α-Synuclein impairs macroautophagy: Implications for Parkinson's disease

Journal of Cell Biology

Volumn 190, Issue 6, 2010, Pages 1023-1037

  Winslow, Ashley R ^a   Chen, Chien Wen ^a,b   Corrochano, Silvia ^c   Acevedo Arozena, Abraham ^c   Gordon, David E ^a   Peden, Andrew A ^a   Lichtenberg, Maike ^a   Menzies, Fiona M ^a   Ravikumar, Brinda ^a   Imarisio, Sara ^a,b   Brown, Steve ^c   O'Kane, Cahir J ^b   Rubinsztein, David C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MRC MAMMALIAN GENETICS UNIT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; AUTOPHAGY PROTEIN 9; CELL PROTEIN; RAB PROTEIN; RAB1 A PROTEIN; UNCLASSIFIED DRUG; LIGHT CHAIN 3, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MACROAUTOPHAGY; MOUSE; NONHUMAN; OMEGASOME; PARKINSON DISEASE; PHAGOSOME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; TRANSGENIC MOUSE; ANIMAL; BIOLOGICAL MODEL; DROSOPHILA MELANOGASTER; GENE SILENCING; GOLGI COMPLEX; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT; SECRETION (PROCESS); SECRETORY VESICLE; TUMOR CELL LINE;

MAMMALIA; MUS MUSCULUS;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; CELL LINE, TUMOR; DROSOPHILA MELANOGASTER; GENE KNOCKDOWN TECHNIQUES; GOLGI APPARATUS; HUMANS; MEMBRANE PROTEINS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MODELS, BIOLOGICAL; PARKINSON DISEASE; PHAGOSOMES; PROTEIN TRANSPORT; RAB1 GTP-BINDING PROTEINS; SECRETORY VESICLES;

EID: 77957189194     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.201003122     Document Type: Article

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