Potential function for the Huntingtin protein as a scaffold for selective autophagy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 47, 2014, Pages 16889-16894

  Ochaba, Joseph ^a,b   Lukacsovich, Tamás ^b   Csikos, George ^c   Zheng, Shuqiu ^d   Margulis, Julia ^e   Salazar, Lisa ^a   Mao, Kai ^f   Lau, Alice L ^a   Yeung, Sylvia Y ^a   Humbert, Sandrine ^g   Saudou, Frédéric ^g   Klionsky, Daniel J ^f   Finkbeiner, Steven ^e   Zeitlin, Scott O ^d   Marsh, J Lawrence ^b   Housman, David E ^h   Thompson, Leslie M ^a,b   Steffan, Joan S ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^d UNIVERSITY OF VIRGINIA   (United States)

^e GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

^g INSTITUT CURIE   (France)

^h MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Huntingtin; Huntington disease; Neurodegeneration; Polyglutamine; Selective autophagy

Indexed keywords

AUTOPHAGY PROTEIN 11; HUNTINGTIN; POLYGLUTAMINE; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; HUNTINGTIN PROTEIN, DROSOPHILA; MICROTUBULE ASSOCIATED PROTEIN;

ARTICLE; AUTOPHAGOSOME; AUTOSOMAL DOMINANT DISORDER; CARBOXY TERMINAL SEQUENCE; DEGENERATIVE DISEASE; DROSOPHILA; HUMAN; HUNTINGTON CHOREA; MITOPHAGY; NEUROLOGIC DISEASE; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; SELECTIVE AUTOPHAGY; STARVATION; YEAST; ANIMAL; AUTOPHAGY; GENETICS; MOUSE; PHYSIOLOGY; TRANSGENIC ANIMAL;

MAMMALIA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; AUTOPHAGY; DROSOPHILA; MICE; MICROTUBULE-ASSOCIATED PROTEINS;

EID: 84912100068     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420103111     Document Type: Article

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