Rapamycin alleviates toxicity of different aggregate-prone proteins

Human Molecular Genetics

Volumn 15, Issue 3, 2006, Pages 433-442

  Berger, Zdenek ^a,b   Ravikumar, Brinda ^a   Menzies, Fiona M ^a   Oroz, Lourdes Garcia ^a   Underwood, Benjamin R ^a,c   Pangalos, Menelas N ^e   Schmitt, Ina ^d   Wullner, Ullrich ^d   Evert, Bernd O ^d   O'Kane, Cahir J ^b   Rubinsztein, David C ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NORFOLK AND SUFFOLK NHS FOUNDATION TRUST   (United Kingdom)

^d UNIVERSITY HOSPITAL BONN   (Germany)

^e PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE; RAPAMYCIN; TAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DEGENERATIVE DISEASE; DROSOPHILA; DRUG POTENCY; ENZYME INHIBITION; FRONTOTEMPORAL DEMENTIA; GENE EXPRESSION; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AUTOPHAGY; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; DROSOPHILA; HUNTINGTON DISEASE; MUTATION; PEPTIDES; PROTEIN STRUCTURE, QUATERNARY; PROTEINS; SIROLIMUS; TAU PROTEINS; TRINUCLEOTIDE REPEAT EXPANSION;

ANIMALIA;

EID: 31544454404     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi458     Document Type: Article

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