Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 42, 2013, Pages 17071-17076

  Tian, Yuan ^a   Chang, Jerry C ^a   Fan, Emily Y ^a   Flajolet, Marc ^a   Greengard, Paul ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Aggregate removal; Endocytosis; Trafficking

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN 2; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN CLEAVED C TERMINAL FRAGMENT; MICROTUBULE ASSOCIATED PROTEIN 1; PHOSPHATIDYLINOSITOL CLATHRIN ASSEMBLY LYMPHOID MYELOID LEUKEMIA PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PURIFICATION;

AGGREGATE REMOVAL; ENDOCYTOSIS; TRAFFICKING;

ADAPTOR PROTEIN COMPLEX 2; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AUTOPHAGY; HELA CELLS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MONOMERIC CLATHRIN ASSEMBLY PROTEINS; PROTEOLYSIS; RISK FACTORS;

EID: 84885736277     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315110110     Document Type: Article

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