Rapamycin treatment augments motor neuron degeneration in SOD1 G93A mouse model of amyotrophic lateral sclerosis

Autophagy

Volumn 7, Issue 4, 2011, Pages 412-425

  Zhang, Xiaojie ^a   Li, Liang ^a   Chen, Sheng ^a   Yang, Dehua ^a   Wang, Yi ^a   Zhang, Xin ^a   Wang, Zheng ^a   Le, Weidong ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

ALS; Apoptosis; Autophagy; Motor neuron degeneration; Protein aggregation

Indexed keywords

CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; PROTEIN; PROTEIN BAX; PROTEIN LC3 II; PROTEIN P62; PROTEIN SQSTM1; RAPAMYCIN; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DAMAGE; CELL VACUOLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELECTRON MICROSCOPY; ENZYME ACTIVATION; IMMUNOCHEMISTRY; MOTONEURON; MOUSE; MYELINATION; NERVE CELL DEGENERATION; NERVE FIBER DEGENERATION; NONHUMAN; PROTEIN AGGREGATION; RANDOMIZED CONTROLLED TRIAL; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL;

MUS;

EID: 79953647105     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.7.4.14541     Document Type: Article

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