메뉴 건너뛰기




Volumn 294, Issue 1, 1999, Pages 239-245

The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor

Author keywords

Class I MHC homolog; HFE; Inhibition; Iron overload; Surface plasmon resonance

Indexed keywords

CELL SURFACE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TRANSFERRIN; TRANSFERRIN RECEPTOR;

EID: 0033585129     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3252     Document Type: Article
Times cited : (169)

References (22)
  • 3
    • 85030363026 scopus 로고    scopus 로고
    • Crystall structure of the hereditory hemochromatosis protein HFE complexed with transferrin receptor
    • Bennett M. J., Lebrón J. A., Bjorkman P. J. Crystall structure of the hereditory hemochromatosis protein HFE complexed with transferrin receptor. Nature. in the press:1999.
    • (1999) Nature
    • Bennett, M.J.1    Lebrón, J.A.2    Bjorkman, P.J.3
  • 4
    • 0025878342 scopus 로고
    • Crystallization and X-ray diffraction studies of a soluble form of the human transferrin receptor
    • Borhani D. W., Harrison S. C. Crystallization and X-ray diffraction studies of a soluble form of the human transferrin receptor. J. Mol. Biol. 218:1991;685-689.
    • (1991) J. Mol. Biol. , vol.218 , pp. 685-689
    • Borhani, D.W.1    Harrison, S.C.2
  • 6
    • 0019773013 scopus 로고
    • Physical characterization of the transferrin receptor in human placentae
    • Enns C. A., Sussman H. H. Physical characterization of the transferrin receptor in human placentae. J. Biol. Chem. 256:1981;9820-9823.
    • (1981) J. Biol. Chem. , vol.256 , pp. 9820-9823
    • Enns, C.A.1    Sussman, H.H.2
  • 10
    • 0032555601 scopus 로고    scopus 로고
    • Co-trafficking of HFE, a non-classical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation
    • Gross C. N., Irrinki A., Feder J. N., Enns C. A. Co-trafficking of HFE, a non-classical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation. J. Biol. Chem. 273:1998;22068-22074.
    • (1998) J. Biol. Chem. , vol.273 , pp. 22068-22074
    • Gross, C.N.1    Irrinki, A.2    Feder, J.N.3    Enns, C.A.4
  • 12
    • 0033020518 scopus 로고    scopus 로고
    • The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis
    • Lebrón J. A., Bjorkman P. J. The transferrin receptor binding site on HFE, the class I MHC-related protein mutated in hereditary hemochromatosis. J. Mol. Biol. 289:1999;1109-1118.
    • (1999) J. Mol. Biol. , vol.289 , pp. 1109-1118
    • Lebrón, J.A.1    Bjorkman, P.J.2
  • 13
    • 0032478524 scopus 로고    scopus 로고
    • Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
    • Lebrón J. A., Bennett M. J., Vaughn D. E., Chirino A. J., Snow P. M., Mintier G. A., Feder J. N., Bjorkman P. J. Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor. Cell. 93:1998;111-123.
    • (1998) Cell , vol.93 , pp. 111-123
    • Lebrón, J.A.1    Bennett, M.J.2    Vaughn, D.E.3    Chirino, A.J.4    Snow, P.M.5    Mintier, G.A.6    Feder, J.N.7    Bjorkman, P.J.8
  • 14
    • 0027916175 scopus 로고
    • Biospecific interaction analysis using biosensor technology
    • Malmqvist M. Biospecific interaction analysis using biosensor technology. Nature. 361:1993;186-187.
    • (1993) Nature , vol.361 , pp. 186-187
    • Malmqvist, M.1
  • 17
    • 0031567095 scopus 로고    scopus 로고
    • The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells
    • Richardson D. R., Ponka P. The molecular mechanisms of the metabolism and transport of iron in normal and neoplastic cells. Biochim. Biophys. Acta. 1331:1997;1-40.
    • (1997) Biochim. Biophys. Acta , vol.1331 , pp. 1-40
    • Richardson, D.R.1    Ponka, P.2
  • 18
    • 0033605595 scopus 로고    scopus 로고
    • The hereditary hemochromatosis protein, HFE, specifically regulates Tf-mediated iron uptake in HeLa cells
    • Roy C. N., Penny D. M., Feder J. N., Enns C. A. The hereditary hemochromatosis protein, HFE, specifically regulates Tf-mediated iron uptake in HeLa cells. J. Biol. Chem. 274:1999;9022-9028.
    • (1999) J. Biol. Chem. , vol.274 , pp. 9022-9028
    • Roy, C.N.1    Penny, D.M.2    Feder, J.N.3    Enns, C.A.4
  • 19
    • 0033545852 scopus 로고    scopus 로고
    • Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: Implications for cellular homeostasis
    • Salter-Cid L., Brunmark A., Li Y., Leturco D., Peterson P. A., Jackson M. R., Yang Y. Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: implications for cellular homeostasis. Proc. Natl Acad. Sci. USA. 96:1999;5434-5439.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 5434-5439
    • Salter-Cid, L.1    Brunmark, A.2    Li, Y.3    Leturco, D.4    Peterson, P.A.5    Jackson, M.R.6    Yang, Y.7
  • 20
    • 0024383535 scopus 로고
    • Antigen recognition by class I-restricted T lymphocytes
    • Townsend A., Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Annu. Rev. Immunol. 7:1989;601-624.
    • (1989) Annu. Rev. Immunol. , vol.7 , pp. 601-624
    • Townsend, A.1    Bodmer, H.2
  • 21
    • 0030732164 scopus 로고    scopus 로고
    • Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with β2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells
    • Waheed A., Parkkila S., Zhou X. Y., Tomatsu S., Tsuchihashi Z., Feder J. N., Schatzman R. C., Britton R. S., Bacon B. R., Sly W. S. Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with β2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells. Proc. Natl Acad. Sci. USA. 94:1997;12384-12389.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 12384-12389
    • Waheed, A.1    Parkkila, S.2    Zhou, X.Y.3    Tomatsu, S.4    Tsuchihashi, Z.5    Feder, J.N.6    Schatzman, R.C.7    Britton, R.S.8    Bacon, B.R.9    Sly, W.S.10
  • 22
    • 0021265943 scopus 로고
    • The effect of the iron saturation of transferrin on its binding and uptake by rabbit reticulocytes
    • Young S. P., Bomford A., Williams R. The effect of the iron saturation of transferrin on its binding and uptake by rabbit reticulocytes. Biochem. J. 219:1984;505-510.
    • (1984) Biochem. J. , vol.219 , pp. 505-510
    • Young, S.P.1    Bomford, A.2    Williams, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.