메뉴 건너뛰기




Volumn 4, Issue , 2013, Pages

Overexpression of Atg5 in mice activates autophagy and extends lifespan

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5;

EID: 84883114523     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms3300     Document Type: Article
Times cited : (561)

References (57)
  • 1
    • 56349168452 scopus 로고    scopus 로고
    • Autophagy and ageing: Keeping that old broom working
    • Cuervo, A. M. Autophagy and ageing: keeping that old broom working. Trends Genet. 24, 604-612 (2008).
    • (2008) Trends Genet. , vol.24 , pp. 604-612
    • Cuervo, A.M.1
  • 2
    • 35948982621 scopus 로고    scopus 로고
    • The role of autophagy in aging: Its essential part in the anti-aging mechanism of caloric restriction
    • DOI 10.1196/annals.1396.020, Healthy Aging and Longevity: Third International Conference
    • Bergamini, E., Cavallini, G., Donati, A. & Gori, Z. The role of autophagy in ageing: its essential part in the anti-ageing mechanism of caloric restriction. Ann. N Y Acad. Sci. 1114, 69-78 (2007). (Pubitemid 350070387)
    • (2007) Annals of the New York Academy of Sciences , vol.1114 , pp. 69-78
    • Bergamini, E.1    Cavallini, G.2    Donati, A.3    Gori, Z.4
  • 3
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • DOI 10.1038/nrm1666
    • Baehrecke, E. H. Autophagy: dual roles in life and death? Nat. Rev. Mol. Cell Biol. 6, 505-510 (2005). (Pubitemid 40780562)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 4
    • 57649234905 scopus 로고    scopus 로고
    • Autophagy genes and ageing
    • Vellai, T. Autophagy genes and ageing. Cell Death Differ. 1, 94-102 (2009).
    • (2009) Cell Death Differ. , vol.1 , pp. 94-102
    • Vellai, T.1
  • 5
    • 78649704325 scopus 로고    scopus 로고
    • Autophagy and metabolism
    • Rabinowitz, J. D. & White, E. Autophagy and metabolism. Science 330, 1344-1348 (2010).
    • (2010) Science , vol.330 , pp. 1344-1348
    • Rabinowitz, J.D.1    White, E.2
  • 7
    • 33846210657 scopus 로고    scopus 로고
    • Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans
    • Jia, K., Hart, A. C. & Levine, B. Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans. Autophagy 3, 21-25 (2007). (Pubitemid 46100705)
    • (2007) Autophagy , vol.3 , Issue.1 , pp. 21-25
    • Jia, K.1    Hart, A.C.2    Levine, B.3
  • 8
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and life-span extension in C. Elegans
    • DOI 10.1126/science.1087782
    • Meléndez, A. et al. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301, 1387-1391 (2003). (Pubitemid 37075816)
    • (2003) Science , vol.301 , Issue.5638 , pp. 1387-1391
    • Melendez, A.1    Talloczy, Z.2    Seaman, M.3    Eskelinen, E.-L.4    Hall, D.H.5    Levine, B.6
  • 9
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
    • DOI 10.1016/j.cub.2004.03.059, PII S0960982204002386
    • Kapahi, P. et al. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr. Biol. 14, 885-890 (2004). (Pubitemid 38800910)
    • (2004) Current Biology , vol.14 , Issue.10 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 10
    • 72649091698 scopus 로고    scopus 로고
    • Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
    • Bjedov, I. et al. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metab. 11, 35-46 (2010).
    • (2010) Cell Metab. , vol.11 , pp. 35-46
    • Bjedov, I.1
  • 12
    • 70449529855 scopus 로고    scopus 로고
    • Induction of autophagy by spermidine promotes longevity
    • Eisenberg, T. et al. Induction of autophagy by spermidine promotes longevity. Nat. Cell Biol. 11, 1305-1314 (2009).
    • (2009) Nat. Cell Biol. , vol.11 , pp. 1305-1314
    • Eisenberg, T.1
  • 13
    • 67650944993 scopus 로고    scopus 로고
    • Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    • Harrison, D. E. et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature 460, 392-395 (2009).
    • (2009) Nature , vol.460 , pp. 392-395
    • Harrison, D.E.1
  • 14
    • 0037005262 scopus 로고    scopus 로고
    • Autophagosome formation in mammalian cells
    • DOI 10.1247/csf.27.421
    • Mizushima, N., Ohsumi, Y. & Yoshimori, T. Autophagosome formation in mammalian cells. Cell Struct. Funct. 6, 421-429 (2002). (Pubitemid 36267711)
    • (2002) Cell Structure and Function , vol.27 , Issue.6 , pp. 421-429
    • Mizushima, N.1    Ohsumi, Y.2    Yoshimori, T.3
  • 16
    • 33745192802 scopus 로고    scopus 로고
    • Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
    • Hara, T. et al. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441, 885-889 (2006).
    • (2006) Nature , vol.441 , pp. 885-889
    • Hara, T.1
  • 17
    • 79955377420 scopus 로고    scopus 로고
    • Autophagy-deficient mice develop multiple liver tumors
    • Takamura, A. et al. Autophagy-deficient mice develop multiple liver tumors. Genes Dev. 25, 795-800 (2011).
    • (2011) Genes Dev. , vol.25 , pp. 795-800
    • Takamura, A.1
  • 18
    • 74949118681 scopus 로고    scopus 로고
    • The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
    • Rouschop, K. M. et al. The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J. Clin. Invest. 120, 127-241 (2010).
    • (2010) J. Clin. Invest. , vol.120 , pp. 127-241
    • Rouschop, K.M.1
  • 19
    • 77956274584 scopus 로고    scopus 로고
    • Genome-wide analysis reveals mechanisms modulating autophagy in normal brain ageing and in Alzheimer's disease
    • Lipinski, M. M. et al. Genome-wide analysis reveals mechanisms modulating autophagy in normal brain ageing and in Alzheimer's disease. Proc. Natl Acad. Sci. USA 107, 14164-14169 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 14164-14169
    • Lipinski, M.M.1
  • 22
    • 84934440488 scopus 로고    scopus 로고
    • Autophagosomes in GFP-LC3 transgenic mice
    • Mizushima, N. & Kuma, A. Autophagosomes in GFP-LC3 transgenic mice. Methods Mol. Biol. 445, 119-124 (2008).
    • (2008) Methods Mol. Biol. , vol.445 , pp. 119-124
    • Mizushima, N.1    Kuma, A.2
  • 23
    • 77952863834 scopus 로고    scopus 로고
    • Genetic control of de novo lipogenesis: Role in diet-induced obesity
    • Strable, M. S. & Ntambi, J. M. Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit. Rev. Biochem. Mol. Biol. 45, 199-214 (2010).
    • (2010) Crit. Rev. Biochem. Mol. Biol. , vol.45 , pp. 199-214
    • Strable, M.S.1    Ntambi, J.M.2
  • 24
    • 84863676903 scopus 로고    scopus 로고
    • Endothelial cells, cholesterol, cytokines, and ageing
    • Tetè, S. et al. Endothelial cells, cholesterol, cytokines, and ageing. Int. J. Immunopathol. Pharmacol. 2, 355-363 (2012).
    • (2012) Int. J. Immunopathol. Pharmacol. , vol.2 , pp. 355-363
    • Tetè, S.1
  • 25
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • DOI 10.1038/27376
    • Friedman, J. M. & Halaas, J. L. Leptin and the regulation of body weight in mammals. Nature 395, 763-770 (1998). (Pubitemid 28485436)
    • (1998) Nature , vol.395 , Issue.6704 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 26
    • 84863230675 scopus 로고    scopus 로고
    • Age-dependent and tissue-related glutathione redox status in a mouse model of Alzheimer's disease
    • Zhang, C., Rodriguez, C., Spaulding, J., Aw, T. Y. & Feng, J. Age-dependent and tissue-related glutathione redox status in a mouse model of Alzheimer's disease. J. Alzheimers Dis. 28, 655-666 (2012).
    • (2012) J. Alzheimers Dis. , vol.28 , pp. 655-666
    • Zhang, C.1    Rodriguez, C.2    Spaulding, J.3    Aw, T.Y.4    Feng, J.5
  • 28
    • 77951217000 scopus 로고    scopus 로고
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class i and III phosphoinositide 3-kinase
    • Wu, Y. T. et al. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J. Biol. Chem. 285, 10850-10861 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 10850-10861
    • Wu, Y.T.1
  • 29
    • 0025925091 scopus 로고
    • +-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells
    • Yoshimori, T. Bafilomycin A1, a specific inhibitor of vacuolar-type H -ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells. J. Biol. Chem. 15, 17707-17712 (1991). (Pubitemid 21907995)
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.26 , pp. 17707-17712
    • Yoshimori, T.1    Yamamoto, A.2    Moriyama, Y.3    Futai, M.4    Tashiro, Y.5
  • 30
    • 79960042882 scopus 로고    scopus 로고
    • Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment
    • Dasuri, K. et al. Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment. Free Rad. Biol. Med. 49, 1290-1297 (2010).
    • (2010) Free Rad. Biol. Med. , vol.49 , pp. 1290-1297
    • Dasuri, K.1
  • 31
    • 0034545719 scopus 로고    scopus 로고
    • Quantification and significance of protein oxidation in biological samples
    • Emily, S. Quantification and significance of protein oxidation in biological samples. Drug. Metab. Rev. 32, 307-326 (2000).
    • (2000) Drug. Metab. Rev. , vol.32 , pp. 307-326
    • Emily, S.1
  • 32
    • 0034613294 scopus 로고    scopus 로고
    • Age-related decline in chaperone-mediated autophagy
    • Cuervo, A. M. & Dice, J. F. Age-related decline in chaperone-mediated autophagy. J. Biol. Chem. 275, 31505-31513 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 31505-31513
    • Cuervo, A.M.1    Dice, J.F.2
  • 34
    • 77956416339 scopus 로고    scopus 로고
    • Autophagy in mammalian development and differentiation
    • Mizushima, N. & Levine, B. Autophagy in mammalian development and differentiation. Nat. Cell Biol. 9, 823-830 (2010).
    • (2010) Nat. Cell Biol. , vol.9 , pp. 823-830
    • Mizushima, N.1    Levine, B.2
  • 37
    • 57549094368 scopus 로고    scopus 로고
    • The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice
    • Sou, Y. S. et al. The Atg8 conjugation system is indispensable for proper development of autophagic isolation membranes in mice. Mol. Biol. Cell 19, 4762-4775 (2008).
    • (2008) Mol. Biol. Cell , vol.19 , pp. 4762-4775
    • Sou, Y.S.1
  • 41
    • 73949083594 scopus 로고    scopus 로고
    • Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response
    • Saitoh, T. et al. Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proc. Natl Acad. Sci. USA 106, 20842-20846 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 20842-20846
    • Saitoh, T.1
  • 42
    • 56249090667 scopus 로고    scopus 로고
    • Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1b production
    • Saitoh, T. et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1b production. Nature 456, 264-268 (2008).
    • (2008) Nature , vol.456 , pp. 264-268
    • Saitoh, T.1
  • 43
    • 33749562122 scopus 로고    scopus 로고
    • Role of FIP200 in cardiac and liver development and its regulation of TNFα and TSC-mTOR signaling pathways
    • DOI 10.1083/jcb.200604129
    • Gan, B. et al. Role of FIP200 in cardiac and liver development and its regulation of TNFa and TSC-mTOR signaling pathways. J. Cell Biol. 175, 121-133 (2006). (Pubitemid 44537204)
    • (2006) Journal of Cell Biology , vol.175 , Issue.1 , pp. 121-133
    • Gan, B.1    Peng, X.2    Nagy, T.3    Alcaraz, A.4    Gu, H.5    Guan, J.-L.6
  • 44
    • 36448968532 scopus 로고    scopus 로고
    • FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
    • DOI 10.1016/j.cmet.2007.11.004, PII S1550413107003397
    • Zhao, J. et al. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab. 6, 472-483 (2007). (Pubitemid 350163056)
    • (2007) Cell Metabolism , vol.6 , Issue.6 , pp. 472-483
    • Zhao, J.1    Brault, J.J.2    Schild, A.3    Cao, P.4    Sandri, M.5    Schiaffino, S.6    Lecker, S.H.7    Goldberg, A.L.8
  • 46
    • 67349273985 scopus 로고    scopus 로고
    • SIRT1: Regulation of longevity via autophagy
    • Salminen, A. & Kaarniranta, K. SIRT1: regulation of longevity via autophagy. Cell Signal 21, 1356-1360 (2009).
    • (2009) Cell Signal , vol.21 , pp. 1356-1360
    • Salminen, A.1    Kaarniranta, K.2
  • 47
    • 70349669095 scopus 로고    scopus 로고
    • Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
    • Selman, C. et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science 326, 140-144 (2009).
    • (2009) Science , vol.326 , pp. 140-144
    • Selman, C.1
  • 48
    • 20144381544 scopus 로고    scopus 로고
    • Essential roles of Atg5 and FADD in autophagic cell death: Dissection of autophagic cell death into vacuole formation and cell death
    • Pyo, J. O. et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J. Biol. Chem. 280, 20722-20729 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 20722-20729
    • Pyo, J.O.1
  • 51
    • 14844293962 scopus 로고    scopus 로고
    • The role of insulin and IGF-1 signaling in longevity
    • DOI 10.1007/s00018-004-4297-y
    • Katic, M. & Kahn, C. R. The role of insulin and IGF-1 signaling in longevity. Cell Mol. Life Sci. 62, 320-343 (2005). (Pubitemid 40379247)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.3 , pp. 320-343
    • Katic, M.1    Kahn, C.R.2
  • 52
    • 0037312020 scopus 로고    scopus 로고
    • How does calorie restriction work?
    • DOI 10.1101/gad.1052903
    • Koubova, J. & Guarente, L. How does calorie restriction work? Genes Dev. 17, 313-321 (2003). (Pubitemid 36182188)
    • (2003) Genes and Development , vol.17 , Issue.3 , pp. 313-321
    • Koubova, J.1    Guarente, L.2
  • 54
    • 0018854538 scopus 로고
    • Glutathione contents of tissues in the ageing mouse
    • George, A. H. & Calvin, A. L. Glutathione contents of tissues in the ageing mouse. Biochem. J. 188, 25-30 (1980).
    • (1980) Biochem. J. , vol.188 , pp. 25-30
    • George, A.H.1    Calvin, A.L.2
  • 55
    • 52249115856 scopus 로고    scopus 로고
    • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
    • Busche, M. A. et al. Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 321, 1686-1689 (2008).
    • (2008) Science , vol.321 , pp. 1686-1689
    • Busche, M.A.1
  • 57
    • 0034545719 scopus 로고    scopus 로고
    • Quantification and significance of protein oxidation in biological samples
    • DOI 10.1081/DMR-100102336
    • Shacter, E. Quantification and significance of protein oxidation in biological samples. Drug Metab. Rev. 32, 307-326 (2000). (Pubitemid 32001909)
    • (2000) Drug Metabolism Reviews , vol.32 , Issue.3-4 , pp. 307-326
    • Shacter, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.