Lipids on trial: The search for the offending metabolite in Niemann-Pick type C disease

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Volumn 11, Issue 4, 2010, Pages 419-428

  Lloyd Evans, Emyr ^a   Platt, Frances M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cholesterol; Lysosomal calcium; Lysosomal storage disease; NPC1; NPC2; Sphingolipid; Sphingosine

Indexed keywords

CALCIUM; CHOLESTEROL; GLUCOSYLCERAMIDE; GLYCOSPHINGOLIPID; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEMBRANE PROTEIN; NIEMANN PICK TYPE C1 PROTEIN; NIEMANN PICK TYPE C2 PROTEIN; PERMEASE; PROTEIN KINASE C; RAB PROTEIN; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; UNCLASSIFIED DRUG; VIMENTIN;

CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CHOLESTEROL TRANSPORT; ENDOCYTOSIS; GENE MUTATION; HUMAN; LIPID STORAGE; LYSOSOME; LYSOSOME STORAGE DISEASE; NERVE DEGENERATION; NIEMANN PICK DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW;

ANIMALS; CARRIER PROTEINS; CHOLESTEROL; GLYCOPROTEINS; GLYCOSPHINGOLIPIDS; HUMANS; LIPID METABOLISM; LYSOSOMES; MEMBRANE GLYCOPROTEINS; MICE; NIEMANN-PICK DISEASE, TYPE C; SPHINGOSINE;

EID: 77951727293     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2010.01032.x     Document Type: Review

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