Role of the mitochondrial Hsp70s, Ssc1 and Ssq1, in the maturation of Yfh1

Molecular and Cellular Biology

Volumn 20, Issue 10, 2000, Pages 3677-3684

  Voisine, Cindy ^a   Schilke, Brenda ^a   Ohlson, Maikke ^a   Beinert, Helmut ^b   Marszalek, Jaroslaw ^a,c   Craig, Elizabeth A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN   (United States)

^c UNIVERSITY OF GDA SK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 70;

ARTICLE; GENE OVEREXPRESSION; MEMBRANE DAMAGE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE;

ACONITATE HYDRATASE; BIOLOGICAL TRANSPORT; CALCIUM-TRANSPORTING ATPASES; CELL COMPARTMENTATION; ELECTRON TRANSPORT COMPLEX III; FUNGAL PROTEINS; HSP70 HEAT-SHOCK PROTEINS; IRON; IRON-BINDING PROTEINS; IRON-SULFUR PROTEINS; MITOCHONDRIA; MOLECULAR CHAPERONES; OXYGEN CONSUMPTION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUCCINATE DEHYDROGENASE;

EID: 0034053969     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.10.3677-3684.2000     Document Type: Article

References (48)

1. Babcock, M., D. de Silva, R. Oaks, S. Davis-Kaplan, S. Jiralerspong, L. Montermini, M. Pandolfo, and J. Kaplan. 1997. Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science 276: 1709-1712.
2. Beinert, H. 1978. Micro methods for the quantitative determination of iron and copper in biological material. Methods Enzymol. 54:435-445.
3. Blond-Elguindi, S., S. Cwirla, W. Dower, R. Lipshutz, S. Sprang, J. Sambrook, and M. J. Gething. 1993. Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP. Cell 75: 717-728.
4. Branda, S., P. Cavadini, J. Adamec, F. Kalousek, F. Taroni, and G. Isaya. 1999. Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase. J. Biol. Chem. 274:22763-22769.
5. Branda, S., Z. Yang, A. Chew, and G. Isaya. 1999. Mitochondrial intermediate peptidase and the yeast frataxin homolog together maintain mitochondrial homeostasis in Saccharomyces cerevisiae. Hum. Mol. Genet. 8:1099-1110.
6. Bukau, B., and A. L. Horwich. 1998. The Hsp70 and Hsp60 chaperone machines. Cell 92:351-366.
7. Campuzano, V., L. Montermini, M. D. Molto, L. Pianese, M. Cessee, F. Cavalcanti, and E. Monros. 1996. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 271: 1423-1427.
8. Chazotte, B., and C. R. Hackenbrock. 1989. Lateral diffusion as a rate-limiting step in ubiquinone-mediated mitochondrial electron transport. J. Biol. Chem. 264:4978-4985.
9. Dean, D. R., J. T. Bolin, and L. Zheng. 1993. Nitrogenase metalloclusters: structures, organization, and synthesis. J. Bacteriol. 175:6737-6744.
10. Fansler, B., and J. M. Lowenstein. 1969. Aconitase from pig heart. Methods Enzymol. 13:26-30.
11. Flynn, G., J. Pohl, M. Flocco, and J. Rothman. 1991. Peptide-binding specificity of the molecular chaperone BiP. Nature 353:725-730.
12. Foury, F., and O. Cazzalini. 1997. Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria. FEBS Lett. 411:373-377.
13. Fridovitch, I. 1995. Superoxide radical and superoxide dismutases. Annu. Rev. Biochem. 64:97-112.
14. Fu, W., R. F. Jack, T. V. Morgan, D. R. Dean, and M. K. Johnson. 1994. nifU gene product from Azotobacter vinelandii is a homodimer that contains two identical [2Fe-2S] clusters. Biochemistry 33:13455-13463.
15. Gambill, B. D., W. Voos, P. J. Kang, B. Miao, T. Langer, E. A. Craig, and N. Pfanner. 1993. A dual role for mitochondrial heat shock protein 70 in membrane translocation of preproteins. J. Cell Biol. 123:109-117.
16. Goldstein, S., D. Meyerstein, and G. Czapski. 1993. The Fenton reagents. Free Radic. Biol. Med. 15:435-445.
17. Graham, L. A., and B. L. Trumpower. 1991. Mutational analysis of the mitochondrial Rieske iron-sulfur protein of Saccharomyces cerevisiae. J. Biol. Chem. 266:22485-22492.
18. Hakes, D. J., and J. E. Dixon. 1992. New vectors for high level expression of recombinant proteins in bacteria. Anal. Biochem. 202:293-298.
19. Hartl, F. U. 1996. Molecular chaperones in cellular protein folding. Nature 381:571-580.
20. James, P., C. Pfund, and E. Craig. 1997. Functional specificity among Hsp70 molecular chaperones. Science 275:387-389.
21. Johnson, J. L., and E. A. Craig. 1997. Protein folding in vivo: unraveling complex pathways. Cell 90:201-204.
22. Jones, E. W. 1991. Tackling the protease problem in Saccharomyces cerevisiae. Methods Enzymol. 194:428-453.
23. Kang, P. J., J. Ostermann, J. Shilling, W. Neupert, E. A. Craig, and N. Pfanner. 1990. Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins. Nature 348:137-143.
24. Kennedy, M. C., T. A. Kent, M. Emptage, H. Merkle, H. Beinert, and E. Münck. 1984. Evidence for the formation of a linear [3Fe-4S] cluster in partially unfolded aconitase. J. Biol. Chem. 259:14463-14471.
25. Kispal, G., P. Csere, C. Prohl, and R. Lill. 1999. The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins. EMBO J. 18:3981-3989.
26. Knight, S. A. B., N. B. V. Sepuri, D. Pain, and A. Dancis. 1998. Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis. J. Biol. Chem. 273:18389-18393.
27. Lamarche, J. B., M. Cote, and B. Lemieux. 1980. The cardiomyopathy of Friedreich's ataxia morphological observations in 3 cases. Can. J. Neuro. Sci. 7:389-396.
28. Mathai, J. C., Z. E. Sauna, O. John, and V. Sitaramam. 1993. Rate-limiting step in electron transport. J. Biol. Chem. 268:15442-15454.
29. Miao, B., J. E. Davis, and E. A. Craig. 1997. Mge1 functions as a nucleotide release factor for Ssc1, a mitochondrial Hsp70 of Saccharomyces cerevisiae. J. Mol. Biol. 265:541-552.
30. Neupert, W. 1997. Protein import into mitochondria. Annu. Rev. Biochem. 66:863-917.
31. Pfanner, N., E. A. Craig, and A. Honlinger. 1997. Mitochondrial preprotein translocase. Annu. Rev. Cell Dev. Biol. 13:25-51.
32. Radisky, D. C., M. C. Babcock, and J. Kaplan. 1999. The yeast frataxin homologue mediates mitochondrial iron efflux. J. Biol. Chem. 274:4497-4499.
33. Rassow, J., A. Maarse, E. Krainer, M. Kubrich, H. Muller, M. Meijer, E. Craig, and N. Pfanner. 1994. Mitochondrial protein import: biochemical and genetic evidence for interaction of matrix Hsp70 and the inner membrane protein Mim44. J. Cell Biol. 127:1547-1556.
34. Rothstein, R. 1991. Targeting, disruption, replacement and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194:281-301.
35. Rötig, A., P. de Lonlay, D. Chretien, F. Foury, M. Koenig, D. Sidi, A. Munnich, and P. Rustin. 1997. Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia. Nat. Genet. 17:215-217.
36. Rudiger, S., L. Germeroth, J. Schneider-Mergener, and B. Bukau. 1997. Substrate specificity of the DnaK chaperone determined by screening cellulose-bound peptide libraries. EMBO J. 16:1501-1507.
37. Ryan, K. R., and R. E. Jensen. 1995. Protein translocation across mitochondrial membranes: what a long, strange trip it is. Cell 83:517-519.
38. Sakuragi, S., Q. Liu, and E. Craig. 1999. Interaction between the nucleotide exchange factor Mge1 and the mitochondrial Hsp70 Ssc1. J. Biol. Chem. 274:11275-11282.
39. Schatz, G., and B. Dobberstein. 1996. Common principles of protein translocation across membranes. Science 271:1519-1526.
40. Schilke, B., J. Forster, J. Davis, P. James, W. Walter, S. Laloraya, J. Johnson, B. Miao, and E. Craig. 1996. Cold-sensitivity of an S. cerevisiae mutant lacking a newly identified mitochondrial Hsp70 is suppressed by loss of mitochondrial DNA. J. Cell Biol. 134:603-614.
41. Schilke, B., C. Voisine, H. Beinert, and E. Craig. 1999. Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 96:10206-10211.
42. Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
43. Strain, J., C. R. Lorenz, J. Bode, S. Garland, G. A. Smolen, D. T. Ta, L. E. Vickery, and V. C. Culotta. 1998. Suppressors of superoxide dismutase (SOD1) deficiency in Saccharomyces cerevisiae. J. Biol. Chem. 273:31138-31144.
44. Tangerås, A., T. Flatmark, D. Bäckström, and A. Ehrenberg. 1980. Mitochondrial iron not bound in heme and iron-sulfur centers. Biochim. Biophys. Acta 589:162-175.
45. Voos, W., B. D. Gambill, B. Guiard, N. Pfanner, and E. A. Craig. 1993. Presequence and mature parts of preproteins strongly influence the dependence of mitochondrial protein import on heat shock protein 70 in the matrix. J. Cell Biol. 123:119-123.
46. Watson, K., E. Bertoli, and D. E. Griffiths. 1975. Phase transitions in yeast mitochondrial membranes. Biochem. J. 146:401-407.
47. Zheng, L., V. L. Cash, D. H. Flint, and D. R. Dean. 1998. Assembly of iron-sulfur clusters. J. Biol. Chem. 273:13264-13272.
48. Zheng, L., R. H. White, V. L. Cash, R. F. Jack, and D. R. Dean. 1993. Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis. Proc. Natl. Acad. Sci. USA 90:2754-2758.