Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease

Brain

Volumn 134, Issue 5, 2011, Pages 1400-1415

  Nascimento Ferreira, Isabel ^a,b,c   Santos Ferreira, Tiago ^d   Sousa Ferreira, Lígia ^a,b   Auregan, Gwennaëlle ^c   Onofre, Isabel ^a,b   Alves, Sandro ^a,b,c   Dufour, Noëlle ^c   Colomer Gould, Veronica F ^e   Koeppen, Arnulf ^f   Déglon, Nicole ^c   Pereira De Almeida, Luís ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e DEPARTAMENTO DE FÍSICA   (Mexico)

^f ALBANY MEDICAL COLLEGE   (United States)

Author keywords

ataxin 3; autophagy; beclin 1; Machado Joseph disease; neuroprotection

Indexed keywords

ATAXIN 3; BECLIN 1;

ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; MACHADO JOSEPH DISEASE; MOUSE; NERVE CELL CULTURE; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM;

EID: 79957458183     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr047     Document Type: Article

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