The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis

Human Molecular Genetics

Volumn 8, Issue 3, 1999, Pages 425-430

  Wong, Alice ^a   Yang, Joy ^a   Cavadini, Patrizia ^b   Gellera, Cinzia ^b   Lonnerdal, Bo ^a   Taroni, Franco ^b   Cortopassi, Gino ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DEPARTMENT OF NEUROSURGERY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CASPASE 3; CHELATING AGENT; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FRATAXIN; HYDROGEN PEROXIDE; IRON; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST CULTURE; FRIEDREICH ATAXIA; GENE MUTATION; HUMAN; HUMAN CELL; INTRON; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PRIORITY JOURNAL;

ATAXIA;

EID: 0033054177     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/8.3.425     Document Type: Article

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