메뉴 건너뛰기




Volumn 65, Issue 12, 2013, Pages 1753-1756

Trehalose rescues Alzheimer's disease phenotypes in APP/PS1 transgenic mice

Author keywords

biological evaluation of natural products; drugs from natural sources; molecular and clinical pharmacology; whole body pharmacology

Indexed keywords

AMYLOID BETA PROTEIN; TREHALOSE;

EID: 84887984325     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12108     Document Type: Article
Times cited : (110)

References (10)
  • 1
    • 1642633757 scopus 로고    scopus 로고
    • Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease
    • et al.
    • Tanaka M, et al. Trehalose alleviates polyglutamine-mediated pathology in a mouse model of Huntington disease. Nat Med 2004; 10: 148-154.
    • (2004) Nat Med , vol.10 , pp. 148-154
    • Tanaka, M.1
  • 2
    • 77954955573 scopus 로고    scopus 로고
    • Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation
    • et al.
    • Rodríguez-Navarro JA, et al. Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation. Neurobiol Dis 2010; 39: 423-438.
    • (2010) Neurobiol Dis , vol.39 , pp. 423-438
    • Rodríguez-Navarro, J.A.1
  • 3
    • 7944233158 scopus 로고    scopus 로고
    • Cell biology of protein misfolding: The examples of Alzheimer's and Parkinson's diseases
    • Selkoe DJ,. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat Cell Biol 2004; 6: 1054-1061.
    • (2004) Nat Cell Biol , vol.6 , pp. 1054-1061
    • Selkoe, D.J.1
  • 4
    • 65849162974 scopus 로고    scopus 로고
    • Metabolites of cerebellar neurons and hippocampal neurons play opposite roles in pathogenesis of Alzheimer's disease
    • et al.
    • Du J, et al. Metabolites of cerebellar neurons and hippocampal neurons play opposite roles in pathogenesis of Alzheimer's disease. PLoS ONE 2009; 4: e5530.
    • (2009) PLoS ONE , vol.4
    • Du, J.1
  • 5
    • 69549086151 scopus 로고    scopus 로고
    • Effect of trehalose on amyloid beta (29-40)-membrane interaction
    • et al.: 085101-1-085101-8.
    • Reddy AS, et al. Effect of trehalose on amyloid beta (29-40)-membrane interaction. J Chem Phys 2009; 131: 085101-1-085101-8.
    • (2009) J Chem Phys , vol.131
    • Reddy, A.S.1
  • 6
    • 84862285881 scopus 로고    scopus 로고
    • Autophagic degradation of tau in primary neurons and its enhancement by trehalose
    • et al.
    • Krüger U, et al. Autophagic degradation of tau in primary neurons and its enhancement by trehalose. Neurobiol Aging 2012; 33: 2291-2305.
    • (2012) Neurobiol Aging , vol.33 , pp. 2291-2305
    • Krüger, U.1
  • 7
    • 79952104480 scopus 로고    scopus 로고
    • The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells
    • et al.
    • Casarejos MJ, et al. The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells. Neurochem Int 2011; 58: 512-520.
    • (2011) Neurochem Int , vol.58 , pp. 512-520
    • Casarejos, M.J.1
  • 8
    • 0034622244 scopus 로고    scopus 로고
    • Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes
    • et al.
    • Janus C, et al. Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes. Neurobiol Aging 2000a; 21: 541-549.
    • (2000) Neurobiol Aging , vol.21 , pp. 541-549
    • Janus, C.1
  • 9
    • 0034700471 scopus 로고    scopus 로고
    • A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
    • et al.
    • Janus C, et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 2000b; 408: 979-982.
    • (2000) Nature , vol.408 , pp. 979-982
    • Janus, C.1
  • 10
    • 34248181511 scopus 로고    scopus 로고
    • Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model
    • et al.
    • Roberson ED, et al. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science 2007; 316: 750-754.
    • (2007) Science , vol.316 , pp. 750-754
    • Roberson, E.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.