Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure

Autophagy

Volumn 12, Issue 5, 2016, Pages 833-849

  Corcelle Termeau, Elisabeth ^a   Vindeløv, Signe Diness ^a   Hämälistö, Saara ^a   Mograbi, Baharia ^b   Keldsbo, Anne ^a   Bräsen, Jan Hinrich ^c   Favaro, Elena ^a   Adam, Dieter ^c   Szyniarowski, Piotr ^a,e   Hofman, Paul ^b,d   Krautwald, Stefan ^c   Farkas, Thomas ^a   Petersen, Nikolaj H T ^a,f   Rohde, Mikkel ^a   Linkermann, Andreas ^c   Jäättelä, Marja ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^b UNIVERSITY OF NICE SOPHIA ANTIPOLIS   (France)

^c UNIVERSITY OF KIEL   (Germany)

^d PASTEUR HOSPITAL   (France)

^e INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^f ORPHAZYME A S   (Denmark)

Author keywords

acid sphingomyelinase; ATG9A; autophagy; ischemia reperfusion injury; kidney; lysosome; Niemann Pick disease; sphingomyelin; trafficking

Indexed keywords

AUTOPHAGY PROTEIN 9A; CERAMIDE; PROTEIN DERIVATIVE; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; ASMASE, MOUSE; ATG9A PROTEIN, HUMAN; AUTOPHAGY RELATED PROTEIN; MEMBRANE PROTEIN; SMALL INTERFERING RNA; SPHINGOMYELIN PHOSPHODIESTERASE 1, HUMAN; TRANSFERRIN RECEPTOR; VESICULAR TRANSPORT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOLYSOSOME; AUTOPHAGOSOME; BIOGENESIS; CANCER CELL LINE; CELL MATURATION; CELL MEMBRANE; CELL ORGANELLE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; LIPID COMPOSITION; MALE; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN TRANSPORT; 129 MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOPHAGY; BREAST TUMOR; C57BL MOUSE; DEFICIENCY; ENDOSOME; FEMALE; GENETICS; KNOCKOUT MOUSE; MCF-7 CELL LINE; METABOLISM; NIEMANN PICK DISEASE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; AUTOPHAGOSOMES; AUTOPHAGY; AUTOPHAGY-RELATED PROTEINS; BREAST NEOPLASMS; CELL MEMBRANE; ENDOSOMES; FEMALE; FIBROBLASTS; HUMANS; MALE; MCF-7 CELLS; MEMBRANE PROTEINS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; NIEMANN-PICK DISEASE, TYPE A; PROTEIN TRANSPORT; RECEPTORS, TRANSFERRIN; RNA, SMALL INTERFERING; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS; VESICULAR TRANSPORT PROTEINS;

EID: 84963553795     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1159378     Document Type: Article

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