The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

EMBO Journal

Volumn 35, Issue 15, 2016, Pages 1656-1676

  Webster, Christopher P ^a   Smith, Emma F ^a   Bauer, Claudia S ^a   Moller, Annekathrin ^a   Hautbergue, Guillaume M ^a   Ferraiuolo, Laura ^a   Myszczynska, Monika A ^a   Higginbottom, Adrian ^a   Walsh, Matthew J ^a   Whitworth, Alexander J ^b,d   Kaspar, Brian K ^c   Meyer, Kathrin ^c   Shaw, Pamela J ^a   Grierson, Andrew J ^a   De Vos, Kurt J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

amyotrophic lateral sclerosis; autophagy; C9orf72; frontotemporal dementia; Rab GTPase

Indexed keywords

ALPHA TUBULIN; BAFILOMYCIN A1; C9ORF72 PROTEIN; ENZYME; MICRORNA; PROTEIN P62; RAB1A PROTEIN; SMALL INTERFERING RNA; UNC 51 LIKE KINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BRAIN CELL; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; HAPLOINSUFFICIENCY; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; MAMMAL CELL; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

EID: 84980410069     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201694401     Document Type: Article

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