-
1
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signalling regulation
-
Yang, Z. & Klionsky, D. J. Mammalian autophagy: Core molecular machinery and signalling regulation. Curr. Opin. Cell Biol. 22, 124-131 (2010).
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
2
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima, N., Levine, B., Cuervo, A. M. & Klionsky, D. J. Autophagy fights disease through cellular self-digestion. Nature 451, 1069-1075 (2008).
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
3
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine, B., Mizushima, N. & Virgin, H. W. Autophagy in immunity and inflammation. Nature 469, 323-335 (2011).
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
4
-
-
80054025654
-
The role of Atg proteins in autophagosome formation
-
Mizushima, N., Yoshimori, T. & Ohsumi, Y. The role of Atg proteins in autophagosome formation. Annu. Rev. Cell Dev. Biol. 27, 107-132 (2011).
-
(2011)
Annu. Rev. Cell Dev. Biol.
, vol.27
, pp. 107-132
-
-
Mizushima, N.1
Yoshimori, T.2
Ohsumi, Y.3
-
5
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
Axe, E. L. et al. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J. Cell Biol. 182, 685-701 (2008).
-
(2008)
J. Cell Biol.
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
-
6
-
-
67349269904
-
Autophagy enhances the presentation of endogenous viral antigens on MHC class i molecules during HSV-1 infection
-
English, L. et al. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat. Immunol. 10, 480-487 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 480-487
-
-
English, L.1
-
7
-
-
77952495224
-
Mitochondria supply membranes for autophagosome biogenesis during starvation
-
Hailey, D. W. et al. Mitochondria supply membranes for autophagosome biogenesis during starvation. Cell 141, 656-667 (2010).
-
(2010)
Cell
, vol.141
, pp. 656-667
-
-
Hailey, D.W.1
-
8
-
-
77955131007
-
Plasma membrane contributes to the formation of pre-autophagosomal structures
-
Ravikumar, B., Moreau, K., Jahreiss, L., Puri, C. & Rubinsztein, D. Plasma membrane contributes to the formation of pre-autophagosomal structures. Nat. Cell Biol. 12, 747-757 (2010).
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 747-757
-
-
Ravikumar, B.1
Moreau, K.2
Jahreiss, L.3
Puri, C.4
Rubinsztein, D.5
-
9
-
-
77954197767
-
Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae
-
Van der Vaart, A., Griffith, J. & Reggiori, F. Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae. Mol. Biol. Cell. 21, 2270-2284 (2010).
-
(2010)
Mol. Biol. Cell.
, vol.21
, pp. 2270-2284
-
-
Van Der Vaart, A.1
Griffith, J.2
Reggiori, F.3
-
10
-
-
84880844303
-
Membrane remodeling bythe PX-BAR protein SNX18 promotes autophagosome formation
-
Knaevelsrud, H. et al. Membrane remodeling bythe PX-BAR protein SNX18 promotes autophagosome formation. J. Cell Biol. 202, 331-349 (2013).
-
(2013)
J. Cell Biol.
, vol.202
, pp. 331-349
-
-
Knaevelsrud, H.1
-
11
-
-
84884220705
-
Diverse autophagosome membrane sources coalesce in recycling endosomes
-
Puri, C., Renna, M., Bento, C. F., Moreau, K. & Rubinsztein, D. C. Diverse autophagosome membrane sources coalesce in recycling endosomes. Cell 154, 1285-1299 (2013).
-
(2013)
Cell
, vol.154
, pp. 1285-1299
-
-
Puri, C.1
Renna, M.2
Bento, C.F.3
Moreau, K.4
Rubinsztein, D.C.5
-
12
-
-
84872586081
-
Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy
-
Kim, J. et al. Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell 152, 290-303 (2013).
-
(2013)
Cell
, vol.152
, pp. 290-303
-
-
Kim, J.1
-
13
-
-
84865028332
-
Autophagy regulation through Atg9 traffic
-
Reggiori, F. & Tooze, S. A. Autophagy regulation through Atg9 traffic. J. Cell Biol. 198, 151-153 (2012).
-
(2012)
J. Cell Biol.
, vol.198
, pp. 151-153
-
-
Reggiori, F.1
Tooze, S.A.2
-
14
-
-
77951221542
-
The role of the Atg1/ULK1 complex in autophagy regulation
-
Mizushima, N. The role of the Atg1/ULK1 complex in autophagy regulation. Curr. Opin. Cell Biol. 22, 132-139 (2010).
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 132-139
-
-
Mizushima, N.1
-
15
-
-
77950465542
-
Current knowledge of the pre-autophagosomal structure (PAS)
-
Suzuki, K. & Ohsumi, Y. Current knowledge of the pre-autophagosomal structure (PAS). FEBS Lett. 584, 1280-1286 (2010).
-
(2010)
FEBS Lett.
, vol.584
, pp. 1280-1286
-
-
Suzuki, K.1
Ohsumi, Y.2
-
16
-
-
37549043217
-
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
-
Sanjuan, M. A. et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 450, 1253-1257 (2007).
-
(2007)
Nature
, vol.450
, pp. 1253-1257
-
-
Sanjuan, M.A.1
-
17
-
-
32544432831
-
Presynaptic terminals independently regulate synaptic clustering and autophagy of GABAA receptors in Caenorhabditis elegans
-
Rowland, A. M., Richmond, J. E., Olsen, J. G., Hall, D. H. & Bamber, B. A. Presynaptic terminals independently regulate synaptic clustering and autophagy of GABAA receptors in Caenorhabditis elegans. J. Neurosci. 26, 1711-1720 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 1711-1720
-
-
Rowland, A.M.1
Richmond, J.E.2
Olsen, J.G.3
Hall, D.H.4
Bamber, B.A.5
-
18
-
-
84861663288
-
Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner
-
Bejarano, E. et al. Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner. Mol. Biol. Cell 23, 2156-2169 (2012).
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2156-2169
-
-
Bejarano, E.1
-
19
-
-
79952792541
-
Autophagy: A pathway that contributes to connexin degradation
-
Lichtenstein, A., Minogue, P. J., Beyer, E. C. & Berthoud, V. M. Autophagy: A pathway that contributes to connexin degradation. J. Cell Sci. 124, 910-920 (2011).
-
(2011)
J. Cell Sci.
, vol.124
, pp. 910-920
-
-
Lichtenstein, A.1
Minogue, P.J.2
Beyer, E.C.3
Berthoud, V.M.4
-
20
-
-
77950993997
-
Ultrastructure and regulation of lateralized connexin43 in the failing heart
-
Hesketh, G. G. et al. Ultrastructure and regulation of lateralized connexin43 in the failing heart. Circ. Res. 106, 1153-1163 (2010).
-
(2010)
Circ. Res.
, vol.106
, pp. 1153-1163
-
-
Hesketh, G.G.1
-
21
-
-
84862624689
-
Internalized gap junctions are degraded by autophagy
-
Fong, J. T. et al. Internalized gap junctions are degraded by autophagy. Autophagy 8, 794-811 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 794-811
-
-
Fong, J.T.1
-
22
-
-
70449519976
-
Eps15 interacts with ubiquitinated Cx43 and mediates its internalization
-
Girao, H., Catarino, S. & Pereira, P. Eps15 interacts with ubiquitinated Cx43 and mediates its internalization. Exp. Cell Res. 315, 3587-3597 (2009).
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 3587-3597
-
-
Girao, H.1
Catarino, S.2
Pereira, P.3
-
23
-
-
78349283001
-
Characterization of hTERT-immortalized osteoblast cell lines generated from wild-type and connexin43-null mouse calvaria
-
Thi, M. M., Urban-Maldonado, M., Spray, D. C. & Suadicani, S. O. Characterization of hTERT-immortalized osteoblast cell lines generated from wild-type and connexin43-null mouse calvaria. Am. J. Physiol. Cell Physiol. 299, C994-C1006 (2010).
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.299
-
-
Thi, M.M.1
Urban-Maldonado, M.2
Spray, D.C.3
Suadicani, S.O.4
-
24
-
-
77953122645
-
LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis
-
Weidberg, H. et al. LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J. 29, 1792-1802 (2010).
-
(2010)
EMBO J.
, vol.29
, pp. 1792-1802
-
-
Weidberg, H.1
-
25
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8, 445-544 (2012).
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
-
26
-
-
34548077575
-
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
-
Kimura, S., Noda, T. & Yoshimori, T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3, 452-460 (2007).
-
(2007)
Autophagy
, vol.3
, pp. 452-460
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
27
-
-
0034757336
-
Bimodal inhibition of connexin 43 gap junctions decreases ACTH-induced steroidogenesis and increases bovine adrenal cell population growth
-
Shah, U. S. & Murray, S. A. Bimodal inhibition of connexin 43 gap junctions decreases ACTH-induced steroidogenesis and increases bovine adrenal cell population growth. J. Endocrinol. 171, 199-208 (2001).
-
(2001)
J. Endocrinol.
, vol.171
, pp. 199-208
-
-
Shah, U.S.1
Murray, S.A.2
-
28
-
-
0030042852
-
Evidence that disruption of connexon particle arrangements in gap junction plaques is associated with inhibition of gap junctional communication by a glycyrrhetinic acid derivative
-
Goldberg, G. S. et al. Evidence that disruption of connexon particle arrangements in gap junction plaques is associated with inhibition of gap junctional communication by a glycyrrhetinic acid derivative. Exp. Cell Res. 222, 48-53 (1996).
-
(1996)
Exp. Cell Res.
, vol.222
, pp. 48-53
-
-
Goldberg, G.S.1
-
29
-
-
69949090953
-
Connexins: A myriad of functions extending beyond assembly of gap junction channels
-
Dbouk, H. A., Mroue, R. M., El-Sabban, M. E. & Talhouk, R. S. Connexins: A myriad of functions extending beyond assembly of gap junction channels. Cell Commun. Signaling 7, 4 (2009).
-
(2009)
Cell Commun. Signaling
, vol.7
, pp. 4
-
-
Dbouk, H.A.1
Mroue, R.M.2
El-Sabban, M.E.3
Talhouk, R.S.4
-
30
-
-
4944253254
-
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels
-
Turner, M. S. et al. Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels. Circ. Res. 95, 726-733 (2004).
-
(2004)
Circ. Res.
, vol.95
, pp. 726-733
-
-
Turner, M.S.1
-
31
-
-
84874066621
-
Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signalling
-
Mureli, S. et al. Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signalling. Am. J. Physiol. Heart Circ. Physiol. 304, H600-H609 (2013).
-
(2013)
Am. J. Physiol. Heart Circ. Physiol.
, vol.304
-
-
Mureli, S.1
-
32
-
-
0037040922
-
Transduction of cell survival signals by connexin-43 hemichannels
-
Plotkin, L. I., Manolagas, S. C. & Bellido, T. Transduction of cell survival signals by connexin-43 hemichannels. J. Biol. Chem. 277, 8648-8657 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8648-8657
-
-
Plotkin, L.I.1
Manolagas, S.C.2
Bellido, T.3
-
33
-
-
84864358695
-
Posttranslational modifications in connexins and pannexins
-
Johnstone, S. R., Billaud, M., Lohman, A. W., Taddeo, E. P. & Isakson, B. E. Posttranslational modifications in connexins and pannexins. J. Membr. Biol. 245, 319-332 (2012).
-
(2012)
J. Membr. Biol.
, vol.245
, pp. 319-332
-
-
Johnstone, S.R.1
Billaud, M.2
Lohman, A.W.3
Taddeo, E.P.4
Isakson, B.E.5
-
34
-
-
77953383616
-
Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors
-
Wu, Z. et al. Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors. Genes Cancer 1, 40-49 (2010).
-
(2010)
Genes Cancer
, vol.1
, pp. 40-49
-
-
Wu, Z.1
-
35
-
-
78649317469
-
Tamoxifen and ralox-ifene modulate gap junction coupling during early phases of retinoic acid-dependent neuronal differentiation of NTera2/D1 cells
-
Dahm, L., Klugmann, F., Gonzalez-Algaba, A. & Reuss, B. Tamoxifen and ralox-ifene modulate gap junction coupling during early phases of retinoic acid-dependent neuronal differentiation of NTera2/D1 cells. Cell Biol. Toxicol. 26, 579-591 (2010).
-
(2010)
Cell Biol. Toxicol.
, vol.26
, pp. 579-591
-
-
Dahm, L.1
Klugmann, F.2
Gonzalez-Algaba, A.3
Reuss, B.4
-
36
-
-
0029813625
-
Gap junction endocytosis and lysosomal degradation of connexin43-P2 in WB-F344 rat liver epithelial cells treated with DDT and lindane
-
Guan, X. & Ruch, R. J. Gap junction endocytosis and lysosomal degradation of connexin43-P2 in WB-F344 rat liver epithelial cells treated with DDT and lindane. Carcinogenesis 17, 1791-1798 (1996).
-
(1996)
Carcinogenesis
, vol.17
, pp. 1791-1798
-
-
Guan, X.1
Ruch, R.J.2
-
37
-
-
84875156443
-
Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells
-
Johnson, K. E. et al. Phosphorylation on Ser-279 and Ser-282 of connexin43 regulates endocytosis and gap junction assembly in pancreatic cancer cells. Mol. Biol. Cell 24, 715-733 (2013).
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 715-733
-
-
Johnson, K.E.1
-
38
-
-
84862611041
-
TBC1D14 regulates autophagosome formation via Rab11-and ULK1-positive recycling endosomes
-
Longatti, A. et al. TBC1D14 regulates autophagosome formation via Rab11-and ULK1-positive recycling endosomes. J. Cell Biol. 197, 659-675 (2012).
-
(2012)
J. Cell Biol.
, vol.197
, pp. 659-675
-
-
Longatti, A.1
-
39
-
-
7244255989
-
Role for Rab7 in maturation of late autophagic vacuoles
-
Jager, S. et al. Role for Rab7 in maturation of late autophagic vacuoles. J. Cell Sci. 117, 4837-4848 (2004).
-
(2004)
J. Cell Sci.
, vol.117
, pp. 4837-4848
-
-
Jager, S.1
-
40
-
-
64049113909
-
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex
-
Zhong, Y. et al. Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat. Cell Biol. 11, 468-476 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 468-476
-
-
Zhong, Y.1
-
41
-
-
64049086758
-
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
-
Matsunaga, K. et al. Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nat. Cell Biol. 11, 385-396 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 385-396
-
-
Matsunaga, K.1
-
42
-
-
0034282751
-
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
-
Gillooly, D. J. et al. Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells. EMBO J. 19, 4577-4588 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 4577-4588
-
-
Gillooly, D.J.1
-
44
-
-
65949095803
-
Autophagy regulates lipid metabolism
-
Singh, R. et al. Autophagy regulates lipid metabolism. Nature 458, 1131-1135 (2009).
-
(2009)
Nature
, vol.458
, pp. 1131-1135
-
-
Singh, R.1
-
45
-
-
1942470517
-
The effects of connexin phosphorylation on gap junctional communication
-
Lampe, P. D. & Lau, A. F. The effects of connexin phosphorylation on gap junctional communication. Int. J. Biochem. Cell Biol. 36, 1171-1186 (2004).
-
(2004)
Int. J. Biochem. Cell Biol.
, vol.36
, pp. 1171-1186
-
-
Lampe, P.D.1
Lau, A.F.2
-
46
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
Yamamoto, H. et al. Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J. Cell Biol. 198, 219-233 (2012).
-
(2012)
J. Cell Biol.
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
-
47
-
-
0028907907
-
Cardiac malformation in neonatal mice lacking connexin43
-
Reaume, A. G. et al. Cardiac malformation in neonatal mice lacking connexin43. Science 267, 1831-1834 (1995).
-
(1995)
Science
, vol.267
, pp. 1831-1834
-
-
Reaume, A.G.1
-
48
-
-
59249090846
-
Methods to monitor chaperone-mediated autophagy
-
Kaushik, S. & Cuervo, A. M. Methods to monitor chaperone-mediated autophagy. Methods Enzymol. 452, 297-324 (2009).
-
(2009)
Methods Enzymol.
, vol.452
, pp. 297-324
-
-
Kaushik, S.1
Cuervo, A.M.2
-
49
-
-
0020537510
-
Regulation of intracellular protein degradation in IMR-90 human diploid fibroblasts
-
Auteri, J. S., Okada, A., Bochaki, V. & Dice, J. F. Regulation of intracellular protein degradation in IMR-90 human diploid fibroblasts. J. Cell Physiol. 115, 159-166 (1983).
-
(1983)
J. Cell Physiol.
, vol.115
, pp. 159-166
-
-
Auteri, J.S.1
Okada, A.2
Bochaki, V.3
Dice, J.F.4
-
50
-
-
33746108329
-
Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
-
Tanida, I., Minematsu-Ikeguchi, N., Ueno, T. & Kominami, E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 1, 84-91 (2005).
-
(2005)
Autophagy
, vol.1
, pp. 84-91
-
-
Tanida, I.1
Minematsu-Ikeguchi, N.2
Ueno, T.3
Kominami, E.4
-
51
-
-
0028009409
-
Isolation of a matrix that binds medial Golgi enzymes
-
Slusarewicz, P., Nilsson, T., Hui, N., Watson, R. & Warren, G. Isolation of a matrix that binds medial Golgi enzymes. J. Cell Biol. 124, 405-413 (1994).
-
(1994)
J. Cell Biol.
, vol.124
, pp. 405-413
-
-
Slusarewicz, P.1
Nilsson, T.2
Hui, N.3
Watson, R.4
Warren, G.5
-
52
-
-
0020085949
-
Isolation of autophagic vacuoles from rat liver: Morphological and biochemical characterization
-
Marzella, L., Ahlberg, J. & Glaumann, H. Isolation of autophagic vacuoles from rat liver: Morphological and biochemical characterization. J. Cell Biol. 93, 144-154 (1982).
-
(1982)
J. Cell Biol.
, vol.93
, pp. 144-154
-
-
Marzella, L.1
Ahlberg, J.2
Glaumann, H.3
-
53
-
-
0028970286
-
Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments
-
Castellino, F. & Germain, R. N. Extensive trafficking of MHC class II-invariant chain complexes in the endocytic pathway and appearance of peptide-loaded class II in multiple compartments. Immunity 2, 73-88 (1995).
-
(1995)
Immunity
, vol.2
, pp. 73-88
-
-
Castellino, F.1
Germain, R.N.2
|