Regulation of intracellular accumulation of mutant huntingtin by beclin 1

Journal of Biological Chemistry

Volumn 281, Issue 20, 2006, Pages 14474-14485

  Shibata, Mamoru ^a,e   Lu, Tao ^a   Furuya, Tsuyoshi ^a   Degterev, Alexei ^a   Mizushima, Noboru ^c   Yoshimori, Tamotsu ^d   MacDonald, Marcy ^b   Yankner, Bruce ^a   Yuan, Junying ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d NATIONAL INSTITUTE OF GENETICS   (Japan)

^e KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; GENES; PATHOLOGY; PATIENT MONITORING; PROTEINS; TOXICITY;

BECLIN 1; INTRACELLULAR ACCUMULATION; MUTANT HUNTINGTIN;

DISEASES;

HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE; PROTEIN BECLIN 1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN TISSUE; HUNTINGTON CHOREA; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; TURNOVER TIME; WESTERN BLOTTING;

ADULT; AGED, 80 AND OVER; AGING; ANIMALS; APOPTOSIS REGULATORY PROTEINS; BRAIN; DISEASE PROGRESSION; GENE EXPRESSION REGULATION; HUMANS; MEMBRANE PROTEINS; MICE; MIDDLE AGED; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PROTEINS;

CITRUS MAXIMA;

EID: 33744916798     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600364200     Document Type: Article

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