The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation

Journal of Neuroscience

Volumn 34, Issue 4, 2014, Pages 1293-1305

  Wong, Yvette C ^a   Holzbaur, Erika L F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Autophagy; Axonal transport; Dynein; Huntingtin; Huntington's disease; Mitophagy

Indexed keywords

AUTOPHAGY; AXONAL TRANSPORT; DYNEIN; HUNTINGTIN; HUNTINGTON'S DISEASE; MITOPHAGY;

ANIMALS; AUTOPHAGY; AXONAL TRANSPORT; DISEASE MODELS, ANIMAL; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCK-IN TECHNIQUES; HUNTINGTON DISEASE; IMMUNOPRECIPITATION; MALE; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHAGOSOMES;

EID: 84892755229     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1870-13.2014     Document Type: Article

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