Crystal structure of the ectodomain of human transferrin receptor

Science

Volumn 286, Issue 5440, 1999, Pages 779-782

  Lawrence, C Martin ^a,b   Ray, Sanjoy ^a,c   Babyonyshev, Marina ^a   Galluser, Renate ^a   Borhani, David W ^a,d   Harrison, Stephen C ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPEPTIDASE; APOTRANSFERRIN; CARBOXYPEPTIDASE; CLATHRIN; GAMMA GLUTAMYL HYDROLASE; IRON; TRANSFERRIN; TRANSFERRIN RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CELL SURFACE; CRYSTAL STRUCTURE; ENDOCYTOSIS; ENDOSOME; HUMAN; MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CARBOXYPEPTIDASES; CELL MEMBRANE; CHO CELLS; CONSERVED SEQUENCE; CRICETINAE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; FERRIC COMPOUNDS; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, TRANSFERRIN; TRANSFERRIN;

EID: 0033595794     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.286.5440.779     Document Type: Article

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46. We thank D. Thiel and other staff members at CHESS for assistance with data collection at the F-1 beamline; W. Minor for help in data processing; R. Davis for help with CHO cell expression; P. Aisen, N. Andrews, M. Eck, and M. Wessling-Resnick for discussion; and P. Bjorkman, M. Bennet, and C. Enns for communicating results before publication. C.M.L is an Armenise Fellow of the Harvard Medical School Center for Structural Biology.