(2005)
Best Pract Res Clin Haematol
, vol.18
, pp. 171-182
-
-
Ganz, T.1
-
26
-
-
0037020241
-
The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis
-
Hunter HN, Fulton DB, Ganz T, Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem. 2002;277:37597-37603.
-
(2002)
J Biol Chem
, vol.277
, pp. 37597-37603
-
-
Hunter, H.N.1
Fulton, D.B.2
Ganz, T.3
Vogel, H.J.4
-
27
-
-
0026458378
-
Amino acid substitution matrices from protein blocks
-
U S A
-
Henikoff S, Henikoff JG. Amino acid substitution matrices from protein blocks. Proc Natl Acad Sci U S A. 1992;89:10915-10919.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 10915-10919
-
-
Henikoff, S.1
Henikoff, J.G.2
-
28
-
-
0033856445
-
Stabilization of human RNase 1 by introduction of a disulfide bond between residues 4 and 118
-
Tokyo
-
Futami J, Tada H, Seno M, Ishikami S, Yamada H. Stabilization of human RNase 1 by introduction of a disulfide bond between residues 4 and 118. J Biochem (Tokyo). 2000;128:245-250.
-
(2000)
J Biochem
, vol.128
, pp. 245-250
-
-
Futami, J.1
Tada, H.2
Seno, M.3
Ishikami, S.4
Yamada, H.5
-
29
-
-
14544305473
-
New insights into iron homeostasis through the study of non-HFE hereditary haemochromatosis
-
Roetto A, Camaschella C. New insights into iron homeostasis through the study of non-HFE hereditary haemochromatosis. Best Pract Res Clin Haematol. 2005;18:235-250.
-
(2005)
Best Pract Res Clin Haematol
, vol.18
, pp. 235-250
-
-
Roetto, A.1
Camaschella, C.2
-
30
-
-
30144431802
-
Homozygous or compound heterozygous R59G mutation of hepcidin gene in patients with adult-onset hemochromatosis
-
Biasiotto G, Daraio F, Cavallero G, et al. Homozygous or compound heterozygous R59G mutation of hepcidin gene in patients with adult-onset hemochromatosis [abstract]. Bioiron 2005 Abstracts. 2005;P139.
-
(2005)
Bioiron 2005 Abstracts
-
-
Biasiotto, G.1
Daraio, F.2
Cavallero, G.3
-
31
-
-
0027440769
-
Quality control of ER synthesized proteins: An exposed thiol group as a three-way switch mediating assembly, retention and degradation
-
Fra AM, Fagioli C, Finazzi D, Sitia R, Alberini CM. Quality control of ER synthesized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation. EMBO J. 1993;12:4755-4761.
-
(1993)
EMBO J
, vol.12
, pp. 4755-4761
-
-
Fra, A.M.1
Fagioli, C.2
Finazzi, D.3
Sitia, R.4
Alberini, C.M.5
-
32
-
-
0034726412
-
Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli
-
Schmiedl A, Breitling F, Winter CH, Queitsch I, Dubel S. Effects of unpaired cysteines on yield, solubility and activity of different recombinant antibody constructs expressed in E. coli. J Immunol Methods. 2000;242:101-114.
-
(2000)
J Immunol Methods
, vol.242
, pp. 101-114
-
-
Schmiedl, A.1
Breitling, F.2
Winter, C.H.3
Queitsch, I.4
Dubel, S.5
-
33
-
-
24744458603
-
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
-
Prepublished on June 2, as DOI 10.1182/blood-2005-04-1766
-
Rivera S, Nemeth E, Gabayan V, et al. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood. Prepublished on June 2, 2005, as DOI 10.1182/blood-2005-04-1766.
-
(2005)
Blood
-
-
Rivera, S.1
Nemeth, E.2
Gabayan, V.3
-
34
-
-
24744458603
-
-
(Now available as Blood. 2005;106:2196-2199).
-
(2005)
Blood
, vol.106
, pp. 2196-2199
-
-
-
35
-
-
27144459908
-
Competitive regulation of hepcidin mRNA by soluble and cellassociated hemojuvelin
-
Prepublished on July 5, as DOI 10.1182/blood-2005-05-1845
-
Lin L, Goldberg YP, Ganz T. Competitive regulation of hepcidin mRNA by soluble and cellassociated hemojuvelin. Blood. Prepublished on July 5, 2005, as DOI 10.1182/blood-2005-05-1845. (Now available as Blood. 2005;106;2884-2889).
-
(2005)
Blood
-
-
Lin, L.1
Goldberg, Y.P.2
Ganz, T.3
-
36
-
-
27144459908
-
-
(Now available as Blood. 2005;106;2884-2889)
-
(2005)
Blood
, vol.106
, pp. 2884-2889
-
-
|