-
1
-
-
0033597780
-
Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
-
Kawabata H, Yang R, Hirama T, et al. Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family. J Biol Chem 1999;274:20826-32.
-
(1999)
J Biol Chem
, vol.274
, pp. 20826-20832
-
-
Kawabata, H.1
Yang, R.2
Hirama, T.3
-
2
-
-
0034007995
-
Transferrin receptor 2: Continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis
-
Fleming RE, Migas MC, Holden CC, et al. Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis. Proc Natl Acad Sci U S A 2000;97:2214-19.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2214-2219
-
-
Fleming, R.E.1
Migas, M.C.2
Holden, C.C.3
-
3
-
-
0034595856
-
Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo
-
Kawabata H, Germain RS, Vuong PT, et al. Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo. J Biol Chem 2000;275:16618-25.
-
(2000)
J Biol Chem
, vol.275
, pp. 16618-16625
-
-
Kawabata, H.1
Germain, R.S.2
Vuong, P.T.3
-
4
-
-
0034623930
-
Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE
-
West AP Jr, Bennett MJ, Sellers VM, et al. Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. J Biol Chem 2000;275:38135-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 38135-38138
-
-
West Jr., A.P.1
Bennett, M.J.2
Sellers, V.M.3
-
5
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
Camaschella C, Roetto A, Cali A, et al. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat Genet 2000;25:14-15.
-
(2000)
Nat Genet
, vol.25
, pp. 14-15
-
-
Camaschella, C.1
Roetto, A.2
Cali, A.3
-
6
-
-
0141607526
-
Hemochromatosis due to mutations in transferrin receptor 2
-
Roetto A, Daraio F, Alberti F, et al. Hemochromatosis due to mutations in transferrin receptor 2. Blood Cells Mol Dis 2002;29:465-70.
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 465-470
-
-
Roetto, A.1
Daraio, F.2
Alberti, F.3
-
7
-
-
0036678091
-
Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis
-
Fleming RE, Ahmann JR, Migas MC, et al. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis. Proc Natl Acad Sci U S A 2002;99:10653-8.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10653-10658
-
-
Fleming, R.E.1
Ahmann, J.R.2
Migas, M.C.3
-
8
-
-
0034284595
-
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
-
Krause A, Neitz S, Magert HJ, et al. LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity. FEBS Lett 2000;480:147-50.
-
(2000)
FEBS Lett
, vol.480
, pp. 147-150
-
-
Krause, A.1
Neitz, S.2
Magert, H.J.3
-
9
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, et al. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001;276:7806-10.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
-
10
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, et al. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001;276:7811-19.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
11
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002;110:1037-44.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
12
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I, et al. Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A 2001;98:8780-5.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
13
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, et al. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 2003;33:21-2.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
-
14
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 2003;361:669-73.
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
15
-
-
0038312385
-
Decreased liver hepcidin expression in the Hfe knockout mouse
-
Ahmad KA, Ahmann JR, Migas MC, et al. Decreased liver hepcidin expression in the Hfe knockout mouse. Blood Cell Mol Dis 2002;29:361-6.
-
(2002)
Blood Cell Mol Dis
, vol.29
, pp. 361-366
-
-
Ahmad, K.A.1
Ahmann, J.R.2
Migas, M.C.3
-
16
-
-
2442426523
-
An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice
-
Roy CN, Custodio AO, de Graaf J, et al. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nat Genet 2004;36:481-5.
-
(2004)
Nat Genet
, vol.36
, pp. 481-485
-
-
Roy, C.N.1
Custodio, A.O.2
De Graaf, J.3
-
17
-
-
3442875926
-
Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE
-
Frazer DM, Wilkins SJ, Millard KN, et al. Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE. Br J Haematol 2004;126:434-6.
-
(2004)
Br J Haematol
, vol.126
, pp. 434-436
-
-
Frazer, D.M.1
Wilkins, S.J.2
Millard, K.N.3
-
18
-
-
3042636759
-
The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepotocytes
-
Lee P, Peng H, Gelbart T, et al. The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepotocytes. Proc Natl Acad Sci U S A 2004;101:9203-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9203-9205
-
-
Lee, P.1
Peng, H.2
Gelbart, T.3
-
19
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 2004;36:77-82.
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
20
-
-
0033168767
-
The C282Y mutation causing hereditary hemochromatosis does not produce a null allele
-
Levy JE, Montross LK, Cohen DE, et al. The C282Y mutation causing hereditary hemochromatosis does not produce a null allele. Blood 1999;94:9-11.
-
(1999)
Blood
, vol.94
, pp. 9-11
-
-
Levy, J.E.1
Montross, L.K.2
Cohen, D.E.3
-
21
-
-
2942608896
-
Inactivation of the murine transferrin receptor 2 gene using the Cre recombinase:loxP system
-
Wallace DF, Tonks ID, Zournazi A, et al. Inactivation of the murine transferrin receptor 2 gene using the Cre recombinase:loxP system. Genesis 2004;39:38-41.
-
(2004)
Genesis
, vol.39
, pp. 38-41
-
-
Wallace, D.F.1
Tonks, I.D.2
Zournazi, A.3
-
22
-
-
21044450599
-
Prohepcidin localises to the Golgi compartment and secretory pathway in hepatocytes
-
in press
-
Wallace DF, Summerville L, Lusby PE, et al. Prohepcidin localises to the Golgi compartment and secretory pathway in hepatocytes. J Hepatol 2005 (in press).
-
(2005)
J Hepatol
-
-
Wallace, D.F.1
Summerville, L.2
Lusby, P.E.3
-
23
-
-
0014267781
-
A simple technique for measuring storage iron concentrations in formalinised liver samples
-
Torrance JD, Bothwell TH. A simple technique for measuring storage iron concentrations in formalinised liver samples. S Afr J Med Sci 1968;33:9-11.
-
(1968)
S Afr J Med Sci
, vol.33
, pp. 9-11
-
-
Torrance, J.D.1
Bothwell, T.H.2
-
24
-
-
0036838570
-
Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice
-
Dupic F, Fruchon S, Bensaid M, et al. Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice. Gut 2002;51:648-53.
-
(2002)
Gut
, vol.51
, pp. 648-653
-
-
Dupic, F.1
Fruchon, S.2
Bensaid, M.3
-
25
-
-
1442306702
-
Non-HFE hemochromatosis
-
Pietrangelo A. Non-HFE hemochromatosis. Hepatology 2004;39:21-9.
-
(2004)
Hepatology
, vol.39
, pp. 21-29
-
-
Pietrangelo, A.1
-
26
-
-
10744226568
-
Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice
-
Courselaud B, Troadec MB, Fruchon S, et al. Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice. Blood Cells Mol Dis 2004;32:283-9.
-
(2004)
Blood Cells Mol Dis
, vol.32
, pp. 283-289
-
-
Courselaud, B.1
Troadec, M.B.2
Fruchon, S.3
-
27
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E, Roetto A, Garozzo G, et al. Hepcidin is decreased in TFR2 hemochromatosis. Blood 2005;105:1803-6.
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
-
28
-
-
19944427107
-
Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis
-
Kawabata H, Fleming RE, Gui D, et al. Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis. Blood 2005;105:376-81.
-
(2005)
Blood
, vol.105
, pp. 376-381
-
-
Kawabata, H.1
Fleming, R.E.2
Gui, D.3
-
29
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004;306:2090-3.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
30
-
-
1642315903
-
Functional differences between hepcidin 1 and 2 in transgenic mice
-
Lou DQ, Nicolas G, Lesbordes JC, et al. Functional differences between hepcidin 1 and 2 in transgenic mice. Blood 2004;103:2816-21.
-
(2004)
Blood
, vol.103
, pp. 2816-2821
-
-
Lou, D.Q.1
Nicolas, G.2
Lesbordes, J.C.3
|