Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

Neuron

Volumn 93, Issue 5, 2017, Pages 1015-1034

  Menzies, Fiona M ^a   Fleming, Angeleen ^a   Caricasole, Andrea ^b   Bento, Carla F ^a   Andrews, Stephen P ^b   Ashkenazi, Avraham ^a   Füllgrabe, Jens ^a   Jackson, Anne ^a   Jimenez Sanchez, Maria ^a   Karabiyik, Cansu ^a   Licitra, Floriana ^a   Lopez Ramirez, Ana ^a   Pavel, Mariana ^a   Puri, Claudia ^a   Renna, Maurizio ^a   Ricketts, Thomas ^a   Schlotawa, Lars ^a   Vicinanza, Mariella ^a   Won, Hyeran ^a   Zhu, Ye ^a   Skidmore, John ^b   Rubinsztein, David C ^a   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Alzheimer's disease; autophagy; dementia; Huntington's disease; lysosome; motor neuron disease; neurodegeneration; Parkinson's disease; tau

Indexed keywords

EVEROLIMUS; POLYGLUTAMINE; RAPAMYCIN; RAPAMYCIN DERIVATIVE; PROTEIN;

ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; AUTOPHAGY; BIOACCUMULATION; CELL FUNCTION; CORE AUTOPHAGY GENE; CYTOLOGY; CYTOPLASM; DEGENERATIVE DISEASE; FRONTOTEMPORAL DEMENTIA; GENE; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; HUNTINGTON CHOREA; KNOCKOUT MOUSE; LYSOSOMAL DISEASE; LYSOSOME; NERVE CELL DIFFERENTIATION; NERVE DEGENERATION; NERVOUS SYSTEM FUNCTION; NEURAL STEM CELL; NONHUMAN; PARKINSON DISEASE; PATHOPHYSIOLOGY; PROTEIN AGGREGATION; PROTEIN DEFECT; PROTEIN LOCALIZATION; REVIEW; TAUOPATHY; TRANSCRIPTION REGULATION; TUBEROUS SCLEROSIS; UPREGULATION; ANIMAL; METABOLISM; MOTONEURON; NEURODEGENERATIVE DISEASES; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AUTOPHAGY; HUMANS; LYSOSOMES; MOTOR NEURONS; NEURODEGENERATIVE DISEASES; PROTEINS; SIGNAL TRANSDUCTION;

EID: 85014799386     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2017.01.022     Document Type: Review

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