Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD

Autophagy

Volumn 12, Issue 7, 2016, Pages 1094-1104

  Goode, Alice ^a   Butler, Kevin ^a   Long, Jed ^a   Cavey, James ^a   Scott, Daniel ^a   Shaw, Barry ^a   Sollenberger, Jill ^a   Gell, Christopher ^a   Johansen, Terje ^b   Oldham, Neil J ^a   Searle, Mark S ^a   Layfield, Robert ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF TROMSØ   (Norway)

Author keywords

ALS; Atg8 LC3; autophagy; FTLD; LIR; SQSTM1 p62

Indexed keywords

GLUTATHIONE; LIPID; PROTEIN; SQSTM1 PROTEIN; UNCLASSIFIED DRUG; MAP1LC3B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; SEQUESTOSOME 1; SQSTM1 PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; AUTOPHAGY; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; FLUORESCENCE MICROSCOPY; FRONTOTEMPORAL DEMENTIA; HUMAN; ISOTHERMAL TITRATION CALORIMETRY; MISSENSE MUTATION; MOTONEURON; NITROGEN NUCLEAR MAGNETIC RESONANCE; NONHUMAN; PROTEIN PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; WESTERN BLOTTING; GENETICS; METABOLISM; MUTATION; PATHOLOGY; PHYSIOLOGY;

AMYOTROPHIC LATERAL SCLEROSIS; AUTOPHAGY; FRONTOTEMPORAL LOBAR DEGENERATION; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR NEURONS; MUTATION; SEQUESTOSOME-1 PROTEIN;

EID: 84966713295     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1170257     Document Type: Article

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