Impaired retrograde transport by the Dynein/Dynactin complex contributes to Tau-induced toxicity

Human Molecular Genetics

Volumn 24, Issue 13, 2015, Pages 3623-3637

  Butzlaff, Malte ^a,b   Hannan, Shabab B ^c   Karsten, Peter ^a   Lenz, Sarah ^a   Ng, Josephine ^c   Voßfeldt, Hannes ^a   Prüßing, Katja ^a   Pflanz, Ralf ^d   Schulz, Jörg B ^a,e   Rasse, Tobias ^c,f   Voigt, Aaron ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^e JARA TRANSLATIONAL BRAIN MEDICINE   (Germany)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; DYNEIN DYNACTIN COMPLEX; GLUTAMINE; MESSENGER RNA; TAR DNA BINDING PROTEIN; TAU PROTEIN; TUBULIN; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; TAU PROTEIN, DROSOPHILA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHROPOD LARVA; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE INTERACTION; GENE SILENCING; GENETIC SCREENING; HUMAN; LARVAL STAGE; MALE; MOLECULAR PATHOLOGY; NERVE FIBER MEMBRANE; NERVE FIBER TRANSPORT; NONHUMAN; ORTHOLOGY; PHENOTYPE; PHOTORECEPTOR; POSITION EFFECT VARIEGATION; PRIORITY JOURNAL; RETROGRADE NERVE FIBER TRANSPORT; TAUOPATHY; WILD TYPE; ALZHEIMER DISEASE; ANIMAL; AXON; DISEASE MODEL; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MISSENSE MUTATION; PROTEIN TRANSPORT; RNA INTERFERENCE;

DROSOPHILA MELANOGASTER;

ALZHEIMER DISEASE; ANIMALS; AXONS; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; DYNEINS; FEMALE; HUMANS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MUTATION, MISSENSE; PROTEIN TRANSPORT; RNA INTERFERENCE; TAU PROTEINS;

EID: 84936748562     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddv107     Document Type: Article

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