A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation

Journal of Cell Biology

Volumn 172, Issue 5, 2006, Pages 733-745

  Levy, Jennifer R ^a   Sumner, Charlotte J ^b   Caviston, Juliane P ^a   Tokito, Mariko K ^a   Ranganathan, Srikanth ^b   Ligon, Lee A ^a   Wallace, Karen E ^a   LaMonte, Bernadette H ^a   Harmison, George G ^b   Puls, Imke ^b   Fischbeck, Kenneth H ^b   Holzbaur, Erika L F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSKELETON PROTEIN; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; NOCODAZOLE;

ARTICLE; CELL DEATH; CELL LINE; CYTOPLASM; DISEASE ASSOCIATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MITOSIS SPINDLE; MOLECULAR MECHANICS; MOTOR NEURON DISEASE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; DYNEIN ATPASE; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MITOCHONDRIA; MOTOR NEURONS; POINT MUTATION;

EUKARYOTA;

EID: 33644551565     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200511068     Document Type: Article

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