Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis

Nature Communications

Volumn 7, Issue , 2016, Pages

  Wu, Xiaoting ^a   Fleming, Angeleen ^a,b   Ricketts, Thomas ^a   Pavel, Mariana ^a   Virgin, Herbert ^c   Menzies, Fiona M ^a   Rubinsztein, David C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; NOTCH RECEPTOR; PROTEIN PRECURSOR; ATG16L1 PROTEIN, HUMAN; ATG16L1 PROTEIN, MOUSE; AUTOPHAGY RELATED PROTEIN; CARRIER PROTEIN; NOTCH1 PROTEIN, HUMAN; NOTCH1 PROTEIN, MOUSE; NOTCH1 RECEPTOR;

CELLS AND CELL COMPONENTS; GASTROENTERITIS; MENTAL HEALTH; MUTATION; NEUROLOGY; PHYSIOLOGICAL RESPONSE; PROTEIN; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATG16L1 GENE; AUTOPHAGOSOME; AUTOPHAGY; BONE MARROW; CELL FATE; CELL MATURATION; CELL MEMBRANE; CONTROLLED STUDY; EMBRYO; ENDOCYTOSIS; GENE; GENE MUTATION; INTESTINE; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; ENDOSOME; FLOW CYTOMETRY; GENE SILENCING; GENETICS; HEK293 CELL LINE; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LYSOSOME; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; STEM CELL;

ANIMALS; AUTOPHAGY; AUTOPHAGY-RELATED PROTEINS; CARRIER PROTEINS; CELL DIFFERENTIATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOSOMES; FLOW CYTOMETRY; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LYSOSOMES; MICE; NEURAL STEM CELLS; NEUROGENESIS; RECEPTOR, NOTCH1; STEM CELLS;

EID: 84957598643     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10533     Document Type: Article

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