-
1
-
-
0032902974
-
Oxidative alterations in Alzheimer's disease
-
MARKESBERY WR, CARNEY JM: Oxidative alterations in Alzheimer's disease. Brain Pathol. (1999) 9:133-146.
-
(1999)
Brain Pathol
, vol.9
, pp. 133-146
-
-
Markesbery, W.R.1
Carney, J.M.2
-
2
-
-
0035054836
-
Copernicus revisited: Amyloid β in Alzheimer's disease
-
JOSEPH J, SHUKITT-HALE B, DENISOVA NA, MARTIN A, PERRY G, SMITH MA: Copernicus revisited: amyloid β in Alzheimer's disease. Neurobiol. Aging (2001) 22:131-146.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 131-146
-
-
Joseph, J.1
Shukitt-hale, B.2
Denisova, N.A.3
Martin, A.4
Perry, G.5
Smith, M.A.6
-
3
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
-
ZHANG Y, DAWSON VL, DAWSON TM: Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol. Dis. (2000) 7:240-250.
-
(2000)
Neurobiol. Dis
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
4
-
-
0034009915
-
Influence of neurotoxins and oxidative stress on the onset and progression of Parkinson's disease
-
FOLEY P, RIEDERER P: Influence of neurotoxins and oxidative stress on the onset and progression of Parkinson's disease. J. Neurol. (2000) 247(Suppl. 2):II82-II94.
-
(2000)
J. Neurol
, vol.247
, Issue.SUPPL. 2
-
-
Foley, P.1
Riederer, P.2
-
6
-
-
0032949602
-
Oxidative stress and motor neurone disease
-
COOKSON MR, SHAW PJ: Oxidative stress and motor neurone disease. Brain Pathol. (1999) 9:165-186.
-
(1999)
Brain Pathol
, vol.9
, pp. 165-186
-
-
Cookson, M.R.1
Shaw, P.J.2
-
7
-
-
0035003439
-
Chemistry and biochemistry of oxidative stress in neurodegenerative disease
-
SAYRE LM, SMITH MA, PERRY G: Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. (2001) 8:721-738.
-
(2001)
Curr. Med. Chem
, vol.8
, pp. 721-738
-
-
Sayre, L.M.1
Smith, M.A.2
Perry, G.3
-
8
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
-
GIASSON BI, DUDA JE, MURRAY I et al.: Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions. Science (2000) 290:985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.3
-
9
-
-
0035887860
-
Induction of α-synuclein aggregation by intracellular nitrative insult
-
PAXINOU E, CHEN Q, WEISSE M et al.: Induction of α-synuclein aggregation by intracellular nitrative insult. J. Neurosci. (2001) 21:8053-8061.
-
(2001)
J. Neurosci
, vol.21
, pp. 8053-8061
-
-
Paxinou, E.1
Chen, Q.2
Weisse, M.3
-
10
-
-
0033771793
-
Is there a cause-and-effect relationship between a synuclein fibrillization and Parkinson's disease?
-
GOLDBERG MS, LANSBURY PT. Is there a cause-and-effect relationship between a synuclein fibrillization and Parkinson's disease? Nat. Cell Biol. (2000) 2:E115-E119.
-
(2000)
Nat. Cell Biol
, vol.2
-
-
Goldberg, M.S.1
Lansbury, P.T.2
-
11
-
-
0035951759
-
Biochemistry of neurodegeneration
-
PERRY G, AVILA J, ESPEY MG, WINK DA, ATWOOD CS, SMITH MA: Biochemistry of neurodegeneration. Science (2001) 291:595-596.
-
(2001)
Science
, vol.291
, pp. 595-596
-
-
Perry, G.1
Avila, J.2
Espey, M.G.3
Wink, D.A.4
Atwood, C.S.5
Smith, M.A.6
-
12
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer's disease
-
SMITH MA, HARRIS PL, SAYRE LM, BECKMAN JS, PERRY G: Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. (1997) 17:2653-2657.
-
(1997)
J. Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
13
-
-
0033520461
-
Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
-
WALSH DM, HARTLEY DM, KUSUMOTO Y et al.: Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J. Biol. Chem. (1999) 274:25945-25952.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
-
14
-
-
0034746895
-
Oxidation of Aβ and plaque biogenesis in Alzheimer's disease and Down's syndrome
-
HEAD E, GARZON-RODRIGUEZ W, JOHNSON JK, LOTT IT, COTMAN CW, GLABE C: Oxidation of Aβ and plaque biogenesis in Alzheimer's disease and Down's syndrome. Neurobiol. Dis. (2001) 8:792-806.
-
(2001)
Neurobiol. Dis
, vol.8
, pp. 792-806
-
-
Head, E.1
Garzon-rodriguez, W.2
Johnson, J.K.3
Lott, I.T.4
Cotman, C.W.5
Glabe, C.6
-
15
-
-
0029114196
-
Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments
-
SCHWEERS O, MANDELKOW EM, BIERNAT J, MANDELKOW E: Oxidation of cysteine-322 in the repeat domain of microtubule-associated protein tau controls the in vitro assembly of paired helical filaments. Proc. Natl. Acad. Sci. USA (1995) 92:8463-8467.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8463-8467
-
-
Schweers, O.1
Mandelkow, E.M.2
Biernat, J.3
Mandelkow, E.4
-
16
-
-
0035112495
-
Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures
-
LOVELL MA, XIE C, MARKESBERY WR: Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures. Neurobiol. Aging (2001) 22:187-194.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 187-194
-
-
Lovell, M.A.1
Xie, C.2
Markesbery, W.R.3
-
17
-
-
0034141819
-
Analysis of free and protein-bound nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts
-
FROST MT, HALLIWELL B, MOORE KP: Analysis of free and protein-bound nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts. Biochem. J. (2000) 345:453-458.
-
(2000)
Biochem. J
, vol.345
, pp. 453-458
-
-
Frost, M.T.1
Halliwell, B.2
Moore, K.P.3
-
18
-
-
0033565994
-
Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: Measurement, mechanism and the effects of nutrition
-
HALLIWELL B: Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and the effects of nutrition. Mutat. Res. (1999) 443:37-52.
-
(1999)
Mutat. Res
, vol.443
, pp. 37-52
-
-
Halliwell, B.1
-
19
-
-
0033758324
-
Neuronal oxidative stress precedes amyloid-β deposition in Down's syndrome
-
NUNOMURA A, PERRY G, PAPPOLLA MA et al.: Neuronal oxidative stress precedes amyloid-β deposition in Down's syndrome. J. Neuropathol. Exp. Neurol. (2000) 59:1011-1017.
-
(2000)
J. Neuropathol. Exp. Neurol
, vol.59
, pp. 1011-1017
-
-
Nunomura, A.1
Perry, G.2
Pappolla, M.A.3
-
20
-
-
0035875690
-
Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
-
PRATICO D, URYU K, LEIGHT S, TROJANOSWKI JQ, LEE VM: Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J. Neurosci. (2001) 21:4183-4187.
-
(2001)
J. Neurosci
, vol.21
, pp. 4183-4187
-
-
Pratico, D.1
Uryu, K.2
Leight, S.3
Trojanoswki, J.Q.4
Lee, V.M.5
-
21
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
BETARBET R, SHERER TB, MACKENZIE G, GARCIA-OSUNA M, PANOV AV, GREENAMYRE JT. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. (2000) 3:1301-1306.
-
(2000)
Nat. Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
Mackenzie, G.3
Garcia-osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
22
-
-
0034676997
-
MPTP induces α-synuclein aggregation in the substantia nigra of baboons
-
KOWALL NW, HANTRAYE P, BROUILLET E, BEAL MF, MCKEE AC, FERRANTE RJ: MPTP induces α-synuclein aggregation in the substantia nigra of baboons. Neuroreport (2000) 11:211-213.
-
(2000)
Neuroreport
, vol.11
, pp. 211-213
-
-
Kowall, N.W.1
Hantraye, P.2
Brouillet, E.3
Beal, M.F.4
Mckee, A.C.5
Ferrante, R.J.6
-
23
-
-
0034660457
-
Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease
-
FERRANTE RJ, ANDREASSEN OA, JENKINS BG et al.: Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease. J. Neurosci. (2000) 20: 4389-4397.
-
(2000)
J. Neurosci
, vol.20
, pp. 4389-4397
-
-
Ferrante, R.J.1
Andreassen, O.A.2
Jenkins, B.G.3
-
24
-
-
0027354319
-
Free radical involvement in aging. Pathophysiology and therapeutic implications
-
HARMAN D: Free radical involvement in aging. Pathophysiology and therapeutic implications. Drugs Aging (1993) 3:60-80.
-
(1993)
Drugs Aging
, vol.3
, pp. 60-80
-
-
Harman, D.1
-
25
-
-
0031984218
-
Extending the functional life span
-
HARMAN D: Extending the functional life span. Exp. Gerontol. (1998) 33:95-112.
-
(1998)
Exp. Gerontol
, vol.33
, pp. 95-112
-
-
Harman, D.1
-
26
-
-
0031916984
-
The free radical theory of aging matures
-
BECKMAN KB, AMES BN: The free radical theory of aging matures. Physiol. Rev. (1998) 78:547-581.
-
(1998)
Physiol. Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
27
-
-
0029920370
-
Genetic analysis of ageing: Role of oxidative damage and environmental stresses
-
MARTIN GM, AUSTAD SN, JOHNSON TE: Genetic analysis of ageing: role of oxidative damage and environmental stresses. Nat. Genet. (1996) 13:25-34.
-
(1996)
Nat. Genet
, vol.13
, pp. 25-34
-
-
Martin, G.M.1
Austad, S.N.2
Johnson, T.E.3
-
28
-
-
0029761483
-
A hypothesis on the pathogenesis of Alzheimer's disease
-
HARMAN D: A hypothesis on the pathogenesis of Alzheimer's disease. Ann. NY Acad. Sci. (1996) 786:152-168.
-
(1996)
Ann. NY Acad. Sci
, vol.786
, pp. 152-168
-
-
Harman, D.1
-
29
-
-
0027209389
-
Strategies of antioxidant defense
-
SIES H: Strategies of antioxidant defense. Eur. J. Biochem. (1993) 215:213-219.
-
(1993)
Eur. J. Biochem
, vol.215
, pp. 213-219
-
-
Sies, H.1
-
30
-
-
0033965893
-
The allosteric ATP-inhibition of cytochrome c oxidase activity is reversibly switched on by cAMP-dependent phosphorylation
-
BENDER E, KADENBACH B: The allosteric ATP-inhibition of cytochrome c oxidase activity is reversibly switched on by cAMP-dependent phosphorylation. FEBS Lett. (2000) 466:130-134.
-
(2000)
FEBS Lett
, vol.466
, pp. 130-134
-
-
Bender, E.1
Kadenbach, B.2
-
31
-
-
0343714594
-
Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase
-
KADENBACH B, HUTTEMANN M, ARNOLD S, LEE I, BENDER E: Mitochondrial energy metabolism is regulated via nuclear-coded subunits of cytochrome c oxidase. Free Radic. Biol. Med. (2000) 29:211-221.
-
(2000)
Free Radic. Biol. Med
, vol.29
, pp. 211-221
-
-
Kadenbach, B.1
Huttemann, M.2
Arnold, S.3
Lee, I.4
Bender, E.5
-
32
-
-
15344342522
-
Micronutrients prevent cancer and delay aging
-
AMES BN: Micronutrients prevent cancer and delay aging. Toxicol. Lett. (1998) 102 103:5-18.
-
(1998)
Toxicol. Lett
, vol.102-103
, pp. 5-18
-
-
Ames, B.N.1
-
33
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen
-
BOVERIS A, CHANCE B: The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem. J. (1973) 134:707-716.
-
(1973)
Biochem. J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
34
-
-
0034456720
-
Mitochondrial production of hydrogen peroxide: Regulation by nitric oxide and the role of ubisemiquinone
-
BOVERIS A, CADENAS E: Mitochondrial production of hydrogen peroxide: regulation by nitric oxide and the role of ubisemiquinone. IUBMB Life (2000) 50:245-250.
-
(2000)
IUBMB Life
, vol.50
, pp. 245-250
-
-
Boveris, A.1
Cadenas, E.2
-
35
-
-
0031729302
-
Poor recovery of mitochondrial redox state in CA1 after transient forebrain ischemia in gerbils
-
SHIINO A, MATSUDA M, HANDA J, CHANCE B: Poor recovery of mitochondrial redox state in CA1 after transient forebrain ischemia in gerbils. Stroke (1998) 29:2421-2424.
-
(1998)
Stroke
, vol.29
, pp. 2421-2424
-
-
Shiino, A.1
Matsuda, M.2
Handa, J.3
Chance, B.4
-
36
-
-
0035234813
-
A mitochondrial paradigm for degenerative diseases and ageing
-
WALLACE DC: A mitochondrial paradigm for degenerative diseases and ageing. Novartis Found. Symp. (2001) 235:247-263.
-
(2001)
Novartis Found. Symp
, vol.235
, pp. 247-263
-
-
Wallace, D.C.1
-
37
-
-
0032504710
-
Mitochondrial dysfunction in neurodegenerative diseases
-
BEAL MF: Mitochondrial dysfunction in neurodegenerative diseases. Biochim. Biophys. Acta (1998) 1366:211-223.
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 211-223
-
-
Beal, M.F.1
-
38
-
-
0032904412
-
An evaluation of the role of mitochondria in neurodegenerative diseases: Mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration
-
CASSARINO DS, BENNETT JP: An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res. Brain Res. Rev. (1999) 29:1-25.
-
(1999)
Brain Res. Brain Res. Rev
, vol.29
, pp. 1-25
-
-
Cassarino, D.S.1
Bennett, J.P.2
-
39
-
-
0033496016
-
Excitotoxins in neuronal apoptosis and necrosis
-
NICOTERA P, LIPTON SA: Excitotoxins in neuronal apoptosis and necrosis. J. Cereb. Blood Flow Metab. (1999) 19:583-591.
-
(1999)
J. Cereb. Blood Flow Metab
, vol.19
, pp. 583-591
-
-
Nicotera, P.1
Lipton, S.A.2
-
40
-
-
0032704101
-
Antioxidants, oxidative stress, and degenerative neurological disorders
-
FLOYD RA: Antioxidants, oxidative stress, and degenerative neurological disorders. Proc. Soc. Exp. Biol. Med. (1999) 222:236-245.
-
(1999)
Proc. Soc. Exp. Biol. Med
, vol.222
, pp. 236-245
-
-
Floyd, R.A.1
-
41
-
-
17344390525
-
N-t-Butyl hydroxylamine, a hydrolysis product of α-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts
-
ATAMNA H, PALER-MARTINEZ A, AMES BN: N-t-Butyl hydroxylamine, a hydrolysis product of α-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts. J. Biol. Chem. (2000) 275:6741-6748.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 6741-6748
-
-
Atamna, H.1
Paler-martinez, A.2
Ames, B.N.3
-
42
-
-
0034806211
-
N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro
-
ATAMNA H, ROBINSON C, INGERSOLL R, ELLIOTT H, AMES BN: N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro. FASEB J. (2001) 15:2196-2204.
-
(2001)
FASEB J
, vol.15
, pp. 2196-2204
-
-
Atamna, H.1
Robinson, C.2
Ingersoll, R.3
Elliott, H.4
Ames, B.N.5
-
43
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
GLENNER GG, WONG CW. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem. Biophys. Res. Commun. (1984) 120:885-890.
-
(1984)
Biochem. Biophys. Res. Commun
, vol.120
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
44
-
-
0012510759
-
Amyloid plaque core protein in Alzheimer's disease and Down's syndrome
-
MASTERS CL, SIMMS G, WEINMAN NA, MULTHAUP G, MCDONALD BL, BEYREUTHER K: Amyloid plaque core protein in Alzheimer's disease and Down's syndrome. Proc. Natl. Acad. Sci. USA (1985) 82:4245-4249.
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 4245-4249
-
-
Masters, C.L.1
Simms, G.2
Weinman, N.A.3
Multhaup, G.4
Mcdonald, B.L.5
Beyreuther, K.6
-
45
-
-
0009364134
-
Microtubule-associated protein tau is a major antigenic component of paired helical filaments in Alzheimer's disease
-
KOSIK KS, JOACHIM CL, SELKOE DJ: Microtubule-associated protein tau is a major antigenic component of paired helical filaments in Alzheimer's disease. Proc. Natl. Acad. Sci. USA (1986) 83:4044-4048.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4044-4048
-
-
Kosik, K.S.1
Joachim, C.L.2
Selkoe, D.J.3
-
46
-
-
0034568802
-
Intramembrane proteolysis by presenilins
-
STEINER H, HAASS C: Intramembrane proteolysis by presenilins. Nat. Rev. Mol. Cell Biol. (2000) 1:217-224.
-
(2000)
Nat. Rev. Mol. Cell Biol
, vol.1
, pp. 217-224
-
-
Steiner, H.1
Haass, C.2
-
47
-
-
0032545939
-
Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease
-
MAYEUX R, SAUNDERS AM, SHEA S et al.: Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer's disease. N. Engl. J. Med. (1998) 338:506-511.
-
(1998)
N. Engl. J. Med
, vol.338
, pp. 506-511
-
-
Mayeux, R.1
Saunders, A.M.2
Shea, S.3
-
48
-
-
0032890439
-
Alzheimer's disease and oxidative stress: Implications for novel therapeutic approaches
-
BEHL C: Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches. Prog. Neurobiol. (1999) 57:301-323.
-
(1999)
Prog. Neurobiol
, vol.57
, pp. 301-323
-
-
Behl, C.1
-
49
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
SELKOE DJ: Translating cell biology into therapeutic advances in Alzheimer's disease. Nature (1999) 399(Suppl.):A23-A31.
-
(1999)
Nature
, vol.399
, Issue.SUPPL.
-
-
Selkoe, D.J.1
-
50
-
-
0033961113
-
Multiple antioxidants in the prevention and treatment of Alzheimer's disease: Analysis of biologic rationale
-
PRASAD KN, HOVLAND AR, COLE WC et al.: Multiple antioxidants in the prevention and treatment of Alzheimer's disease: analysis of biologic rationale. Clin. Neuropharmacol. (2000) 23:2-13.
-
(2000)
Clin. Neuropharmacol
, vol.23
, pp. 2-13
-
-
Prasad, K.N.1
Hovland, A.R.2
Cole, W.C.3
-
51
-
-
0033954991
-
Oxidative stress and Alzheimer's disease
-
CHRISTEN Y: Oxidative stress and Alzheimer's disease. Am. J. Clin. Nutr. (2000) 71(Suppl.):621S-629S.
-
(2000)
Am. J. Clin. Nutr
, vol.71
, Issue.SUPPL.
-
-
Christen, Y.1
-
52
-
-
0034923434
-
Cytosolic peroxidative damage is an early event in Alzheimer's disease
-
NUNOMURA A, PERRY G, ALIEV G et al.: Cytosolic peroxidative damage is an early event in Alzheimer's disease. J. Neuropathol. Exp. Neurol. (2001) 60:759-767.
-
(2001)
J. Neuropathol. Exp. Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
-
53
-
-
0033045848
-
In vitro peroxidase oxidation induces stable dimers of β-amyloid (1-42) through dityrosine bridge formation
-
GALEAZZI L, RONCHI P, FRANCESCHI C, GIUNTA S: In vitro peroxidase oxidation induces stable dimers of β-amyloid (1-42) through dityrosine bridge formation. Amyloid (1999) 6:7-13.
-
(1999)
Amyloid
, vol.6
, pp. 7-13
-
-
Galeazzi, L.1
Ronchi, P.2
Franceschi, C.3
Giunta, S.4
-
54
-
-
0034663858
-
Accelerated accumulation of amyloid β proteins on oxidatively damaged lipid membranes
-
KOPPAKA V, AXELSEN PH: Accelerated accumulation of amyloid β proteins on oxidatively damaged lipid membranes. Biochemistry (2000) 39:10011-10016.
-
(2000)
Biochemistry
, vol.39
, pp. 10011-10016
-
-
Koppaka, V.1
Axelsen, P.H.2
-
55
-
-
0035849879
-
Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats
-
PERUTZ MF, WINDLE AH: Cause of neural death in neurodegenerative diseases attributable to expansion of glutamine repeats. Nature (2001) 412:143-144.
-
(2001)
Nature
, vol.412
, pp. 143-144
-
-
Perutz, M.F.1
Windle, A.H.2
-
56
-
-
0028985574
-
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
-
GAMES D, ADAMS D, ALESSANDRI R et al.: Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein. Nature (1995) 373:523-527.
-
(1995)
Nature
, vol.373
, pp. 523-527
-
-
Games, D.1
Adams, D.2
Alessandri, R.3
-
57
-
-
0011444914
-
Two amyloid precursor protein transgenic mouse models with Alzheimer's disease-like pathology
-
STURCHLER-PIERRAT C, ABRAMOWSKI D, DUKE M et al.: Two amyloid precursor protein transgenic mouse models with Alzheimer's disease-like pathology. Proc. Natl. Acad. Sci. USA (1997) 94:13287-13292.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 13287-13292
-
-
Sturchler-Pierrat, C.1
Abramowski, D.2
Duke, M.3
-
58
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
HOLCOMB L, GORDON MN, MCGOWAN E et al.: Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat. Med. (1998) 4:97-100.
-
(1998)
Nat. Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
Mcgowan, E.3
-
59
-
-
0033784099
-
Modeling Alzheimer's disease in transgenic mice: Effect of age and of presenilin 1 on amyloid biochemistry and pathology in APP/London mice
-
DEWACHTER I, VAN DORPE J, SPITTAELS K et al.: Modeling Alzheimer's disease in transgenic mice: effect of age and of presenilin 1 on amyloid biochemistry and pathology in APP/London mice. Exp. Gerontol. (2000) 35:831-841.
-
(2000)
Exp. Gerontol
, vol.35
, pp. 831-841
-
-
Dewachter, I.1
Van Dorpe, J.2
Spittaels, K.3
-
60
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
LEWIS J, DICKSON DW, LIN WL et al: Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science (2001) 293:1487-1491.
-
(2001)
Science
, vol.293
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.L.3
-
61
-
-
0033807836
-
An improved method of preparing the amyloid β-protein for fibrillogenesis and neurotoxicity experiments
-
FEZOUI Y, HARTLEY DM, HARPER JD et al.: An improved method of preparing the amyloid β-protein for fibrillogenesis and neurotoxicity experiments. Amyloid (2000) 7:166-178.
-
(2000)
Amyloid
, vol.7
, pp. 166-178
-
-
Fezoui, Y.1
Hartley, D.M.2
Harper, J.D.3
-
63
-
-
0030967165
-
A controlled trial of selegiline, α-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's disease cooperative study
-
SANO M, ERNESTO C, THOMAS RG et al.: A controlled trial of selegiline, α-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's disease cooperative study. N. Engl. J. Med. (1997) 336:1216-1222.
-
(1997)
N. Engl. J. Med
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
-
64
-
-
0033958696
-
Vitamin E and Alzheimer's disease: The basis for additional clinical trials
-
GRUNDMAN M: Vitamin E and Alzheimer's disease: the basis for additional clinical trials. Am. J. Clin. Nutr. (2000) 71 (Suppl.):630S-636S.
-
(2000)
Am. J. Clin. Nutr
, vol.71
, Issue.SUPPL.
-
-
Grundman, M.1
-
65
-
-
0032999243
-
Selegiline in the treatment of Alzheimer's disease: A long-term randomized placebo-controlled trial
-
Czech and Slovak Senile Dementia of Alzheimer Type Study Group
-
FILIP V, KOLIBAS E: Selegiline in the treatment of Alzheimer's disease: a long-term randomized placebo-controlled trial. Czech and Slovak Senile Dementia of Alzheimer Type Study Group. J. Psychiatry Neurosci. (1999) 24:234-243.
-
(1999)
J. Psychiatry Neurosci
, vol.24
, pp. 234-243
-
-
Filip, V.1
Kolibas, E.2
-
66
-
-
0031943163
-
L-Deprenyl in Alzheimer's disease: Cognitive and behavioral effects
-
FREEDMAN M, REWILAK D, XERRI T et al.: L-Deprenyl in Alzheimer's disease: cognitive and behavioral effects. Neurology (1998) 50:660-668.
-
(1998)
Neurology
, vol.50
, pp. 660-668
-
-
Freedman, M.1
Rewilak, D.2
Xerri, T.3
-
67
-
-
0034090510
-
Selegiline treatment and the extent of degenerative changes in brain tissue of patients with Alzheimer's disease
-
ALAFUZOFF I, HELISALMI S, HEINONEN EH et al.: Selegiline treatment and the extent of degenerative changes in brain tissue of patients with Alzheimer's disease. Eur. J. Clin. Pharmacol. (2000) 55:815-819.
-
(2000)
Eur. J. Clin. Pharmacol
, vol.55
, pp. 815-819
-
-
Alafuzoff, I.1
Helisalmi, S.2
Heinonen, E.H.3
-
68
-
-
0034718466
-
A 1-year controlled trial of acetyl-L-carnitine in early-onset AD
-
THAL LJ, CALVANI M, AMATO A, CARTA A et al.: A 1-year controlled trial of acetyl-L-carnitine in early-onset AD. Neurology (2000) 55:805-810.
-
(2000)
Neurology
, vol.55
, pp. 805-810
-
-
Thal, L.J.1
Calvani, M.2
Amato, A.3
Carta, A.4
-
69
-
-
9544240348
-
A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease
-
THAL LJ, CARTA A, CLARKE WR et al.: A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology (1996) 47:705-711.
-
(1996)
Neurology
, vol.47
, pp. 705-711
-
-
Thal, L.J.1
Carta, A.2
Clarke, W.R.3
-
70
-
-
0026002366
-
Long-term acetyl-L-carnitine treatment in Alzheimer's disease
-
SPAGNOLI A, LUCCA U, MENASCE G et al. Long-term acetyl-L-carnitine treatment in Alzheimer's disease. Neurology (1991) 41:1726-1732.
-
(1991)
Neurology
, vol.41
, pp. 1726-1732
-
-
Spagnoli, A.1
Lucca, U.2
Menasce, G.3
-
71
-
-
0033653231
-
Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: Relevance for its mode of action in Alzheimer's disease and geriatric depression
-
PETTEGREW JW, LEVINE J, MCCLURE RJ: Acetyl-L-carnitine physical-chemical, metabolic, and therapeutic properties: relevance for its mode of action in Alzheimer's disease and geriatric depression. Mol. Psychiatry (2000) 5:616-632.
-
(2000)
Mol. Psychiatry
, vol.5
, pp. 616-632
-
-
Pettegrew, J.W.1
Levine, J.2
Mcclure, R.J.3
-
72
-
-
0034937436
-
The action of aceryl-L-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones
-
VIRMANI MA, CASO V, SPADONI A, ROSSI S, RUSSO F, GAETANI F: The action of aceryl-L-carnitine on the neurotoxicity evoked by amyloid fragments and peroxide on primary rat cortical neurones. Ann. NY Acad. Sci. (2001) 939:162-178.
-
(2001)
Ann. NY Acad. Sci
, vol.939
, pp. 162-178
-
-
Virmani, M.A.1
Caso, V.2
Spadoni, A.3
Rossi, S.4
Russo, F.5
Gaetani, F.6
-
73
-
-
0031593616
-
Sustained efficacy and safety of idebenone in the treatment of Alzheimer's disease: Update on a 2-year double-blind multicentre study
-
GUTZMANN H, HADLER D: Sustained efficacy and safety of idebenone in the treatment of Alzheimer's disease: update on a 2-year double-blind multicentre study. J. Neural Transm. Suppl. (1998) 54:301-310.
-
(1998)
J. Neural Transm. Suppl
, vol.54
, pp. 301-310
-
-
Gutzmann, H.1
Hadler, D.2
-
74
-
-
0030758077
-
A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease
-
WEYER G, BABEJ-DOLLE RM, HADLER D, HOFMANN S, HERRMANN WM: A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease. Neuropsychobiology (1997) 36:73-82.
-
(1997)
Neuropsychobiology
, vol.36
, pp. 73-82
-
-
Weyer, G.1
Babej-dolle, R.M.2
Hadler, D.3
Hofmann, S.4
Herrmann, W.M.5
-
75
-
-
0032898672
-
Protective effects of idebenone and α-tocopherol on β-amyloid-(1-42)-induced learning and memory deficits in fats: Implication of oxidative stress in β-amyloid-induced neurotoxicity in vivo
-
YAMADA K, TANAKA T, HAN D, SENZAKI K, KAMEYAMA T, NABESHIMA T: Protective effects of idebenone and α-tocopherol on β-amyloid-(1-42)-induced learning and memory deficits in fats: implication of oxidative stress in β-amyloid-induced neurotoxicity in vivo. Eur. J. Neurosci. (1999) 11:83-90.
-
(1999)
Eur. J. Neurosci
, vol.11
, pp. 83-90
-
-
Yamada, K.1
Tanaka, T.2
Han, D.3
Senzaki, K.4
Kameyama, T.5
Nabeshima, T.6
-
76
-
-
0031741705
-
Idebenone protects hippocampal neurons against amyloid β-peptide-induced neurotoxicity in rat primary cultures
-
HIRAI K, HAYAKO H, KATO K, MIYAMOTO M: Idebenone protects hippocampal neurons against amyloid β-peptide-induced neurotoxicity in rat primary cultures. Naunyn Schmiedebergs Arch. Pharmacol. (1998) 358:582-585.
-
(1998)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.358
, pp. 582-585
-
-
Hirai, K.1
Hayako, H.2
Kato, K.3
Miyamoto, M.4
-
77
-
-
0035940625
-
Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease
-
ADAIR JC, KNOEFEL JE, MORGAN N: Controlled trial of N-acetylcysteine for patients with probable Alzheimer's disease. Neurology (2001) 57:1515-1517.
-
(2001)
Neurology
, vol.57
, pp. 1515-1517
-
-
Adair, J.C.1
Knoefel, J.E.2
Morgan, N.3
-
78
-
-
0029844969
-
Estrogen replacement therapy and risk of Alzheimer's disease
-
PAGANINI-HILL A, HENDERSON VW. Estrogen replacement therapy and risk of Alzheimer's disease. Arch. Intern. Med. (1996) 156:2213-2217.
-
(1996)
Arch. Intern. Med
, vol.156
, pp. 2213-2217
-
-
Paganini-hill, A.1
Henderson, V.W.2
-
79
-
-
0030591669
-
Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
-
TANG MX, JACOBS D, STERN Y et al.: Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet (1996) 348:429-432.
-
(1996)
Lancet
, vol.348
, pp. 429-432
-
-
Tang, M.X.1
Jacobs, D.2
Stern, Y.3
-
80
-
-
0033596811
-
Postmenopausal estrogen replacement therapy and risk of AD: A population-based study
-
WARING SC, ROCCA WA, PETERSEN RC et al.: Postmenopausal estrogen replacement therapy and risk of AD: a population-based study. Neurology (1999) 52:965-970.
-
(1999)
Neurology
, vol.52
, pp. 965-970
-
-
Waring, S.C.1
Rocca, W.A.2
Petersen, R.C.3
-
81
-
-
0035956580
-
Hormone replacement therapy and reduced cognitive decline in older women: The Cache County Study
-
CARLSON MC, ZANDI PP, PLASSMAN BL et al.: Hormone replacement therapy and reduced cognitive decline in older women: The Cache County Study. Neurology (2001) 57:2210-2216.
-
(2001)
Neurology
, vol.57
, pp. 2210-2216
-
-
Carlson, M.C.1
Zandi, P.P.2
Plassman, B.L.3
-
82
-
-
0035936004
-
Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease
-
IN 'T VELD BA, RUITENBERG A, HOFMAN A et al.: Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease. N. Engl. J. Med. (2001) 345:1515-1521.
-
(2001)
N. Engl. J. Med
, vol.345
, pp. 1515-1521
-
-
In't Veld, B.A.1
Ruitenberg, A.2
Hofman, A.3
-
83
-
-
0035936009
-
Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease?
-
BREITNER JC, ZANDI PP: Do nonsteroidal antiinflammatory drugs reduce the risk of Alzheimer's disease? N. Engl. Med. (2001) 345:1567-1568.
-
(2001)
N. Engl. Med
, vol.345
, pp. 1567-1568
-
-
Breitner, J.C.1
Zandi, P.P.2
-
84
-
-
0035696257
-
Do NSAIDs prevent Alzheimer's disease? And, if so, why? The epidemiological evidence
-
ZANDI PP, BREITNER JC: Do NSAIDs prevent Alzheimer's disease? And, if so, why? The epidemiological evidence. Neurobiol. Aging (2001) 22:811-817.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 811-817
-
-
Zandi, P.P.1
Breitner, J.C.2
-
86
-
-
0026551329
-
Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease
-
MCGEER PL, ROGERS J: Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease. Neurology (1992) 42:447-449.
-
(1992)
Neurology
, vol.42
, pp. 447-449
-
-
Mcgeer, P.L.1
Rogers, J.2
-
88
-
-
0033643625
-
The female sex hormone oestrogen as neuroprotectant: Activities at various levels
-
BEHL C, MOOSMANN B, MANTHEY D, HECK S: The female sex hormone oestrogen as neuroprotectant: activities at various levels. Novartis Found. Symp. (2000) 230:221-238.
-
(2000)
Novartis Found. Symp
, vol.230
, pp. 221-238
-
-
Behl, C.1
Moosmann, B.2
Manthey, D.3
Heck, S.4
-
89
-
-
0033304765
-
Estrogen actions in the central nervous system
-
MCEWEN BS, ALVES SE: Estrogen actions in the central nervous system. Endocr. Rev. (1999) 20:279-307.
-
(1999)
Endocr. Rev
, vol.20
, pp. 279-307
-
-
Mcewen, B.S.1
Alves, S.E.2
-
90
-
-
0034725724
-
Phagocytes and oxidative stress
-
BABIOR BM: Phagocytes and oxidative stress. Am. J. Med. (2000) 109:33-44.
-
(2000)
Am. J. Med
, vol.109
, pp. 33-44
-
-
Babior, B.M.1
-
91
-
-
0034012175
-
Cyclooxygenase-2 contributes to N-methyl-D-aspartate-mediated neuronal cell death in primary cortical cell culture
-
HEWETT SJ, ULIASZ TE, VIDWANS AS, HEWETT JA: Cyclooxygenase-2 contributes to N-methyl-D-aspartate-mediated neuronal cell death in primary cortical cell culture. J. Pharmacol. Exp. Ther. (2000) 293:417-425.
-
(2000)
J. Pharmacol. Exp. Ther
, vol.293
, pp. 417-425
-
-
Hewett, S.J.1
Uliasz, T.E.2
Vidwans, A.S.3
Hewett, J.A.4
-
92
-
-
0030867994
-
A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
-
LI Y, MAHER P, SCHUBERT D: A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion. Neuron (1997) 19:453-463.
-
(1997)
Neuron
, vol.19
, pp. 453-463
-
-
Li, Y.1
Maher, P.2
Schubert, D.3
-
93
-
-
0027874412
-
Antioxidant profile of nimesulide, indomethacin and diclofenac in phosphatidylcholine liposomes (PCL) as membrane model
-
MAFFEI FACINO R, CARINI M, ALDINI G, SAIBENE L, MACCIOCCHI A: Antioxidant profile of nimesulide, indomethacin and diclofenac in phosphatidylcholine liposomes (PCL) as membrane model. Int. J. Tissue React. (1993) 15:225-234.
-
(1993)
Int. J. Tissue React
, vol.15
, pp. 225-234
-
-
Maffei Facino, R.1
Carini, M.2
Aldini, G.3
Saibene, L.4
Macciocchi, A.5
-
94
-
-
0034446002
-
An investigation into the neuroprotective properties of ibuprofen
-
LAMBAT Z, CONRAD N, ANOOPKUMAR-DUKIE S, WALKER RB, DAYA S: An investigation into the neuroprotective properties of ibuprofen. Metab. Brain Dis. (2000) 15:249-256.
-
(2000)
Metab. Brain Dis
, vol.15
, pp. 249-256
-
-
Lambat, Z.1
Conrad, N.2
Anoopkumar-dukie, S.3
Walker, R.B.4
Daya, S.5
-
95
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
-
WEGGEN S, ERIKSEN JL, DAS P et al.: A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity. Nature (2001) 414:212-216.
-
(2001)
Nature
, vol.414
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
-
96
-
-
0033529941
-
The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties
-
MOOSMANN B, BEHL C: The antioxidant neuroprotective effects of estrogens and phenolic compounds are independent from their estrogenic properties. Proc. Natl. Acad Sci. USA (1999) 96:8867-8872.
-
(1999)
Proc. Natl. Acad Sci. USA
, vol.96
, pp. 8867-8872
-
-
Moosmann, B.1
Behl, C.2
-
97
-
-
0035917938
-
The effects of hormone replacement therapy on lipid peroxidation and antioxidant status
-
OZDEN S, DILDAR K, KADIR YH, GULIZAR K: The effects of hormone replacement therapy on lipid peroxidation and antioxidant status. Maturitas (2001) 38:165-170.
-
(2001)
Maturitas
, vol.38
, pp. 165-170
-
-
Ozden, S.1
Dildar, K.2
Kadir, Y.H.3
Gulizar, K.4
-
98
-
-
0034201317
-
Hormone replacement therapy for oxidative stress in postmenopausal women with hot flushes
-
LEAL M, DIAZ J, SERRANO E, ABELLAN J, CARBONELL LF: Hormone replacement therapy for oxidative stress in postmenopausal women with hot flushes. Obstet. Gynecol. (2000) 95:804-809.
-
(2000)
Obstet. Gynecol
, vol.95
, pp. 804-809
-
-
Leal, M.1
Diaz, J.2
Serrano, E.3
Abellan, J.4
Carbonell, L.F.5
-
99
-
-
0035201910
-
Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women
-
BHAVNANI BR, CECUTTI A, GERULATH A, WOOLEVER AC, BERCO M: Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women. Menopause (2001) 8:408-419.
-
(2001)
Menopause
, vol.8
, pp. 408-419
-
-
Bhavnani, B.R.1
Cecutti, A.2
Gerulath, A.3
Woolever, A.C.4
Berco, M.5
-
100
-
-
0032702248
-
Can estrogen keep you smart? Evidence from clinical studies
-
SHERWIN BB: Can estrogen keep you smart? Evidence from clinical studies. J. Psychiatry Neurosci. (1999) 24:315-321.
-
(1999)
J. Psychiatry Neurosci
, vol.24
, pp. 315-321
-
-
Sherwin, B.B.1
-
101
-
-
0034711656
-
Estrogen for Alzheimer's disease in women: Randomized, double blind, placebo-controlled trial
-
HENDERSON VW, PAGANINI-HILL A, MILLER BL et al: Estrogen for Alzheimer's disease in women: randomized, double blind, placebo-controlled trial. Neurology (2000) 54:295-301.
-
(2000)
Neurology
, vol.54
, pp. 295-301
-
-
Henderson, V.W.1
Paganini-Hill, A.2
Miller, B.L.3
-
102
-
-
0034643897
-
Effects of estrogen on cognition, mood, and cerebral blood flow in AD: A controlled study
-
WANG PN, LIAO SQ, LIU RS et al.: Effects of estrogen on cognition, mood, and cerebral blood flow in AD: a controlled study. Neurology (2000) 54:2061-2066.
-
(2000)
Neurology
, vol.54
, pp. 2061-2066
-
-
Wang, P.N.1
Liao, S.Q.2
Liu, R.S.3
-
103
-
-
0034704547
-
Estrogen replacement therapy for treatment of mild to moderate Alzheimer's disease: A randomized controlled trial. Alzheimer's disease Cooperative Study
-
MULNARD RA, COTMAN CW, KAWAS C et al.: Estrogen replacement therapy for treatment of mild to moderate Alzheimer's disease: a randomized controlled trial. Alzheimer's disease Cooperative Study. JAMA (2000) 283:1007-1015.
-
(2000)
JAMA
, vol.283
, pp. 1007-1015
-
-
Mulnard, R.A.1
Cotman, C.W.2
Kawas, C.3
-
104
-
-
0035964288
-
High-dose estradiol improves cognition for women with AD: Results of a randomized study
-
ASTHANA S, BAKER LD, CRAFT S et al.: High-dose estradiol improves cognition for women with AD: results of a randomized study. Neurology (2001) 57:605-612.
-
(2001)
Neurology
, vol.57
, pp. 605-612
-
-
Asthana, S.1
Baker, L.D.2
Craft, S.3
-
105
-
-
0033650691
-
Oestrogen and cognitive function throughout the female lifespan
-
SHERWIN BB: Oestrogen and cognitive function throughout the female lifespan. Novartis Found. Symp. (2000) 230:188-201.
-
(2000)
Novartis Found. Symp
, vol.230
, pp. 188-201
-
-
Sherwin, B.B.1
-
106
-
-
0034620538
-
A randomized controlled trial of prednisone in Alzheimer's disease
-
Alzheimer's. disease Cooperative Study
-
AISEN PS, DAVIS KL, BERG JD et al.: A randomized controlled trial of prednisone in Alzheimer's disease. Alzheimer's disease Cooperative Study. Neurology (2000) 54:588-593.
-
(2000)
Neurology
, vol.54
, pp. 588-593
-
-
Aisen, P.S.1
Davis, K.L.2
Berg, J.D.3
-
107
-
-
0033551547
-
A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease
-
SCHARF S, MANDER A, UGONI A, VAJDA F, CHRISTOPHIDIS N: A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease. Neurology (1999) 53:197-201.
-
(1999)
Neurology
, vol.53
, pp. 197-201
-
-
Scharf, S.1
Mander, A.2
Ugoni, A.3
Vajda, F.4
Christophidis, N.5
-
108
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
ROGERS J, KIRBY LC, HEMPELMAN SR et al.: Clinical trial of indomethacin in Alzheimer's disease. Neurology (1993) 43:1609-1611.
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
-
109
-
-
0035845325
-
Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: An 18-month randomised, double-blind, placebo-controlled study
-
VAN GOOL WA, WEINSTEIN HC, SCHELTENS PK, WALSTRA GJ: Effect of hydroxychloroquine on progression of dementia in early Alzheimer's disease: an 18-month randomised, double-blind, placebo-controlled study. Lancet (2001) 358:455-460.
-
(2001)
Lancet
, vol.358
, pp. 455-460
-
-
Van Gool, W.A.1
Weinstein, H.C.2
Scheltens, P.K.3
Walstra, G.J.4
-
111
-
-
0034930671
-
Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system
-
REITER RJ, ACUNA-CASTROVIEJO D, TAN DX, BURKHARDT S: Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system. Ann. NY Acad. Sci. (2001) 939:200-215.
-
(2001)
Ann. NY Acad. Sci
, vol.939
, pp. 200-215
-
-
Reiter, R.J.1
Acuna-Castroviejo, D.2
Tan, D.X.3
Burkhardt, S.4
-
112
-
-
0033968704
-
An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: Implications for Alzheimer's disease
-
PAPPOLLA MA, CHYAN YJ, POEGGELER B et al.: An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease. J. Neural Transm. (2000) 107:203-231.
-
(2000)
J. Neural Transm
, vol.107
, pp. 203-231
-
-
Pappolla, M.A.1
Chyan, Y.J.2
Poeggeler, B.3
-
113
-
-
0035846613
-
Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid β peptide
-
POEGGELER B, MIRAVALLE L, ZAGORSKI MG et al.: Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid β peptide. Biochemistry (2001) 40:14995-15001.
-
(2001)
Biochemistry
, vol.40
, pp. 14995-15001
-
-
Poeggeler, B.1
Miravalle, L.2
Zagorski, M.G.3
-
114
-
-
0035826874
-
Melatonin acts as antioxidant and pro oxidant in an organotypic slice culture model of Alzheimer's disease Neuroreport
-
CLAPP-LILLY KL, SMITH MA, PERRY G, HARRIS PL, ZHU X, DUFFY LK: Melatonin acts as antioxidant and pro oxidant in an organotypic slice culture model of Alzheimer's disease. Neuroreport (2001) 12:1277-1280.
-
(2001)
, vol.12
, pp. 1277-1280
-
-
Clapp-lilly, K.L.1
Smith, M.A.2
Perry, G.3
Harris, P.L.4
Zhu, X.5
Duffy, L.K.6
-
115
-
-
0033994649
-
Melatonin treatment stabilizes chronobiologic and cognitive symptoms in Alzheimer's disease
-
BRUSCO LI, MARQUEZ M, CARDINALI DP: Melatonin treatment stabilizes chronobiologic and cognitive symptoms in Alzheimer's disease. Neuroendocrinol. Lett. (2000) 21:39-42.
-
(2000)
Neuroendocrinol. Lett
, vol.21
, pp. 39-42
-
-
Brusco, L.I.1
Marquez, M.2
Cardinali, D.P.3
-
116
-
-
0034232147
-
Gingko biloba extract (EGb 761) and CNS functions: Basic studies and clinical applications
-
DEFEUDIS FV, DRIEU K: Gingko biloba extract (EGb 761) and CNS functions: basic studies and clinical applications. Curr. Drug Targets (2000) 1:25-58.
-
(2000)
Curr. Drug Targets
, vol.1
, pp. 25-58
-
-
Defeudis, F.V.1
Drieu, K.2
-
117
-
-
0034121829
-
The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β-amyloid Eur
-
BASTIANETTO S, RAMASSAMY C, DORE S, CHRISTEN Y, POIRIER J, QUIRION R. The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by β-amyloid. Eur. J. Neurosci. (2000) 12:1882-1890.
-
(2000)
J. Neurosci
, vol.12
-
-
Bastianetto, S.1
Ramassamy, C.2
Dore, S.3
Christen, Y.4
Poirier, J.5
Quirion, R.6
-
118
-
-
0034122940
-
The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide induced toxicity: Involvement of its flavonoid constituents and protein kinase C
-
BASTIANETTO S, ZHENG WH, QUIRION R: The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide induced toxicity: involvement of its flavonoid constituents and protein kinase C. J. Neurochem. (2000) 74:2268-2277.
-
(2000)
J. Neurochem
, vol.74
, pp. 268-2277
-
-
Bastianetto, S.1
Zheng, W.H.2
Quirion, R.3
-
119
-
-
0035811001
-
The in vivo neuromodulatory effects of the herbal medicine Ginkgo biloba
-
WATANABE CM, WOLFFRAM S, ADER P et al: The in vivo neuromodulatory effects of the herbal medicine Ginkgo biloba. Proc. Natl. Acad Sci. USA (2001) 98:6577-6580.
-
(2001)
Proc. Natl. Acad Sci. USA
, vol.98
, pp. 6577-6580
-
-
Watanabe, C.M.1
Wolffram, S.2
Ader, P.3
-
120
-
-
0031788259
-
The efficacy of Ginkgo biloba on cognitive function in Alzheimer's disease
-
OKEN BS, STORZBACH DM, KAYE JA: The efficacy of Ginkgo biloba on cognitive function in Alzheimer's disease. Arch. Neurol. (1998) 55:1409-1415.
-
(1998)
Arch. Neurol
, vol.55
, pp. 1409-1415
-
-
Oken, B.S.1
Storzbach, D.M.2
Kaye, J.A.3
-
121
-
-
0029871249
-
Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia
-
KANOWSKI S, HERRMANN WM, STEPHAN K, WIERICH W, HORR R. Proof of efficacy of the Ginkgo biloba special extract EGb 761 in outpatients suffering from mild to moderate primary degenerative dementia of the Alzheimer type or multi-infarct dementia. Pharmacopsychiatry (1996) 29:47-56.
-
(1996)
Pharmacopsychiatry
, vol.29
, pp. 47-56
-
-
Kanowski, S.1
Herrmann, W.M.2
Stephan, K.3
Wierich, W.4
Horr, R.5
-
122
-
-
0030759072
-
A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia
-
North American EGb Study Group
-
LE BARS PL, KATZ MM, BERMAN N, ITIL TM, FREEDMAN AM, SCHATZBERG AF: A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA (1997) 278:1327-1332.
-
(1997)
JAMA
, vol.278
, pp. 1327-1332
-
-
Le Bars, P.L.1
Katz, M.M.2
Berman, N.3
Itil, T.M.4
Freedman, A.M.5
Schatzberg, A.F.6
-
123
-
-
0033785945
-
The efficacy of Ginkgo for elderly people with dementia and age associated memory impairment: New results of a randomized clinical trial
-
VAN DONGEN MC, VAN ROSSUM E, KESSELS AG, SIELHORST HJ, KNIPSCHILD PG: The efficacy of Ginkgo for elderly people with dementia and age associated memory impairment: new results of a randomized clinical trial. J. Am. Geriatr. Soc. (2000) 48:1183-1194.
-
(2000)
J. Am. Geriatr. Soc
, vol.48
, pp. 1183-1194
-
-
Van Dongen, M.C.1
Van Rossum, E.2
Kessels, A.G.3
Sielhorst, H.J.4
Knipschild, P.G.5
-
124
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
LIM GP, CHU T, YANG F, BEECH W, FRAUTSCHY SA, COLE GM: The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J. Neurosci. (2001) 21:8370-8377.
-
(2001)
J. Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
125
-
-
0035686083
-
Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology
-
FRAUTSCHY SA, HU W, KIM P et al.: Phenolic anti-inflammatory antioxidant reversal of Aβ-induced cognitive deficits and neuropathology. Neurobiol. Aging (2001) 22:993-1005.
-
(2001)
Neurobiol. Aging
, vol.22
, pp. 993-1005
-
-
Frautschy, S.A.1
Hu, W.2
Kim, P.3
-
126
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
-
CHERNY RA, ATWOOD CS, XILINAS ME et al.: Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice. Neuron (2001) 30:665-676.
-
(2001)
Neuron
, vol.30
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
-
127
-
-
0034968120
-
Metal chelator decreases Alzheimer β-amyloid plaques
-
GOURAS GK, BEAL MF: Metal chelator decreases Alzheimer β-amyloid plaques. Neuron (2001) 30:641-642.
-
(2001)
Neuron
, vol.30
, pp. 641-642
-
-
Gouras, G.K.1
Beal, M.F.2
-
128
-
-
0030885482
-
Iron accumulation in Alzheimer's disease is a source of redox-generated free radicals
-
SMITH MA, HARRIS PL, SAYRE LM, PERRY G: Iron accumulation in Alzheimer's disease is a source of redox-generated free radicals. Proc. Natl. Acad. Sci. USA (1997) 94:9866-9868.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 9866-9868
-
-
Smith, M.A.1
Harris, P.L.2
Sayre, L.M.3
Perry, G.4
-
129
-
-
0033601338
-
Cu(II) potentiation of Alzheimer Aβ neurotoxicity
-
HUANG X, CUAJUNGCO MP, ATWOOD CS et al.: Cu(II) potentiation of Alzheimer Aβ neurotoxicity. J. Biol. Chem. (1999) 274:37111-37116.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 37111-37116
-
-
Huang, X.1
Cuajungco, M.P.2
Atwood, C.S.3
-
130
-
-
0025726462
-
Intramuscular desferrioxamine in patients with Alzheimer's disease
-
CRAPPERMCLACHLAN DR, DALTON AJ, KRUCK TP et al.: Intramuscular desferrioxamine in patients with Alzheimer's disease. Lancet (1991) 337:1304-1308.
-
(1991)
Lancet
, vol.337
, pp. 1304-1308
-
-
Crappermclachlan, D.R.1
Dalton, A.J.2
Kruck, T.P.3
-
131
-
-
0028595618
-
The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation
-
MUNCH G, TANELI Y, SCHRAVEN E et al.: The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advanced glycosylation. J. Neural Transm. Park. Dis. Dement. Sect. (1994) 8:193-208.
-
(1994)
J. Neural Transm. Park. Dis. Dement. Sect
, vol.8
, pp. 193-208
-
-
Munch, G.1
Taneli, Y.2
Schraven, E.3
-
132
-
-
0030936591
-
Inhibitory effects of tenilsetam on the Maillard reaction
-
SHODA H, MIYATA S, LIU BF et al.: Inhibitory effects of tenilsetam on the Maillard reaction. Endocrinology (1997) 138:1886-1892.
-
(1997)
Endocrinology
, vol.138
, pp. 1886-1892
-
-
Shoda, H.1
Miyata, S.2
Liu, B.F.3
-
133
-
-
0028233494
-
Hydrogen peroxide mediates amyloid β protein toxicity
-
BEHL C, DAVIES JB, LESLEY R, SCHUBERT D: Hydrogen peroxide mediates amyloid β protein toxicity. Cell (1994) 77:817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davies, J.B.2
Lesley, R.3
Schubert, D.4
-
134
-
-
0029866991
-
β-Amyloid toxicity in organotypic hippocampal cultures: Protection by EUK 8, a synthetic catalytic free radical scavenger
-
BRUCE AJ, MALFROY B, BAUDRY M: β-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK 8, a synthetic catalytic free radical scavenger. Proc. Natl. Acad. Sci. USA (1996) 93:2312-2316.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2312-2316
-
-
Bruce, A.J.1
Malfroy, B.2
Baudry, M.3
-
135
-
-
0031911994
-
Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury
-
BAKER K, MARCUS CB, HUFFMAN K, KRUK H, MALFROY B, DOCTROW SR: Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. J. Pharmacol. Exp. Ther. (1998) 284:215-221.
-
(1998)
J. Pharmacol. Exp. Ther
, vol.284
, pp. 215-221
-
-
Baker, K.1
Marcus, C.B.2
Huffman, K.3
Kruk, H.4
Malfroy, B.5
Doctrow, S.R.6
-
136
-
-
0031562673
-
Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites
-
MALFROY B, DOCTROW SR, ORR PL, TOCCO G, FEDOSEYEVA EV, BENICHOU G: Prevention and suppression of autoimmune encephalomyelitis by EUK-8, a synthetic catalytic scavenger of oxygen-reactive metabolites. Cell. Immunol. (1997) 177:62-68.
-
(1997)
Cell Immunol
, vol.177
, pp. 62-68
-
-
Malfroy, B.1
Doctrow, S.R.2
Orr, P.L.3
Tocco, G.4
Fedoseyeva, E.V.5
Benichou, G.6
-
137
-
-
0035101472
-
Antioxidant therapy: A new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury
-
CUZZOCREA S, RILEY DP, CAPUTI AP, SALVEMINI D: Antioxidant therapy: a new pharmacological approach in shock, inflammation, and ischemia/reperfusion injury. Pharmacol. Rev. (2001) 53:135-159.
-
(2001)
Pharmacol. Rev
, vol.53
, pp. 135-159
-
-
Cuzzocrea, S.1
Riley, D.P.2
Caputi, A.P.3
Salvemini, D.4
-
138
-
-
0033578309
-
EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology
-
RONG Y, DOCTROW SR, TOCCO G, BAUDRY M: EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology. Proc. Natl. Acad. Sci. USA (1999) 96:9897-9902.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 9897-9902
-
-
Rong, Y.1
Doctrow, S.R.2
Tocco, G.3
Baudry, M.4
-
141
-
-
0035979233
-
α-Synuclein occurs in lipid rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins
-
SHARON R, GOLDBERG MS, BARJOSEF I, BETENSKY RA, SHEN J, SELKOE DJ: α-Synuclein occurs in lipid rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins. Proc. Natl. Acad. Sci. USA (2001) 98:9110-9115.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9110-9115
-
-
Sharon, R.1
Goldberg, M.S.2
Barjosef, I.3
Betensky, R.A.4
Shen, J.5
Selkoe, D.J.6
-
142
-
-
0034077041
-
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
-
ABELIOVICH A, SCHMITZ Y, FARINAS I et al: Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron (2000) 25:239-252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
-
143
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
MASLIAH E ROCKENSTEIN E, VEINBERGS I et al.: Dopaminergic loss and inclusion body formation in α-synuclein mice: implications for neurodegenerative disorders. Science (2000) 287:1265-1269.
-
(2000)
Science
, vol.287
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
-
144
-
-
0034663176
-
Neuropathology in mice expressing human α-synuclein
-
VAN DER PUTTEN H, WIEDERHOLD KH, PROBST A et al.: Neuropathology in mice expressing human α-synuclein. J. Neurosci. (2000) 20:6021-6029.
-
(2000)
J. Neurosci
, vol.20
, pp. 6021-6029
-
-
Van Der Putten, H.1
Wiederhold, K.H.2
Probst, A.3
-
145
-
-
0034326816
-
Expression of mutant α-synuclein causes increased susceptibility to dopamine toxicity
-
TABRIZI SJ, ORTH M, WILKINSON JM et al: Expression of mutant α-synuclein causes increased susceptibility to dopamine toxicity. Hum. Mol. Genet. (2000) 9:2683-2689.
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 2683-2689
-
-
Tabrizi, S.J.1
Orth, M.2
Wilkinson, J.M.3
-
146
-
-
0034674652
-
Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies
-
SOUZA JM, GIASSON BI, CHEN Q, LEE VM, ISCHIROPOULOS H: Dityrosine cross-linking promotes formation of stable α-synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies. J. Biol. Chem. (2000) 275:18344-18349.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 18344-18349
-
-
Souza, J.M.1
Giasson, B.I.2
Chen, Q.3
Lee, V.M.4
Ischiropoulos, H.5
-
147
-
-
0035834360
-
Kinetic stabilization of the α-synuclein protofibril by a dopamine-α-synuclein adduct
-
CONWAY KA, ROCHET JC, BIEGANSKI RM, LANSBURY PT: Kinetic stabilization of the α-synuclein protofibril by a dopamine-α-synuclein adduct. Science (2001) 294:1346-1349.
-
(2001)
Science
, vol.294
, pp. 1346-1349
-
-
Conway, K.A.1
Rochet, J.C.2
Bieganski, R.M.3
Lansbury, P.T.4
-
148
-
-
0035860983
-
Complete genomic screen in Parkinson's disease: Evidence for multiple genes
-
SCOTT WK, NANCE MA, WATTS RL et al.: Complete genomic screen in Parkinson's disease: evidence for multiple genes. JAMA (2001) 286:2239-2244.
-
(2001)
JAMA
, vol.286
, pp. 2239-2244
-
-
Scott, W.K.1
Nance, M.A.2
Watts, R.L.3
-
149
-
-
0034649710
-
Familial aggregation of Parkinson's disease in Iceland
-
SVEINBJORNSDOTTIR S, HICKS AA, JONSSON T et al.: Familial aggregation of Parkinson's disease in Iceland. N. Engl. J. Med. (2000) 343:1765-1770.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 1765-1770
-
-
Sveinbjornsdottir, S.1
Hicks, A.A.2
Jonsson, T.3
-
150
-
-
0033608187
-
Parkinson's disease in twins: An etiologic study
-
TANNER CM, OTTMAN R, GOLDMAN SM et al: Parkinson's disease in twins: an etiologic study. JAMA (1999) 281:341-346.
-
(1999)
JAMA
, vol.281
, pp. 341-346
-
-
Tanner, C.M.1
Ottman, R.2
Goldman, S.M.3
-
151
-
-
0035021395
-
Risk factors for Parkinson's disease: The leisure world cohort study
-
PAGANINI-HILL A: Risk factors for Parkinson's disease: the leisure world cohort study. Neuroepidemiology (2001) 20:118-124.
-
(2001)
Neuroepidemiology
, vol.20
, pp. 118-124
-
-
Paganini-Hill, A.1
-
152
-
-
0034950069
-
Prospective study of caffeine consumption and risk of Parkinson's disease in men and women
-
ASCHERIO A, ZHANG SM, HERNAN MA et al.: Prospective study of caffeine consumption and risk of Parkinson's disease in men and women. Ann. Neurol. (2001) 50:56-63.
-
(2001)
Ann. Neurol
, vol.50
, pp. 56-63
-
-
Ascherio, A.1
Zhang, S.M.2
Hernan, M.A.3
-
153
-
-
0035690443
-
Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson's disease
-
ROSS GW, PETROVITCH H: Current evidence for neuroprotective effects of nicotine and caffeine against Parkinson's disease. Drugs Aging (2001) 18:797-806.
-
(2001)
Drugs Aging
, vol.18
, pp. 797-806
-
-
Ross, G.W.1
Petrovitch, H.2
-
154
-
-
0033861939
-
Agricultural work and the risk of Parkinson's disease in Denmark, 1981-1993
-
TUCHSEN F. JENSEN AA: Agricultural work and the risk of Parkinson's disease in Denmark, 1981-1993. Scand. J. Work Environ. Health (2000) 26:359-362.
-
(2000)
Scand. J. Work Environ. Health
, vol.26
, pp. 359-362
-
-
Tuchsen, F.1
Jensen, A.A.2
-
156
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
POLYMEROPOULOS MH, LAVEDAN C, LEROY E et al.: Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science (1997) 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
157
-
-
0034798193
-
Genetics of Parkinson's disease
-
GASSER T: Genetics of Parkinson's disease. J. Neurol. (2001) 248:833-840.
-
(2001)
J. Neurol
, vol.248
, pp. 833-840
-
-
Gasser, T.1
-
158
-
-
0032942169
-
Management of Parkinson's disease. A review of current and new therapies
-
MENDIS T, SUCHOWERSKY O, LANG A. GAUTHIER S: Management of Parkinson's disease. A review of current and new therapies. Can. J. Neurol. Sci. (1999) 26:89-103.
-
(1999)
Can. J. Neurol. Sci
, vol.26
, pp. 89-103
-
-
Mendis, T.1
Suchowersky, O.2
Lang, A.3
Gauthier, S.4
-
159
-
-
0032890731
-
Parkinson's disease, the effect of levodopa, and the ELLDOPA trial
-
FAHN S: Parkinson's disease, the effect of levodopa, and the ELLDOPA trial. Arch. Neurol. (1999) 56:529-535.
-
(1999)
Arch. Neurol
, vol.56
, pp. 529-535
-
-
Fahn, S.1
-
160
-
-
0035035177
-
Neurosurgery for Parkinson's disease
-
ZESIEWICZ TA, HAUSER RA: Neurosurgery for Parkinson's disease. Semin. Neurol. (2001) 21:91-101.
-
(2001)
Semin. Neurol
, vol.21
, pp. 91-101
-
-
Zesiewicz, T.A.1
Hauser, R.A.2
-
161
-
-
0029845140
-
Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
-
GERLACH M, RIEDERER P: Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man. J. Neural Transm. (1996) 103:987-1041.
-
(1996)
J. Neural Transm
, vol.103
, pp. 987-1041
-
-
Gerlach, M.1
Riederer, P.2
-
162
-
-
0034993599
-
Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
-
BLUM B, TORCH S, LAMBENG N et al.: Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog. Neurobiol. (2001) 65:135-172.
-
(2001)
Prog. Neurobiol
, vol.65
, pp. 135-172
-
-
Blum, B.1
Torch, S.2
Lambeng, N.3
-
163
-
-
0035344211
-
Experimental models of Parkinson's disease
-
BEAL MF: Experimental models of Parkinson's disease. Nat. Rev. Neurosci. (2001) 2:325-334.
-
(2001)
Nat. Rev. Neurosci
, vol.2
, pp. 325-334
-
-
Beal, M.F.1
-
164
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidineanalog synthesis
-
LANGSTON JW, BALLARD P, TETRUD JW, IRWIN I: Chronic Parkinsonism in humans due to a product of meperidineanalog synthesis. Science (1983) 219:979-980.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
165
-
-
0033934847
-
The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: The role of mitochondrial complex I and reactive oxygen species revisited
-
NAKAMURA K, BINDOKAS VP, MARKS JD et al.: The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited. Mol. Pharmacol. (2000) 58:271-278.
-
(2000)
Mol. Pharmacol
, vol.58
, pp. 271-278
-
-
Nakamura, K.1
Bindokas, V.P.2
Marks, J.D.3
-
166
-
-
0014366602
-
Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine
-
THOENEN H, TRANZER JP: Chemical sympathectomy by selective destruction of adrenergic nerve endings with 6-hydroxydopamine. Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol. (1968) 261:271-288.
-
(1968)
Naunyn Schmiedebergs Arch. Exp. Pathol. Pharmakol
, vol.261
, pp. 271-288
-
-
Thoenen, H.1
Tranzer, J.P.2
-
167
-
-
0014665354
-
Lesions of central norepinephrine terminals with 6-OH-dopamine: Biochemistry and fine structure
-
BLOOM FE, ALGERI S, GROPPETTI A, REVUELTA A, COSTA E: Lesions of central norepinephrine terminals with 6-OH-dopamine: biochemistry and fine structure. Science (1969) 166:1284-1286.
-
(1969)
Science
, vol.166
, pp. 1284-1286
-
-
Bloom, F.E.1
Algeri, S.2
Groppetti, A.3
Revuelta, A.4
Costa, E.5
-
168
-
-
0027331917
-
The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls
-
ANDREW R, WATSON DC, BEST SA, MIDGLEY JM, WENLONG H, PETTY RK: The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls. Neurochem. Res. (1993) 18:1175-1177.
-
(1993)
Neurochem. Res
, vol.18
, pp. 1175-1177
-
-
Andrew, R.1
Watson, D.C.2
Best, S.A.3
Midgley, J.M.4
Wenlong, H.5
Petty, R.K.6
-
169
-
-
0032972263
-
Does levodopa accelerate Parkinson's disease?
-
SIMUNI T, STERN MB: Does levodopa accelerate Parkinson's disease? Drugs Aging (1999) 14:399-408.
-
(1999)
Drugs Aging
, vol.14
, pp. 399-408
-
-
Simuni, T.1
Stern, M.B.2
-
170
-
-
0030598917
-
Dopamine, 6-hydroxydopamine, iron, and dioxygen-their mutual interactions and possible implication in the development of Parkinson's disease
-
LINERT W, HERLINGER E, JAMESON RE KIENZL E, JELLINGER K, YOUDIM MB: Dopamine, 6-hydroxydopamine, iron, and dioxygen-their mutual interactions and possible implication in the development of Parkinson's disease. Biochim. Biophys. Acta. (1996) 1316:160-168.
-
(1996)
Biochim. Biophys. Acta
, vol.1316
, pp. 160-168
-
-
Linert, W.1
Herlinger, E.2
Jameson, R.E.3
Kienzl, E.4
Jellinger, K.5
Youdim, M.B.6
-
171
-
-
0032975570
-
The role of iron in neurodegeneration: Prospects for pharmacotherapy of Parkinson's disease
-
JELLINGER KA: The role of iron in neurodegeneration: prospects for pharmacotherapy of Parkinson's disease. Drugs Aging (1999) 14:115-140.
-
(1999)
Drugs Aging
, vol.14
, pp. 115-140
-
-
Jellinger, K.A.1
-
172
-
-
0032511134
-
Mechanism of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine and its prevention by desferrioxamine
-
GLINKA Y, TIPTON KF, YOUDIM MB: Mechanism of inhibition of mitochondrial respiratory complex I by 6-hydroxydopamine and its prevention by desferrioxamine. Eur. J. Pharmacol. (1998) 351:121-129.
-
(1998)
Eur. J. Pharmacol
, vol.351
, pp. 121-129
-
-
Glinka, Y.1
Tipton, K.F.2
Youdim, M.B.3
-
173
-
-
0034882387
-
Methamphetamine neurotoxicity: Necrotic and apoptotic mechanisms and relevance to human abuse and treatment
-
DAVIDSON C, GOW AJ, LEE TH, ELLINWOOD EH: Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment. Brain Res. Brain Res. Rev. (2001) 36:1-22.
-
(2001)
Brain Res. Brain Res. Rev
, vol.36
, pp. 1-22
-
-
Davidson, C.1
Gow, A.J.2
Lee, T.H.3
Ellinwood, E.H.4
-
174
-
-
0034790565
-
Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation
-
XIA XG, SCHMIDT N, TEISMANN P, FERGER B, SCHULZ JB: Dopamine mediates striatal malonate toxicity via dopamine transporter-dependent generation of reactive oxygen species and D2 but not D1 receptor activation. J. Neurochem. (2001) 79:63-70.
-
(2001)
J. Neurochem
, vol.79
, pp. 63-70
-
-
Xia, X.G.1
Schmidt, N.2
Teismann, P.3
Ferger, B.4
Schulz, J.B.5
-
175
-
-
0034123981
-
Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin
-
NAKAMURA K, WRIGHT DA, WIATR T et al.: Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin. J. Neurochem. (2000) 74:2305-2314.
-
(2000)
J. Neurochem
, vol.74
, pp. 2305-2314
-
-
Nakamura, K.1
Wright, D.A.2
Wiatr, T.3
-
176
-
-
0033857143
-
Tetrahydrobiopterin is released from and causes preferential death of catecholaminergic cells by oxidative stress
-
CHOI HJ, JANG YJ, KIM HJ, HWANG O: Tetrahydrobiopterin is released from and causes preferential death of catecholaminergic cells by oxidative stress. Mol. Pharmacol. (2000) 58:633-640.
-
(2000)
Mol. Pharmacol
, vol.58
, pp. 633-640
-
-
Choi, H.J.1
Jang, Y.J.2
Kim, H.J.3
Hwang, O.4
-
177
-
-
0034654022
-
Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide
-
KOTSONIS P, FROHLICH LG, SHUTENKO ZV, HOREJSI R, PFLEIDERER W, SCHMIDT HH: Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide. Biochem. J. (2000) 346:767-776.
-
(2000)
Biochem. J
, vol.346
, pp. 767-776
-
-
Kotsonis, P.1
Frohlich, L.G.2
Shutenko, Z.V.3
Horejsi, R.4
Pfleiderer, W.5
Schmidt, H.H.6
-
178
-
-
0342723791
-
Nitric oxide in the pathogenesis of vascular disease
-
LI H, FORSTERMANN U: Nitric oxide in the pathogenesis of vascular disease. J. Pathol. (2000) 190:244-254.
-
(2000)
J. Pathol
, vol.190
, pp. 244-254
-
-
Li, H.1
Forstermann, U.2
-
179
-
-
0031577442
-
Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase
-
WEVER RM, VAN DAMT, VAN RIJN HJ, DE GROOT F, RABELINK TJ: Tetrahydrobiopterin regulates superoxide and nitric oxide generation by recombinant endothelial nitric oxide synthase. Biochem. Biophys. Res. Commun. (1997) 237:340-344.
-
(1997)
Biochem. Biophys. Res. Commun
, vol.237
, pp. 340-344
-
-
Wever, R.M.1
Van Damt, A.2
Van Rijn, H.J.3
De Groot, F.4
Rabelink, T.J.5
-
180
-
-
0027530638
-
Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
-
PARKINSON STUDY GROUP
-
PARKINSON STUDY GROUP: Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N. Engl. J. Med. (1993) 328:176-183.
-
(1993)
N. Engl. J. Med
, vol.328
, pp. 176-183
-
-
-
181
-
-
0028025072
-
The effect of deprenyl and tocopherol on cognitive performance in early untreated Parkinson's disease
-
Parkinson Study Group
-
KIEBURTZ K, MCDERMOTT M, COMO P et al: The effect of deprenyl and tocopherol on cognitive performance in early untreated Parkinson's disease. Parkinson Study Group. Neurology (1994) 44:1756-1759.
-
(1994)
Neurology
, vol.44
, pp. 1756-1759
-
-
Kieburtz, K.1
Mcdermott, M.2
Como, P.3
-
182
-
-
0029927070
-
Effect of lazabemide on the progression of disability in early Parkinson's disease
-
PARKINSON STUDY GROUP
-
PARKINSON STUDY GROUP: Effect of lazabemide on the progression of disability in early Parkinson's disease. Ann. Neurol. (1996) 40:99-107.
-
(1996)
Ann. Neurol
, vol.40
, pp. 99-107
-
-
-
183
-
-
0024343466
-
The effect of deprenyl (selegiline) on the natural history of Parkinson's disease
-
TETRUD JW, LANGSTON JW: The effect of deprenyl (selegiline) on the natural history of Parkinson's disease. Science (1989) 245:519-522.
-
(1989)
Science
, vol.245
, pp. 519-522
-
-
Tetrud, J.W.1
Langston, J.W.2
-
184
-
-
0022365018
-
Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: A longterm study
-
BIRKMAYER W, KNOLL J, RIEDERER P, YOUDIM MB, HARSV, MARTON J: Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease: a longterm study. J. Neural Transm. (1985) 64:113-127.
-
(1985)
J. Neural Transm
, vol.64
, pp. 113-127
-
-
Birkmayer, W.1
Knoll, J.2
Riederer, P.3
Youdim, M.B.4
Harsv, A.5
Marton, J.6
-
185
-
-
0030042620
-
Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects not requiring levodopa
-
PARKINSON STUDY GROUP
-
PARKINSON STUDY GROUP: Impact of deprenyl and tocopherol treatment on Parkinson's disease in DATATOP subjects not requiring levodopa. Ann. Neurol. (1996) 39:29-36.
-
(1996)
Ann. Neurol
, vol.39
, pp. 29-36
-
-
-
186
-
-
0031893241
-
Mortality in DATATOP: A multicenter trial in early Parkinson's disease
-
PARKINSON STUDY GROUP
-
PARKINSON STUDY GROUP: Mortality in DATATOP: a multicenter trial in early Parkinson's disease. Ann. Neurol. (1998) 43:318-325.
-
(1998)
Ann. Neurol
, vol.43
, pp. 318-325
-
-
-
187
-
-
0032542955
-
Investigation by Parkinson's disease Research Group of United Kingdom into excess mortality seen with combined levodopa and selegiline treatment in patients with early, mild Parkinson's disease: Further results of randomised trial and confidential inquiry
-
BEN-SHLOMO Y, CHURCHYARD A, HEAD J et al.: Investigation by Parkinson's disease Research Group of United Kingdom into excess mortality seen with combined levodopa and selegiline treatment in patients with early, mild Parkinson's disease: further results of randomised trial and confidential inquiry. BMJ (1998) 316:1191-1196.
-
(1998)
BMJ
, vol.316
, pp. 1191-1196
-
-
Ben-Shlomo, Y.1
Churchyard, A.2
Head, J.3
-
188
-
-
0034719031
-
Selegiline and mortality in subjects with Parkinson's disease: A longitudinal community study
-
DONNAN PT, STEINKE DT, STUBBINGS C, DAVEY PG, MACDONALD TM: Selegiline and mortality in subjects with Parkinson's disease: a longitudinal community study. Neurology (2000) 55:1785-1789.
-
(2000)
Neurology
, vol.55
, pp. 1785-1789
-
-
Donnan, P.T.1
Steinke, D.T.2
Stubbings, C.3
Davey, P.G.4
Macdonald, T.M.5
-
189
-
-
0031711714
-
DATATOP: A decade of neuroprotective inquiry. Deprenyl and tocopherol antioxidative therapy of parkinsonism
-
Parkinson study group
-
SHOULSON I, DATATOP: a decade of neuroprotective inquiry. Parkinson study group. Deprenyl and tocopherol antioxidative therapy of parkinsonism. Ann. Neurol. (1998) 44(Suppl. 1):S160-S166.
-
(1998)
Ann. Neurol
, vol.44
, Issue.SUPPL. 1
-
-
Shoulson, I.1
-
190
-
-
0026636491
-
A pilot trial of high-dose α-tocopherol and ascorbate in early Parkinson's disease
-
FAHN S: A pilot trial of high-dose α-tocopherol and ascorbate in early Parkinson's disease. Ann. Neurol. (1992) 32(Suppl.):S128-132.
-
(1992)
Ann. Neurol
, vol.32
, Issue.SUPPL.
-
-
Fahn, S.1
-
191
-
-
0023638144
-
α-Tocopherol and β-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl 1,2,3,6-tetrahydropyridine
-
PERRY TL, YONG VW, HANSEN S et al.: α-Tocopherol and β-carotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl 1,2,3,6-tetrahydropyridine. J. Neurol. Sci. (1987) 81:321-331.
-
(1987)
J. Neurol. Sci
, vol.81
, pp. 321-331
-
-
Perry, T.L.1
Yong, V.W.2
Hansen, S.3
-
192
-
-
0025831475
-
Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: Preliminary observations
-
MIHATSCH W, RUSS H, GERLACH M, RIEDERER P, PRZUNTEK H: Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations. J. Neural Transm. Park. Dis. Dement. Sect. (1991) 3:73-78.
-
(1991)
J. Neural Transm. Park. Dis. Dement. Sect
, vol.3
, pp. 73-78
-
-
Mihatsch, W.1
Russ, H.2
Gerlach, M.3
Riederer, P.4
Przuntek, H.5
-
194
-
-
0028348546
-
Nigrostriatal function in vitamin E deficiency: Clinical, experimental, and positron emission tomographic studies
-
DEXTER DT, BROOKS DJ, HARDING AE et al.: Nigrostriatal function in vitamin E deficiency: clinical, experimental, and positron emission tomographic studies. Ann. Neurol. (1994) 35:298-303.
-
(1994)
Ann. Neurol
, vol.35
, pp. 298-303
-
-
Dexter, D.T.1
Brooks, D.J.2
Harding, A.E.3
-
195
-
-
0027941090
-
Nigral dopaminergic cell loss in vitamin E deficient rats
-
DEXTER DT NANAYAKKARA I, GOSS SAMPSON MA et al.: Nigral dopaminergic cell loss in vitamin E deficient rats. Neuroreport (1994) 5:1773-1776.
-
(1994)
Neuroreport
, vol.5
, pp. 1773-1776
-
-
Dexter, D.T.1
Nanayakkara, I.2
Goss-Sampson, M.A.3
-
196
-
-
0026794186
-
α-Tocopherol levels in brain are not altered in Parkinson's disease
-
DEXTER DT, WARD RJ, WELLS FR et al.: α-Tocopherol levels in brain are not altered in Parkinson's disease. Ann. Neurol. (1992) 32:591-593.
-
(1992)
Ann. Neurol
, vol.32
, pp. 591-593
-
-
Dexter, D.T.1
Ward, R.J.2
Wells, F.R.3
-
197
-
-
0031746550
-
α-Tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study
-
Parkinson study group
-
VATASSERY GT, FAHN S, KUSKOWSKI MA: α-Tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study. Parkinson study group. Neurology (1998) 50:1900-1902.
-
(1998)
Neurology
, vol.50
, pp. 1900-1902
-
-
Vatassery, G.T.1
Fahn, S.2
Kuskowski, M.A.3
-
198
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
SCHAPIRA AH, COOPER JM, DEXTER D, CLARK JB, JENNER P, MARSDEN CD: Mitochondrial complex I deficiency in Parkinson's disease. J. Neurochem. (1990) 54:823-827.
-
(1990)
J. Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
199
-
-
0025640845
-
Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease
-
SCHAPIRA AH, MANN VM, COOPER JM et al.: Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease. J. Neurochem. (1990) 55:2142-2145.
-
(1990)
J. Neurochem
, vol.55
, pp. 2142-2145
-
-
Schapira, A.H.1
Mann, V.M.2
Cooper, J.M.3
-
200
-
-
0026091344
-
Mitochondrial oxidative phosphorylation defects in Parkinson's disease
-
SHOFFNER JM, WATTS RL, JUNCOS JL, TORRONI A, WALLACE DC: Mitochondrial oxidative phosphorylation defects in Parkinson's disease. Ann. Neurol. (1991) 30:332-339.
-
(1991)
Ann. Neurol
, vol.30
, pp. 332-339
-
-
Shoffner, J.M.1
Watts, R.L.2
Juncos, J.L.3
Torroni, A.4
Wallace, D.C.5
-
201
-
-
0034620483
-
Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease
-
SIMON DK, MAYEUX R, MARDER K, KOWALL NW, BEAL ME JOHNS DR: Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology (2000) 54:703-709.
-
(2000)
Neurology
, vol.54
, pp. 703-709
-
-
Simon, D.K.1
Mayeux, R.2
Marder, K.3
Kowall, N.W.4
Beal, M.E.5
Johns, D.R.6
-
202
-
-
0034744308
-
Ubiquinone (coenzyme Q10) and mitochondria in oxidative stress of Parkinson's disease
-
EBADI M, GOVITRAPONG P, SHARMA S et al.: Ubiquinone (coenzyme Q10) and mitochondria in oxidative stress of Parkinson's disease. Biol. Signals Recept. (2001) 10:224-253.
-
(2001)
Biol. Signals Recept
, vol.10
, pp. 224-253
-
-
Ebadi, M.1
Govitrapong, P.2
Sharma, S.3
-
203
-
-
0035824814
-
A critical appraisal of the mitochondrial coenzyme Q pool
-
LENAZ G: A critical appraisal of the mitochondrial coenzyme Q pool. FEBS Lett. (2001) 509:151-155.
-
(2001)
FEBS Lett
, vol.509
, pp. 151-155
-
-
Lenaz, G.1
-
204
-
-
0033962637
-
Serum levels of coenzyme Q10 in patients with Parkinson's disease
-
JIMENEZ-JIMENEZ FJ, MOLINA JA, DE BUSTOS F et al.: Serum levels of coenzyme Q10 in patients with Parkinson's disease. J. Neural Transm. (2000) 107:177-181.
-
(2000)
J. Neural Transm
, vol.107
, pp. 177-181
-
-
Jimenez-Jimenez, F.J.1
Molina, J.A.2
De Bustos, F.3
-
205
-
-
0030612117
-
Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
-
SHULTS CW, HAAS RH, PASSOV D, BEAL MF: Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann. Neurol. (1997) 42:261-264.
-
(1997)
Ann. Neurol
, vol.42
, pp. 261-264
-
-
Shults, C.W.1
Haas, R.H.2
Passov, D.3
Beal, M.F.4
-
206
-
-
0033969735
-
Altered redox state of platelet coenzyme Q10 in Parkinson's disease
-
GOTZ ME, GERSTNER A, HARTH R et al.: Altered redox state of platelet coenzyme Q10 in Parkinson's disease. J. Neural Transm. (2000) 107:41-48.
-
(2000)
J. Neural Transm
, vol.107
, pp. 41-48
-
-
Gotz, M.E.1
Gerstner, A.2
Harth, R.3
-
207
-
-
0028978106
-
Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity
-
SCHULZ JB, HENSHAW DR, MATTHEWS RT, BEAL MF: Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity. Exp. Neurol. (1995) 132:279-283.
-
(1995)
Exp. Neurol
, vol.132
, pp. 279-283
-
-
Schulz, J.B.1
Henshaw, D.R.2
Matthews, R.T.3
Beal, M.F.4
-
208
-
-
0031105818
-
+ produces progressive neuronal degeneration which is mediated by oxidative stress
-
+ produces progressive neuronal degeneration which is mediated by oxidative stress. Exp. Neurol. (1997) 144:193-198.
-
(1997)
Exp. Neurol
, vol.144
, pp. 193-198
-
-
Fallon, J.1
Matthews, R.T.2
Hyman, B.T.3
Beal, M.F.4
-
209
-
-
0031594295
-
Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice
-
BEAL MF, MATTHEWS RT, TIELEMAN A, SHULTS CW: Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res. (1998) 783:109-114.
-
(1998)
Brain Res
, vol.783
, pp. 109-114
-
-
Beal, M.F.1
Matthews, R.T.2
Tieleman, A.3
Shults, C.W.4
-
210
-
-
0032555066
-
Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects
-
MATTHEWS RT, YANG L, BROWNE S, BALK M, BEAL MF: Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc. Natl. Acad. Sci. USA (1998) 95:8892-8897.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8892-8897
-
-
Matthews, R.T.1
Yang, L.2
Browne, S.3
Balk, M.4
Beal, M.F.5
-
211
-
-
0030626791
-
Q10 therapy in patients with idiopathic Parkinson's disease
-
STRIJKS E, KREMER HP, HORSTINK MW: Q10 therapy in patients with idiopathic Parkinson's disease. Mol. Aspects Med. (1997) 18(Suppl.):S237-240.
-
(1997)
Mol. Aspects Med
, vol.18
, Issue.SUPPL.
-
-
Strijks, E.1
Kremer, H.P.2
Horstink, M.W.3
-
212
-
-
0345451597
-
Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients
-
SHULTS CW, BEAL MF, FONTAINE D, NAKANO K, HAAS RH: Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients. Neurology (1998) 50:793-795.
-
(1998)
Neurology
, vol.50
, pp. 793-795
-
-
Shults, C.W.1
Beal, M.F.2
Fontaine, D.3
Nakano, K.4
Haas, R.H.5
-
213
-
-
0028826015
-
The frequency of idiopathic Parkinson's disease by age, ethnic group, and sex in northern Manhattan, 1988-1993
-
MAYEUX R, MARDER K, COTE LJ et al.: The frequency of idiopathic Parkinson's disease by age, ethnic group, and sex in northern Manhattan, 1988-1993. Am. J. Epidemiol. (1995) 142:820-827.
-
(1995)
Am. J. Epidemiol
, vol.142
, pp. 820-827
-
-
Mayeux, R.1
Marder, K.2
Cote, L.J.3
-
214
-
-
0034649437
-
Parkinson's disease and parkinsonism in a longitudinal study: Two-fold higher incidence in men
-
ILSA Working Group. Italian Longitudinal Study on Aging
-
BALDERESCHI M, DI CARLO A, ROCCA WA et al.: Parkinson's disease and parkinsonism in a longitudinal study: two-fold higher incidence in men. ILSA Working Group. Italian Longitudinal Study on Aging. Neurology (2000) 55:1358-1363.
-
(2000)
Neurology
, vol.55
, pp. 1358-1363
-
-
Baldereschi, M.1
Di Carlo, A.2
Rocca, W.A.3
-
215
-
-
0031921363
-
Postmenopausal estrogen use and Parkinson's disease with and without dementia
-
MARDER K, TANG MX, ALFARO B et al.: Postmenopausal estrogen use and Parkinson's disease with and without dementia. Neurology (1998) 50:1141-1143.
-
(1998)
Neurology
, vol.50
, pp. 1141-1143
-
-
Marder, K.1
Tang, M.X.2
Alfaro, B.3
-
216
-
-
0033594528
-
The effect of estrogen replacement on early Parkinson's disease
-
SAUNDERS-PULLMAN R, GORDON ELLIOTT J, PARIDES M, FAHN S, SAUNDERS HR, BRESSMAN S: The effect of estrogen replacement on early Parkinson's disease. Neurology (1999) 52:1417-1421.
-
(1999)
Neurology
, vol.52
, pp. 1417-1421
-
-
Saunders-pullman, R.1
Gordon Elliott, J.2
Parides, M.3
Fahn, S.4
Saunders, H.R.5
Bressman, S.6
-
217
-
-
0033693347
-
Estrogen use among nursing home residents with a diagnosis of Parkinson's disease
-
FERNANDEZ HH, LAPANE KL: Estrogen use among nursing home residents with a diagnosis of Parkinson's disease. Mov. Disord. (2000) 15:1119-1124.
-
(2000)
Mov. Disord
, vol.15
, pp. 1119-1124
-
-
Fernandez, H.H.1
Lapane, K.L.2
-
218
-
-
0033551482
-
Short-term effects of high dose 17β-estradiol in postmenopausal PD patients: A crossover study
-
BLANCHET PJ, FANG J, HYLAND K, ARNOLD LA, MOURADIAN MM, CHASE TN: Short-term effects of high dose 17β-estradiol in postmenopausal PD patients: a crossover study. Neurology (1999) 53:91-95.
-
(1999)
Neurology
, vol.53
, pp. 91-95
-
-
Blanchet, P.J.1
Fang, J.2
Hyland, K.3
Arnold, L.A.4
Mouradian, M.M.5
Chase, T.N.6
-
219
-
-
0034720817
-
Estrogen improves motor disability in parkinsonian postmenopausal women with motor fluctuations
-
TSANG KL, HO SL, LO SK: Estrogen improves motor disability in parkinsonian postmenopausal women with motor fluctuations. Neurology (2000) 54:2292-2298.
-
(2000)
Neurology
, vol.54
, pp. 2292-2298
-
-
Tsang, K.L.1
Ho, S.L.2
Lo, S.K.3
-
220
-
-
0034551768
-
Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: Implications for Parkinson's disease and memory
-
LERANTH C, ROTH RH, ELSWORTH JD, NAFTOLIN E HORVATH TL, REDMOND DE: Estrogen is essential for maintaining nigrostriatal dopamine neurons in primates: implications for Parkinson's disease and memory. J. Neurosci. (2000) 20:8604-8609.
-
(2000)
J. Neurosci
, vol.20
, pp. 8604-8609
-
-
Leranth, C.1
Roth, R.H.2
Elsworth, J.D.3
Naftolin, E.4
Horvath, T.L.5
Redmond, D.E.6
-
221
-
-
0031868194
-
The impact of gender and estrogen on striatal dopaminergic neurotoxicity
-
MILLER DB, ALI SF, O'CALLAGHAN JP, LAWS SC: The impact of gender and estrogen on striatal dopaminergic neurotoxicity. Ann. NY Acad. Sci. (1998) 844:153-165.
-
(1998)
Ann. NY Acad. Sci
, vol.844
, pp. 153-165
-
-
Miller, D.B.1
Ali, S.F.2
O'callaghan, J.P.3
Laws, S.C.4
-
222
-
-
0034743548
-
Neuroprotective properties of 17β-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice
-
CALLIER S, MORISSETTE M, GRANDBOIS M, PELAPRAT D, DI PAOLO T: Neuroprotective properties of 17β-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice. Synapse (2001) 41:131-138.
-
(2001)
Synapse
, vol.41
, pp. 131-138
-
-
Callier, S.1
Morissette, M.2
Grandbois, M.3
Pelaprat, D.4
Di Paolo, T.5
-
223
-
-
0033541016
-
Creatine monohydrate increases strength in patients with neuromuscular disease
-
TARNOPOLSKY MA, MARTIN J: Creatine monohydrate increases strength in patients with neuromuscular disease. Neurology (1999) 52:854-857.
-
(1999)
Neurology
, vol.52
, pp. 854-857
-
-
Tarnopolsky, M.A.1
Martin, J.2
-
224
-
-
0035002174
-
Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders
-
TARNOPOLSKY MA, BEAL MF: Potential for creatine and other therapies targeting cellular energy dysfunction in neurological disorders. Ann. Neurol. (2001) 49:561-574.
-
(2001)
Ann. Neurol
, vol.49
, pp. 561-574
-
-
Tarnopolsky, M.A.1
Beal, M.F.2
-
225
-
-
0032914740
-
Creatine and cyclocreatine attenuate MPTP neurotoxicity
-
MATTHEWS RT FERRANTE RJ, KLIVENYI P et al.: Creatine and cyclocreatine attenuate MPTP neurotoxicity. Exp. Neurol. (1999) 157:142-149.
-
(1999)
Exp. Neurol
, vol.157
, pp. 142-149
-
-
Matthews, R.T.1
Ferrante, R.J.2
Klivenyi, P.3
-
226
-
-
0029844003
-
Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons
-
HANTRAYE P, BROUILLET E, FERRANTE R et al.: Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nat. Med. (1996) 2:1017-1021.
-
(1996)
Nat. Med
, vol.2
, pp. 1017-1021
-
-
Hantraye, P.1
Brouillet, E.2
Ferrante, R.3
-
227
-
-
0033608739
-
Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase
-
FERRANTE RJ, HANTRAYE P, BROUILLET E, BEAL MF: Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase. Brain Res. (1999) 823:177-182.
-
(1999)
Brain Res
, vol.823
, pp. 177-182
-
-
Ferrante, R.J.1
Hantraye, P.2
Brouillet, E.3
Beal, M.F.4
-
228
-
-
0033533081
-
Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: Protective effects of peroxynitrite decomposition catalyst
-
IMAM SZ, CROW JP, NEWPORT GD, ISLAM F, SLIKKER W, ALI SF: Methamphetamine generates peroxynitrite and produces dopaminergic neurotoxicity in mice: protective effects of peroxynitrite decomposition catalyst. Brain Res. (1999) 837:15-21.
-
(1999)
Brain Res
, vol.837
, pp. 15-21
-
-
Imam, S.Z.1
Crow, J.P.2
Newport, G.D.3
Islam, F.4
Slikker, W.5
Ali, S.F.6
-
229
-
-
0032478182
-
Peroxynitrite decomposition catalysts: Therapeutics for peroxynitrite-mediated pathology
-
SALVEMINI D, WANG ZQ, STERN MK, CURRIE MG, MISKO TP: Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology. Proc. Natl. Acad. Sci. USA (1998) 95:2659-2663.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2659-2663
-
-
Salvemini, D.1
Wang, Z.Q.2
Stern, M.K.3
Currie, M.G.4
Misko, T.P.5
-
230
-
-
0034939055
-
Methamphetamine-induced dopaminergic neurotoxicity: Role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts
-
IMAM SZ, EL-YAZAL J, NEWPORT GD et al.: Methamphetamine-induced dopaminergic neurotoxicity: role of peroxynitrite and neuroprotective role of antioxidants and peroxynitrite decomposition catalysts. Ann. NY Acad. Sci. (2001) 939:366-380.
-
(2001)
Ann. NY Acad. Sci
, vol.939
, pp. 366-380
-
-
Imam, S.Z.1
El-Yazal, J.2
Newport, G.D.3
-
231
-
-
0033994250
-
Ebselen: Prospective therapy for cerebral ischaemia
-
PARNHAM M, SIES H: Ebselen: prospective therapy for cerebral ischaemia. Expert Opin. Investig. Drugs (2000) 9:607-619.
-
(2000)
Expert Opin. Investig. Drugs
, vol.9
, pp. 607-619
-
-
Parnham, M.1
Sies, H.2
-
232
-
-
0030000830
-
The reaction of 2-(methylseleno)benzanilide with peroxynitrite
-
MASUMOTO H, SIES H. The reaction of 2-(methylseleno)benzanilide with peroxynitrite. Chem. Res. Toxicol. (1996) 9:1057-1062.
-
(1996)
Chem. Res. Toxicol
, vol.9
, pp. 1057-1062
-
-
Masumoto, H.1
Sies, H.2
-
233
-
-
0033669158
-
The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease
-
MOUSSAOUI S, OBINU MC, DANIEL N, REIBAUD M, BLANCHARD V, IMPERATO A: The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease. Exp. Neural. (2000) 166:235-245.
-
(2000)
Exp. Neural
, vol.166
, pp. 235-245
-
-
Moussaoui, S.1
Obinu, M.C.2
Daniel, N.3
Reibaud, M.4
Blanchard, V.5
Imperato, A.6
-
234
-
-
0032964009
-
Novel free radical spin traps protect against malonate and MPTP neurotoxicity
-
MATTHEWS RT, KLIVENYI P, MUELLER G et al.: Novel free radical spin traps protect against malonate and MPTP neurotoxicity. Exp. Neurol. (1999) 157:120-126.
-
(1999)
Exp. Neurol
, vol.157
, pp. 120-126
-
-
Matthews, R.T.1
Klivenyi, P.2
Mueller, G.3
-
235
-
-
0344938398
-
Treatment with the spin-trap agent α-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons
-
KARLSSON J, EMGARD M, ROSENBLAD C, BRUNDIN P: Treatment with the spin-trap agent α-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons. Brain Res. (1998) 805:155-168.
-
(1998)
Brain Res
, vol.805
, pp. 155-168
-
-
Karlsson, J.1
Emgard, M.2
Rosenblad, C.3
Brundin, P.4
-
236
-
-
0033956502
-
The protective effects of PBN against MPTP toxicity are independent of hydroxyl radical trapping
-
FERGER B, TEISMANN P, EARL CD, KUSCHINSKY K, OERTEL WH: The protective effects of PBN against MPTP toxicity are independent of hydroxyl radical trapping. Pharmacol. Biochem. Behav. (2000) 65:425-431.
-
(2000)
Pharmacol. Biochem. Behav
, vol.65
, pp. 425-431
-
-
Ferger, B.1
Teismann, P.2
Earl, C.D.3
Kuschinsky, K.4
Oertel, W.H.5
-
237
-
-
0034851553
-
Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
-
LEVITES Y, WEINREB O, MAOR G, YOUDIM MB, MANDEL S: Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration. J. Neurochem. (2001) 78:1073-1082.
-
(2001)
J. Neurochem
, vol.78
, pp. 1073-1082
-
-
Levites, Y.1
Weinreb, O.2
Maor, G.3
Youdim, M.B.4
Mandel, S.5
-
238
-
-
0035807932
-
Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease
-
DATLA KP, CHRISTIDOU M, WIDMER WW, ROOPRAI HK, DEXTER DT: Tissue distribution and neuroprotective effects of citrus flavonoid tangeretin in a rat model of Parkinson's disease. Neuroreport (2001) 12:3871-3875.
-
(2001)
Neuroreport
, vol.12
, pp. 3871-3875
-
-
Datla, K.P.1
Christidou, M.2
Widmer, W.W.3
Rooprai, H.K.4
Dexter, D.T.5
-
240
-
-
0030606143
-
Melatonin is protective against MPTP-induced striatal and hippocampal lesions
-
ACUNA-CASTROVIEJO D, COTOMONTES A, GAIA MONTI M, ORTIZ GG, REITER RJ: Melatonin is protective against MPTP-induced striatal and hippocampal lesions. Life Sci. (1997) 60: PL23-29.
-
(1997)
Life Sci
, vol.60
-
-
Acuna-Castroviejo, D.1
Cotomontes, A.2
Gaia Monti, M.3
Ortiz, G.G.4
Reiter, R.J.5
-
241
-
-
0035032635
-
Protective role of melatonin against MPTP-induced mouse brain cell DNA fragmentation and apoptosis in vivo
-
ORTIZ GG, CRESPO-LOPEZ ME, MORAN-MOGUEL C, GARCIA JJ, REITER RJ, ACUNA-CASTROVIEJO D: Protective role of melatonin against MPTP-induced mouse brain cell DNA fragmentation and apoptosis in vivo. Neuroendocrinol. Lett. (2001) 22:101-108.
-
(2001)
Neuroendocrinol. Lett
, vol.22
, pp. 101-108
-
-
Ortiz, G.G.1
Crespo-Lopez, M.E.2
Moran-Moguel, C.3
Garcia, J.J.4
Reiter, R.J.5
Acuna-Castroviejo, D.6
-
242
-
-
0035170284
-
Melatonin protects against 6-OHDA-induced neurotoxicity in rats: A role for mitochondrial complex I activity
-
DABBENI-SALA F, DI SANTO S, FRANCESCHINI D, SKAPER SD, GIUSTI P: Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex I activity. FASEB J. (2001) 15:164-170.
-
(2001)
FASEB J
, vol.15
, pp. 164-170
-
-
Dabbeni-Sala, F.1
Di Santo, S.2
Franceschini, D.3
Skaper, S.D.4
Giusti, P.5
-
243
-
-
0035824271
-
Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway
-
MORGAN WW, NELSON JF: Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway. Brain Res. (2001) 921:115-121.
-
(2001)
Brain Res
, vol.921
, pp. 115-121
-
-
Morgan, W.W.1
Nelson, J.F.2
-
244
-
-
0032973751
-
A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease
-
WILLIS GL, ARMSTRONG SM: A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease. Physiol. Behav. (1999) 66:785-795.
-
(1999)
Physiol. Behav
, vol.66
, pp. 785-795
-
-
Willis, G.L.1
Armstrong, S.M.2
-
246
-
-
0344528794
-
The inflammatory reaction following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication in mouse
-
KURKOWSKA-JASTRZEBSKA I, WRONSKA A, KOHUTNICKA M, CZLONKOWSKI A, CZLONKOWSKA A: The inflammatory reaction following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxication in mouse. Exp. Neurol. (1999) 156:50-61.
-
(1999)
Exp. Neurol
, vol.156
, pp. 50-61
-
-
Kurkowska-Jastrzebska, I.1
Wronska, A.2
Kohutnicka, M.3
Czlonkowski, A.4
Czlonkowska, A.5
-
247
-
-
0032862588
-
Salicylate protects against MPTP-induced impairments in dopaminergic neurotransmission at the striatal and nigral level in mice
-
FERGER B, TEISMANN P, EARL CD, KUSCHINSKY K, OERTEL WH: Salicylate protects against MPTP-induced impairments in dopaminergic neurotransmission at the striatal and nigral level in mice. Naunyn Schmiedebergs Arch. Pharmacol. (1999) 360:256-261.
-
(1999)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.360
, pp. 256-261
-
-
Ferger, B.1
Teismann, P.2
Earl, C.D.3
Kuschinsky, K.4
Oertel, W.H.5
-
248
-
-
0035134830
-
Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease
-
TEISMANN P, FERGER B: Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease. Synapse (2001) 39:167-174.
-
(2001)
Synapse
, vol.39
, pp. 167-174
-
-
Teismann, P.1
Ferger, B.2
-
249
-
-
0032190264
-
Cyclooxygenase and inflammation in Alzheimer's disease: Experimental approaches and clinical interventions
-
PASINETTI GM: Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. J. Neurosci. Res. (1998) 54:1-6.
-
(1998)
J. Neurosci. Res
, vol.54
, pp. 1-6
-
-
Pasinetti, G.M.1
-
250
-
-
0031954732
-
Levodopa therapy: Consequences of the nonphysiologic replacement of dopamine
-
CHASE TN: Levodopa therapy: consequences of the nonphysiologic replacement of dopamine. Neurology (1998) 50(5 Suppl. 5):S17-23.
-
(1998)
Neurology
, vol.50
, Issue.5 SUPPL. 5
-
-
Chase, T.N.1
-
251
-
-
0035085603
-
Effects of R- and S-apomorphine on MPTP-induced nigrostriatal dopamine neuronal loss
-
GRUNBLATT E, MANDEL S, MAOR G, YOUDIM MB: Effects of R- and S-apomorphine on MPTP-induced nigrostriatal dopamine neuronal loss. J. Neurochem. (2001) 77:146-156.
-
(2001)
J. Neurochem
, vol.77
, pp. 146-156
-
-
Grunblatt, E.1
Mandel, S.2
Maor, G.3
Youdim, M.B.4
-
252
-
-
0035853485
-
Dose-dependent protective effects of apomorphine against methamphetamine-induced nigrostriatal damage
-
FORNAI F, BATTAGLIA G, GESI M, ORZI F, NICOLETTI F, RUGGIERI S: Dose-dependent protective effects of apomorphine against methamphetamine-induced nigrostriatal damage. Brain Res. (2001) 898:27-35.
-
(2001)
Brain Res
, vol.898
, pp. 27-35
-
-
Fornai, F.1
Battaglia, G.2
Gesi, M.3
Orzi, F.4
Nicoletti, F.5
Ruggieri, S.6
-
253
-
-
0035184877
-
Toxic effects of apomorphine on rat cultured neurons and glial C6 cells, and protection with antioxidants
-
DOS SANTOS EL-BACHA R, DAVAL J, KOZIEL V, NETTER P, MINN A: Toxic effects of apomorphine on rat cultured neurons and glial C6 cells, and protection with antioxidants. Biochem. Pharmacol. (2001) 61:73-85.
-
(2001)
Biochem. Pharmacol
, vol.61
, pp. 73-85
-
-
Dos Santos El-Bacha, R.1
Daval, J.2
Koziel, V.3
Netter, P.4
Minn, A.5
-
254
-
-
0035936962
-
SKF-38393, a dopamine receptor agonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
-
MURALIKRISHNAN D, EBADI M: SKF-38393, a dopamine receptor agonist, attenuates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Brain Res. (2001) 892:241-247.
-
(2001)
Brain Res
, vol.892
, pp. 241-247
-
-
Muralikrishnan, D.1
Ebadi, M.2
-
255
-
-
0033554203
-
Dopamine D2 receptor mediated antioxiclant and neuroprotective effects of ropinirole, a dopamine agonist
-
IIDA M, MIYAZAKI I, TANAKA K, KABUTO H, IWATA-ICHIKAWA E, OGAWA N: Dopamine D2 receptor mediated antioxiclant and neuroprotective effects of ropinirole, a dopamine agonist. Brain Res. (1999) 838:51-59.
-
(1999)
Brain Res
, vol.838
, pp. 51-59
-
-
Iida, M.1
Miyazaki, I.2
Tanaka, K.3
Kabuto, H.4
Iwata-ichikawa, E.5
Ogawa, N.6
-
256
-
-
0034668920
-
Neuroprotective role of dopamine against hippocampal cell death
-
BOZZI Y, VALLONE D, BORRELLI E: Neuroprotective role of dopamine against hippocampal cell death. J. Neurosci. (2000) 20:8643-8649.
-
(2000)
J. Neurosci
, vol.20
, pp. 8643-8649
-
-
Bozzi, Y.1
Vallone, D.2
Borrelli, E.3
-
257
-
-
0035124718
-
Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor deficient mice
-
CEPEDA C, HURST RS, ALTEMUS KL et al.: Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor deficient mice. J. Neurophysiol. (2001) 85:659-670.
-
(2001)
J. Neurophysiol
, vol.85
, pp. 659-670
-
-
Cepeda, C.1
Hurst, R.S.2
Altemus, K.L.3
-
258
-
-
0035968070
-
Neuroprotective effects of pramipexole in young and aged MPTP-treated mice
-
ANDERSON DW, NEAVIN T, SMITH JA, SCHNEIDER JS: Neuroprotective effects of pramipexole in young and aged MPTP-treated mice. Brain Res. (2001) 905:44-53.
-
(2001)
Brain Res
, vol.905
, pp. 44-53
-
-
Anderson, D.W.1
Neavin, T.2
Smith, J.A.3
Schneider, J.S.4
-
259
-
-
0035882457
-
The activation of dopamine D4 receptors inhibits oxidative stress-induced nerve cell death
-
ISHIGE K, CHEN Q, SAGARA Y, SCHUBERT D: The activation of dopamine D4 receptors inhibits oxidative stress-induced nerve cell death. J. Neurosci. (2001) 21:6069-6076.
-
(2001)
J. Neurosci
, vol.21
, pp. 6069-6076
-
-
Ishige, K.1
Chen, Q.2
Sagara, Y.3
Schubert, D.4
-
261
-
-
18544400323
-
Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo
-
SCHERZINGER E, LURZ R, TURMAINE M et al.: Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo. Cell(1997) 90:549-558.
-
(1997)
Cell
, vol.90
, pp. 549-558
-
-
Scherzinger, E.1
Lurz, R.2
Turmaine, M.3
-
262
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DIFIGLIA M, SAPP E, CHASE KO et al.: Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science (1997) 277:1990 1993.
-
(1997)
Science
, vol.277
, pp. 1990-1993
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.O.3
-
263
-
-
0033080367
-
Glutamine repeats and neurodegenerative diseases: Molecular aspects
-
PERUTZ MF: Glutamine repeats and neurodegenerative diseases: molecular aspects. Trends Biochem. Sci. (1999) 24:58-63.
-
(1999)
Trends Biochem. Sci
, vol.24
, pp. 58-63
-
-
Perutz, M.F.1
-
264
-
-
0034737299
-
Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
-
YAMAMOTO A, LUCAS JJ, HEN R: Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease. Cell (2000) 101:57-66.
-
(2000)
Cell
, vol.101
, pp. 57-66
-
-
Yamamoto, A.1
Lucas, J.J.2
Hen, R.3
-
265
-
-
0035937523
-
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
-
NUCIFORA EC, SASAKI M, PETERS ME et al.: Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science (2001) 291:2423-2428.
-
(2001)
Science
, vol.291
, pp. 2423-2428
-
-
Nucifora, E.C.1
Sasaki, M.2
Peters, M.E.3
-
266
-
-
0034123691
-
Mechanisms of neurodegenerative disorders: Part 1: Protein Aggregates
-
WOLOZIN B, BEHL C: Mechanisms of neurodegenerative disorders: Part 1: Protein Aggregates. Arch. Neurol. (2000) 57:793-796.
-
(2000)
Arch. Neurol
, vol.57
, pp. 793-796
-
-
Wolozin, B.1
Behl, C.2
-
267
-
-
0034051284
-
Mechanisms of neurodegenerative disorders: Part 2: Control of cell death
-
WOLOZIN B, BEHL C: Mechanisms of neurodegenerative disorders: Part 2: Control of cell death. Arch. Neurol. (2000) 57:801-804.
-
(2000)
Arch. Neurol
, vol.57
, pp. 801-804
-
-
Wolozin, B.1
Behl, C.2
-
268
-
-
0034329159
-
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
-
GUSELLA JF, MACDONALD ME: Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease. Nat. Rev. Neurosci. (2001) 1:109-115.
-
(2001)
Nat. Rev. Neurosci
, vol.1
, pp. 109-115
-
-
Gusella, J.F.1
Macdonald, M.E.2
-
269
-
-
0033914874
-
No evidence for increased oxidative damage to lipids, proteins, or DNA in Huntington's disease
-
ALAM ZI, HALLIWELL B, JENNER P: No evidence for increased oxidative damage to lipids, proteins, or DNA in Huntington's disease. J. Neurochem. (2000) 75:840-846.
-
(2000)
J. Neurochem
, vol.75
, pp. 840-846
-
-
Alam, Z.I.1
Halliwell, B.2
Jenner, P.3
-
270
-
-
0031044805
-
Energy metabolism defects in Huntington's disease and effects of coenzyme Q10
-
KOROSHETZ WJ, JENKINS BG, ROSEN BR, BEAL MF: Energy metabolism defects in Huntington's disease and effects of coenzyme Q10. Ann. Neurol. (1997) 41:160-165.
-
(1997)
Ann. Neurol
, vol.41
, pp. 160-165
-
-
Koroshetz, W.J.1
Jenkins, B.G.2
Rosen, B.R.3
Beal, M.F.4
-
271
-
-
0029988363
-
Assessment of coenzyme Q10 tolerability in Huntington's disease
-
FEIGIN A, KIEBURTZ K, COMO P et al.: Assessment of coenzyme Q10 tolerability in Huntington's disease. Mov. Disord. (1996) 11:321-323.
-
(1996)
Mov. Disord
, vol.11
, pp. 321-323
-
-
Feigin, A.1
Kieburtz, K.2
Como, P.3
-
272
-
-
9544255791
-
A controlled trial of idebenone in Huntington's disease
-
RANEN NG, PEYSER CE, COYLE JT et al.: A controlled trial of idebenone in Huntington's disease. Mov. Disord. (1996) 11:549-554.
-
(1996)
Mov. Disord
, vol.11
, pp. 549-554
-
-
Ranen, N.G.1
Peyser, C.E.2
Coyle, J.T.3
-
273
-
-
85009226418
-
A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease
-
HUNTINGTON STUDY GROUP
-
HUNTINGTON STUDY GROUP: A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology (2001) 57:397-404.
-
(2001)
Neurology
, vol.57
, pp. 397-404
-
-
-
274
-
-
0344625374
-
Safety and tolerability of the free-radical scavenger OPC-14117 in Huntington's disease
-
HUNTINGTON STUDY GROUP
-
HUNTINGTON STUDY GROUP: Safety and tolerability of the free-radical scavenger OPC-14117 in Huntington's disease. Neurology (1998) 50:1366-1373.
-
(1998)
Neurology
, vol.50
, pp. 1366-1373
-
-
-
275
-
-
0032191183
-
Chronic exposure to MPTP as a primate model of progressive parkinsonism: A pilot study with a free radical scavenger
-
BLANCHET PJ, KONITSIOTIS S, HYLAND K, ARNOLD LA, PETTIGREW KD, CHASE TN: Chronic exposure to MPTP as a primate model of progressive parkinsonism: a pilot study with a free radical scavenger. Exp. Neurol. (1998) 153:214-222.
-
(1998)
Exp. Neurol
, vol.153
, pp. 214-222
-
-
Blanchet, P.J.1
Konitsiotis, S.2
Hyland, K.3
Arnold, L.A.4
Pettigrew, K.D.5
Chase, T.N.6
-
276
-
-
0030887358
-
Protective effect of a novel free radical scavenger, OPC-14117, on wobbler mouse motor neuron disease
-
ABE K, MORITA S, KIKUCHI T, ITOYAMA Y: Protective effect of a novel free radical scavenger, OPC-14117, on wobbler mouse motor neuron disease. J. Neurosci. Res. (1997) 48:63-70.
-
(1997)
J. Neurosci. Res
, vol.48
, pp. 63-70
-
-
Abe, K.1
Morita, S.2
Kikuchi, T.3
Itoyama, Y.4
-
277
-
-
0028856571
-
Trial of D-α-tocopherol in Huntington's disease
-
PEYSER CE, FOLSTEIN M, CHASE GA et al.: Trial of D-α-tocopherol in Huntington's disease. Am. J. Psychiatry (1995) 152:1771-1775.
-
(1995)
Am. J. Psychiatry
, vol.152
, pp. 1771-1775
-
-
Peyser, C.E.1
Folstein, M.2
Chase, G.A.3
-
278
-
-
0032815680
-
Replicating Huntington's disease phenotype in experimental animals
-
BROUILLET E, CONDE F, BEAL MF, HANTRAYE P: Replicating Huntington's disease phenotype in experimental animals. Prog. Neurobiol. (1999) 59:427-468.
-
(1999)
Prog. Neurobiol
, vol.59
, pp. 427-468
-
-
Brouillet, E.1
Conde, F.2
Beal, M.F.3
Hantraye, P.4
-
279
-
-
0027448161
-
Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid
-
BROUILLET E, JENKINS BG, HYMAN BT et al.: Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid. J. Neurochem. (1993) 60:356-359.
-
(1993)
J. Neurochem
, vol.60
, pp. 356-359
-
-
Brouillet, E.1
Jenkins, B.G.2
Hyman, B.T.3
-
280
-
-
0034628981
-
3-Nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: Insights into Huntington's disease
-
LA FONTAINE MA, GEDDES JW, BANKS A, BUTTERFIELD DA: 3-Nitropropionic acid induced in vivo protein oxidation in striatal and cortical synaptosomes: insights into Huntington's disease. Brain Res. (2000) 858:356-362.
-
(2000)
Brain Res
, vol.858
, pp. 356-362
-
-
La Fontaine, M.A.1
Geddes, J.W.2
Banks, A.3
Butterfield, D.A.4
-
281
-
-
0031964359
-
Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease
-
MATTHEWS RT, YANG L, JENKINS BG et al.: Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease. J. Neurosci. (1998) 18:156-163.
-
(1998)
J. Neurosci
, vol.18
, pp. 156-163
-
-
Matthews, R.T.1
Yang, L.2
Jenkins, B.G.3
-
282
-
-
0034717594
-
Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats
-
SHEAR DA, HAIK KL, DUNBAR GL: Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats. Neuroreport (2000) 11:1833-1837.
-
(2000)
Neuroreport
, vol.11
, pp. 1833-1837
-
-
Shear, D.A.1
Haik, K.L.2
Dunbar, G.L.3
-
283
-
-
0035968856
-
Lipoic acid improves survival in transgenic mouse models of Huntington's disease
-
ANDREASSEN OA, FERRANTE RJ, DEDEOGLU A, BEAL ME: Lipoic acid improves survival in transgenic mouse models of Huntington's disease. Neuroreport (2001) 12:3371-3373.
-
(2001)
Neuroreport
, vol.12
, pp. 3371-3373
-
-
Andreassen, O.A.1
Ferrante, R.J.2
Dedeoglu, A.3
Beal, M.E.4
-
284
-
-
0030580581
-
Effects of α-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid
-
NAKAO N, BRUNDIN P: Effects of α-phenyl-tert-butyl nitrone on neuronal survival and motor function following intrastriatal injections of quinolinate or 3-nitropropionic acid. Neuroscience (1997) 76:749-761.
-
(1997)
Neuroscience
, vol.76
, pp. 749-761
-
-
Nakao, N.1
Brundin, P.2
-
285
-
-
0033396459
-
Protective effect of L-carnitine in the neurotoxicity induced by the mitochondrial inhibitor 3-nitropropionic acid (3-NPA)
-
BINIENDA Z, JOHNSON JR, TYLER-HASHEMI AA et al.: Protective effect of L-carnitine in the neurotoxicity induced by the mitochondrial inhibitor 3-nitropropionic acid (3-NPA). Ann. NY Acad. Sci. (1999) 890:173-178.
-
(1999)
Ann. NY Acad. Sci
, vol.890
, pp. 173-178
-
-
Binienda, Z.1
Johnson, J.R.2
Tyler-Hashemi, A.A.3
-
286
-
-
0034698951
-
Pyruvate protects against 3-nitropropionic acid induced neurotoxicity in corticostriatal slice cultures
-
GRAMSBERGEN JB, SANDBERG M, KORNBLIT B, ZIMMER J: Pyruvate protects against 3-nitropropionic acid induced neurotoxicity in corticostriatal slice cultures. Neuroreport (2000) 11:2743-2747.
-
(2000)
Neuroreport
, vol.11
, pp. 2743-2747
-
-
Gramsbergen, J.B.1
Sandberg, M.2
Kornblit, B.3
Zimmer, J.4
-
287
-
-
0034624968
-
D-β-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
-
KASHIWAYA Y, TAKESHIMA T, MORI N, NAKASHIMA K, CLARKE K, VEECH RL: D-β-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease. Proc. Natl. Acad. Sci. USA (2000) 97:5440-5444.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5440-5444
-
-
Kashiwaya, Y.1
Takeshima, T.2
Mori, N.3
Nakashima, K.4
Clarke, K.5
Veech, R.L.6
-
288
-
-
0034844219
-
Ketone bodies, potential therapeutic uses
-
VEECH RL, CHANCE B, KASHIWAYA Y, LARDY HA, CAHILL GF: Ketone bodies, potential therapeutic uses. IUBMB Life (2001) 51:241-247.
-
(2001)
IUBMB Life
, vol.51
, pp. 241-247
-
-
Veech, R.L.1
Chance, B.2
Kashiwaya, Y.3
Lardy, H.A.4
Cahill, G.F.5
-
289
-
-
0034848432
-
Taurine increases rat survival and reduces striatal damage caused by 3-nitropropionic acid
-
RIVAS-ARANCIBIA S, RODRIGUEZ AI, ZIGOVA T et al.: Taurine increases rat survival and reduces striatal damage caused by 3-nitropropionic acid. Int. J. Neurosci. (2001) 108:55-67.
-
(2001)
Int. J. Neurosci
, vol.108
, pp. 55-67
-
-
Rivas-Arancibia, S.1
Rodriguez, A.I.2
Zigova, T.3
-
290
-
-
0023697974
-
The antioxidant action of taurine, hypotaurine and their metabolic precursors
-
ARUOMA OI, HALLIWELL B, HOEY BM, BUTLER J: The antioxidant action of taurine, hypotaurine and their metabolic precursors. Biochem. J. (1988) 256:251-255.
-
(1988)
Biochem. J
, vol.256
, pp. 251-255
-
-
Aruoma, O.I.1
Halliwell, B.2
Hoey, B.M.3
Butler, J.4
-
291
-
-
0033769186
-
Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: Evidence for a mitochondrial pathway independent of the permeability transition
-
RODRIGUES CM, STIEERS CL, KEENE CD et al.: Tauroursodeoxycholic acid partially prevents apoptosis induced by 3-nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition. J. Neurochem. (2000) 75:2368-2379.
-
(2000)
J. Neurochem
, vol.75
, pp. 2368-2379
-
-
Rodrigues, C.M.1
Stieers, C.L.2
Keene, C.D.3
-
292
-
-
0010957637
-
Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice
-
HELLER-STILB B, VAN ROEYEN C, RASCHER K et al.: Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice. FASEB J. (2001) 15:42-59.
-
(2001)
FASEB J
, vol.15
, pp. 42-59
-
-
Heller-Stilb, B.1
Van Roeyen, C.2
Rascher, K.3
-
293
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
ROSEN DR, SIDDIQUE T, PATTERSON D et al.: Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature (1993) 362:59-62.
-
(1993)
Nature
, vol.362
, pp. 9-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
294
-
-
0033856830
-
Recent advances in amyotrophic lateral sclerosis
-
AL-CHALABI A, LEIGH PN: Recent advances in amyotrophic lateral sclerosis. Curr. Opin. Neurol. (2000) 13:397-405.
-
(2000)
Curr. Opin. Neurol
, vol.13
, pp. 397-405
-
-
Al-Chalabi, A.1
Leigh, P.N.2
-
295
-
-
0033797469
-
Mortality in a population with long-term exposure to inorganic selenium via drinking water
-
VINCETI M, NACCI G, ROCCHI E et al.: Mortality in a population with long-term exposure to inorganic selenium via drinking water. J. Clin. Epidemiol. (2000) 53:1062-1068.
-
(2000)
J. Clin. Epidemiol
, vol.53
, pp. 1062-1068
-
-
Vinceti, M.1
Nacci, G.2
Rocchi, E.3
-
296
-
-
0034650162
-
Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. II. Diet
-
NELSON LM, MATKIN C, LONGSTRETH WT, MCGUIRE V: Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. II. Diet. Am. J. Epidemiol. (2000) 151:164-173.
-
(2000)
Am. J. Epidemiol
, vol.151
, pp. 164-173
-
-
Nelson, L.M.1
Matkin, C.2
Longstreth, W.T.3
Mcguire, V.4
-
297
-
-
0034650153
-
Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. I. Cigarette smoking and alcohol consumption
-
NELSON LM, MCGUIRE V, LONGSTRETH WT, MATKIN C: Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. I. Cigarette smoking and alcohol consumption. Am. J. Epidemiol. (2000) 151:156-163.
-
(2000)
Am. J. Epidemiol
, vol.151
, pp. 156-163
-
-
Nelson, L.M.1
Mcguire, V.2
Longstreth, W.T.3
Matkin, C.4
-
298
-
-
0030927253
-
Transgenic animal models of familial amyotrophic lateral sclerosis
-
GURNEY ME: Transgenic animal models of familial amyotrophic lateral sclerosis. J. Neurol. (1997) 244(Suppl. 2):S15-S20.
-
(1997)
J. Neurol
, vol.244
, Issue.SUPPL. 2
-
-
Gurney, M.E.1
-
299
-
-
0030806228
-
Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant
-
BRUIJN LI, BEAL MF, BECHER MW et al.: Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant. Proc. Natl. Acad. Sci. USA (1997) 94:7606-7611.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7606-7611
-
-
Bruijn, L.I.1
Beal, M.F.2
Becher, M.W.3
-
300
-
-
0034060692
-
What transgenic mice tell us about neurodegenerative disease
-
GURNEY ME: What transgenic mice tell us about neurodegenerative disease. Bioessays (2000) 22:297-304.
-
(2000)
Bioessays
, vol.22
, pp. 297-304
-
-
Gurney, M.E.1
-
301
-
-
0035118930
-
Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: Relevance to Down's syndrome and familial amyotrophic lateral sclerosis
-
LEE M, HYUN D, JENNER P, HALLIWELL B: Effect of overexpression of wild-type and mutant Cu/Zn-superoxide dismutases on oxidative damage and antioxidant defences: relevance to Down's syndrome and familial amyotrophic lateral sclerosis. J. Neurochem. (2001) 76:957-965.
-
(2001)
J. Neurochem
, vol.76
, pp. 957-965
-
-
Lee, M.1
Hyun, D.2
Jenner, P.3
Halliwell, B.4
-
302
-
-
0033749379
-
Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis
-
JOHNSTON JA, DALTON MJ, GURNEY ME, KOPITO RR: Formation of high molecular weight complexes of mutant Cu,Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA (2000) 97:12571-12576.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12571-12576
-
-
Johnston, J.A.1
Dalton, M.J.2
Gurney, M.E.3
Kopito, R.R.4
-
303
-
-
0034031598
-
Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis
-
SHAW PJ, EGGETT CJ: Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis. J. Neurol. (2000) 247(Suppl. 1):117-127.
-
(2000)
J. Neurol
, vol.247
, Issue.SUPPL. 1
, pp. 117-127
-
-
Shaw, P.J.1
Eggett, C.J.2
-
304
-
-
0031864164
-
Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurones
-
PARKES TL, ELIA AJ, DICKINSON D, HILLIKER AJ, PHILLIPS JP, BOULIANNE GL: Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurones. Nat. Genetics (1998) 19:171-174.
-
(1998)
Nat. Genetics
, vol.19
, pp. 171-174
-
-
Parkes, T.L.1
Elia, A.J.2
Dickinson, D.3
Hilliker, A.J.4
Phillips, J.P.5
Boulianne, G.L.6
-
305
-
-
0035947221
-
Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model
-
JUNG C, RONG Y, DOCTROW S, BAUDRY M, MALFROY B, XU Z: Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model. Neurosci. Lett. (2001) 304:157-160.
-
(2001)
Neurosci. Lett
, vol.304
, pp. 157-160
-
-
Jung, C.1
Rong, Y.2
Doctrow, S.3
Baudry, M.4
Malfroy, B.5
Xu, Z.6
-
306
-
-
0033673060
-
Therapeutic benefit of polyamine-modified catalase as a scavenger of hydrogen peroxide and nitric oxide in familial amyotrophic lateral sclerosis transgenics
-
PODUSLO JF, WHELAN SL, CURRAN GL, WENGENACK TM: Therapeutic benefit of polyamine-modified catalase as a scavenger of hydrogen peroxide and nitric oxide in familial amyotrophic lateral sclerosis transgenics. Ann. Neurol. (2000) 48:943-947.
-
(2000)
Ann. Neurol
, vol.48
, pp. 943-947
-
-
Poduslo, J.F.1
Whelan, S.L.2
Curran, G.L.3
Wengenack, T.M.4
-
307
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
GURNEY ME, CUTTING FB, ZHAI P et al.: Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Neurol. (1996) 39:147-157.
-
(1996)
Ann. Neurol
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
-
308
-
-
0035007860
-
A double-blind, lacebo-controlled randomized clinical trial of α-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis
-
ALS riluzole-tocopherol Study Group
-
DESNUELLE C, DIB M, GARREL C, FAVIER A: A double-blind, lacebo-controlled randomized clinical trial of α-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group. Amyotroph. Lateral Scler. Other Motor Neuron Disord. (2001) 2:9-18.
-
(2001)
Amyotroph. Lateral Scler. Other Motor Neuron Disord
, vol.2
, pp. 9-18
-
-
Desnuelle, C.1
Dib, M.2
Garrel, C.3
Favier, A.4
-
309
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
KLIVENYI P, FERRANTE RJ, MATTHEWS RT et al.: Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat. Med. (1999) 5:347-350.
-
(1999)
Nat. Med
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
-
310
-
-
0035051503
-
Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation
-
ANDREASSEN OA, JENKINS BG, DEDEOGLU A et al.: Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. J. Neurochem. (2001) 77:383-390.
-
(2001)
J. Neurochem
, vol.77
, pp. 383-390
-
-
Andreassen, O.A.1
Jenkins, B.G.2
Dedeoglu, A.3
-
311
-
-
0035068202
-
Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice
-
ANDREASSEN OA, DEDEOGLU A, FRIEDLICH A et al.: Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice. Exp. Neurol. (2001) 168:419-424.
-
(2001)
Exp. Neurol
, vol.168
, pp. 419-424
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Friedlich, A.3
-
312
-
-
0033597218
-
Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice
-
NAGANO S, OGAWA Y, YANAGIHARA T, SAKODA S: Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice. Neurosci. Lett. (1999) 265:159-162.
-
(1999)
Neurosci. Lett
, vol.265
, pp. 159-162
-
-
Nagano, S.1
Ogawa, Y.2
Yanagihara, T.3
Sakoda, S.4
-
313
-
-
0034601439
-
N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis
-
ANDREASSEN OA, DEDEOGLU A, KLIVENYI P, BEAL ME, BUSH AI: N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis. Neuroreport (2000) 11:2491-2493.
-
(2000)
Neuroreport
, vol.11
, pp. 2491-2493
-
-
Andreassen, O.A.1
Dedeoglu, A.2
Klivenyi, P.3
Beal, M.E.4
Bush, A.I.5
-
314
-
-
17344393620
-
The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis
-
JAARSMA D, GUCHELAAR HJ, HAASDIJK E, DE JONG JM, HOLSTEGE JC: The antioxidant N-acetylcysteine does not delay disease onset and death in a transgenic mouse model of amyotrophic lateral sclerosis. Ann. Neurol. (1998) 44:293.
-
(1998)
Ann. Neurol
, vol.44
, pp. 293
-
-
Jaarsma, D.1
Guchelaar, H.J.2
Haasdijk, E.3
De Jong, J.M.4
Holstege, J.C.5
-
315
-
-
0029958252
-
Reduction of lower motor neuron degeneration in wobbler mice by N-acetyl-L-cysteine
-
HENDERSON JT, JAVAHERI M, KOPKO S, RODER JC: Reduction of lower motor neuron degeneration in wobbler mice by N-acetyl-L-cysteine. J. Neurosci. (1996) 16:7574-7582.
-
(1996)
J. Neurosci
, vol.16
, pp. 7574-7582
-
-
Henderson, J.T.1
Javaheri, M.2
Kopko, S.3
Roder, J.C.4
-
316
-
-
0029040463
-
Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis
-
LOUWERSE ES, WEVERLING GJ, BOSSUYT PM, MEYJES FE, DE JONG JM: Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis. Arch. Neurol. (1995) 52:559-564.
-
(1995)
Arch. Neurol
, vol.52
, pp. 559-564
-
-
Louwerse, E.S.1
Weverling, G.J.2
Bossuyt, P.M.3
Meyjes, F.E.4
De Jongt, J.M.5
-
317
-
-
0029787291
-
Survival in patients with amyotrophic lateral sclerosis, treated with an a of antioxidants
-
VYTH A, TIMMER JG, BOSSUYT PM, LOUWERSE ES, DE JONG JM: Survival in patients with amyotrophic lateral sclerosis, treated with an a of antioxidants. J. Neurol. Sci. (1996) 139(Suppl.):99-103.
-
(1996)
J. Neurol. Sci
, vol.139
, Issue.SUPPL.
, pp. 99-103
-
-
Vyth, A.1
Timmer, J.G.2
Bossuyt, P.M.3
Louwerse, E.S.4
De Jong, J.M.5
-
318
-
-
0033594249
-
The pharmacokinetics and pharmacodynamics of procysteine in amyotrophic lateral sclerosis
-
CUDKOWICZ ME, SEXTON PM, ELLIS T et al.: The pharmacokinetics and pharmacodynamics of procysteine in amyotrophic lateral sclerosis. Neurology (1999) 52:1492-1494.
-
(1999)
Neurology
, vol.52
, pp. 1492-1494
-
-
Cudkowicz, M.E.1
Sexton, P.M.2
Ellis, T.3
-
319
-
-
0031886591
-
Selegiline is ineffective in a collaborative double-blind, placebo-controlled trial for treatment of amyotrophic lateral sclerosis
-
LANGE DJ, MURPHY PL, DIAMOND B et al.: Selegiline is ineffective in a collaborative double-blind, placebo-controlled trial for treatment of amyotrophic lateral sclerosis. Arch. Neurol. (1998) 55:93-96.
-
(1998)
Arch. Neurol
, vol.55
, pp. 93-96
-
-
Lange, D.J.1
Murphy, P.L.2
Diamond, B.3
-
320
-
-
0035198214
-
Protective activity of aromatic amines and imines against oxidative nerve cell death
-
MOOSMANN B, SKUTELLA T, BEYER K, BEHL C: Protective activity of aromatic amines and imines against oxidative nerve cell death. Biol. Chem. (2001) 382:1601-1612.
-
(2001)
Biol. Chem
, vol.382
, pp. 1601-1612
-
-
Moosmann, B.1
Skutella, T.2
Beyer, K.3
Behl, C.4
-
321
-
-
0034986361
-
Oxidative stress-induced neurodegenerative diseases: The need for antioxidants that penetrate the blood-brain barrier
-
GILGUN-SHERKI Y, MELAMED E, OFFEN D: Oxidative stress-induced neurodegenerative diseases: the need for antioxidants that penetrate the blood-brain barrier. Neuropharmacology (2001) 40:959-975.
-
(2001)
Neuropharmacology
, vol.40
, pp. 959-975
-
-
Gilgun-sherki, Y.1
Melamed, E.2
Offen, D.3
-
322
-
-
0031695039
-
Blood-brain barrier permeation: Molecular parameters governing passive diffusion
-
FISCHER H, GOTTSCHLICH R, SEELIG A: Blood-brain barrier permeation: molecular parameters governing passive diffusion. J. Membrane Biol. (1998) 165:201-211.
-
(1998)
J. Membrane Biol
, vol.165
, pp. 201-211
-
-
Fischer, H.1
Gottschlich, R.2
Seelig, A.3
-
323
-
-
0033825520
-
Cytoprotective antioxidant function of tyrosine and tryptophan residues in transmembrane proteins
-
MOOSMANN B, BEHL C: Cytoprotective antioxidant function of tyrosine and tryptophan residues in transmembrane proteins. Eur. J. Biochem. (2000) 267:5687-5692.
-
(2000)
Eur. J. Biochem
, vol.267
, pp. 5687-5692
-
-
Moosmann, B.1
Behl, C.2
-
324
-
-
0001951156
-
Dietary phenols: Antioxidants for the brain?
-
MOOSMANN B, BEHL C: Dietary phenols: antioxidants for the brain? Nutr. Neurosci. (2000) 3:1-10.
-
(2000)
Nutr. Neurosci
, vol.3
, pp. 1-10
-
-
Moosmann, B.1
Behl, C.2
-
325
-
-
0010607277
-
The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers
-
ALPHA-TOCOPHEROL, BETA-CAROTENE CANCER PREVENTION STUDY GROUP
-
ALPHA-TOCOPHEROL, BETA-CAROTENE CANCER PREVENTION STUDY GROUP: The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers. N. Engl. J. Med. (1994) 330:1029-1035.
-
(1994)
N. Engl. J. Med
, vol.330
, pp. 1029-1035
-
-
-
326
-
-
16144366857
-
β-Carotene takes a collective beating
-
ROWE PM: β-Carotene takes a collective beating. Lancet (1996) 347:249.
-
(1996)
Lancet
, vol.347
, pp. 249
-
-
Rowe, P.M.1
-
327
-
-
0031832079
-
The prevention of cancer
-
AMES BN, GOLD LS: The prevention of cancer. Drug Metab. Rev. (1998) 30:201-223.
-
(1998)
Drug Metab. Rev
, vol.30
, pp. 201-223
-
-
Ames, B.N.1
Gold, L.S.2
-
328
-
-
0034724365
-
Association of vitamin E and C supplement use with cognitive function and dementia in elderly men
-
MASAKI KH, LOSONCZY KG, IZMIRLIAN G et al.: Association of vitamin E and C supplement use with cognitive function and dementia in elderly men. Neurology (2000) 54:1265-1272.
-
(2000)
Neurology
, vol.54
, pp. 1265-1272
-
-
Masaki, K.H.1
Losonczy, K.G.2
Izmirlian, G.3
-
329
-
-
0035101295
-
Nutritional factors in cerebral aging and dementia: Epidemiological arguments for a role of oxidative stress
-
DESCHAMPS V, BARBERGER-GATEAU P, PEUCHANT E, ORGOGOZO JM: Nutritional factors in cerebral aging and dementia: epidemiological arguments for a role of oxidative stress. Neuroepidemiology (2001) 20:7-15.
-
(2001)
Neuroepidemiology
, vol.20
, pp. 7-15
-
-
Deschamps, V.1
Barberger-gateau, P.2
Peuchant, E.3
Orgogozo, J.M.4
-
331
-
-
0030057197
-
Oxidative stress, nutrition and health. Experimental strategies for optimization of nutritional antioxidant intake in humans
-
HALLIWELL B: Oxidative stress, nutrition and health. Experimental strategies for optimization of nutritional antioxidant intake in humans. Free Radic. Res. (1996) 25:57-74.
-
(1996)
Free Radic. Res
, vol.25
, pp. 57-74
-
-
Halliwell, B.1
-
332
-
-
0034176645
-
The antioxidant paradox
-
HALLIWELL B: The antioxidant paradox. Lancet (2000) 335:1179-1180.
-
(2000)
Lancet
, vol.335
, pp. 1179-1180
-
-
Halliwell, B.1
-
333
-
-
0035098686
-
The importance of using scientific principles in the development of medicinal agents from plants
-
TALALAY P, TALALAY P: The importance of using scientific principles in the development of medicinal agents from plants. Acad. Med. (2001) 76:238-247.
-
(2001)
Acad. Med
, vol.76
, pp. 238-247
-
-
Talalay, P.1
Talalay, P.2
-
334
-
-
0032829070
-
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
-
LANGSTON JW, FORNO LS, TETRUD J, REEVES AG, KAPLAN JA, KARLUK D: Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann. Neurol. (1999) 46:598-605.
-
(1999)
Ann. Neurol
, vol.46
, pp. 598-605
-
-
Langston, J.W.1
Forno, L.S.2
Tetrud, J.3
Reeves, A.G.4
Kaplan, J.A.5
Karluk, D.6
-
335
-
-
0028020365
-
Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions
-
VINGERHOETS FJ, SNOW BJ, TETRUD JW, LANGSTON JW, SCHULZER M, CALNE DB: Positron emission tomographic evidence for progression of human MPTP-induced dopaminergic lesions. Ann. Neurol. (1994) 36:765-770.
-
(1994)
Ann. Neurol
, vol.36
, pp. 765-770
-
-
Vingerhoets, F.J.1
Snow, B.J.2
Tetrud, J.W.3
Langston, J.W.4
Schulzer, M.5
Calne, D.B.6
-
336
-
-
0028875565
-
Neurological sequelae of cyanide intoxication - The patterns of clinical, magnetic resonance imaging, and positron emission tomography findings
-
ROSENOW F, HERHOLZ K, LANFERMANN H et al.: Neurological sequelae of cyanide intoxication - the patterns of clinical, magnetic resonance imaging, and positron emission tomography findings. Ann. Neurol. (1995) 38:825-828.
-
(1995)
Ann. Neurol
, vol.38
, pp. 825-828
-
-
Rosenow, F.1
Herholz, K.2
Lanfermann, H.3
-
337
-
-
0027249375
-
Progression after chronic manganese exposure
-
HUANG CC, LU CS, CHU NS et al.: Progression after chronic manganese exposure. Neurology (1993) 43:1479-1483.
-
(1993)
Neurology
, vol.43
, pp. 1479-1483
-
-
Huang, C.C.1
Lu, C.S.2
Chu, N.S.3
-
338
-
-
0033913011
-
Traumatic brain injury as a risk factor for Alzheimer's disease: A review
-
LYE TC, SHORES EA: Traumatic brain injury as a risk factor for Alzheimer's disease: a review. Neuropsychol. Rev. (2000) 10:115-129.
-
(2000)
Neuropsychol. Rev
, vol.10
, pp. 115-129
-
-
Lye, T.C.1
Shores, E.A.2
-
339
-
-
0034644203
-
A one-hit model of cell death in inherited neuronal degenerations
-
CLARKE G, COLLINS RA, LEAVITT BR et al.: A one-hit model of cell death in inherited neuronal degenerations. Nature (2000) 406:195-199.
-
(2000)
Nature
, vol.406
, pp. 195-199
-
-
Clarke, G.1
Collins, R.A.2
Leavitt, B.R.3
-
340
-
-
0035473963
-
Inherited neurodegenerative diseases: The one-hit model of neurodegeneration
-
CLARKE G, LUMSDEN CJ, MCINNES RR: Inherited neurodegenerative diseases: the one-hit model of neurodegeneration. Hum. Mol. Genet. (2001) 10:2269-2275.
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 2269-2275
-
-
Clarke, G.1
Lumsden, C.J.2
Mcinnes, R.R.3
-
341
-
-
0029027838
-
Electrophile and antioxidant regulation of enzymes that detoxify carcinogens
-
PRESTERA T, TALALAY P: Electrophile and antioxidant regulation of enzymes that detoxify carcinogens. Proc. Natl. Acad. Sci. USA (1995) 92:8965-8969.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8965-8969
-
-
Prestera, T.1
Talalay, P.2
-
342
-
-
0027487416
-
The electrophile counterattack response: Protection against neoplasia and toxicity
-
PRESTERA T, ZHANG Y, SPENCER SR, WILCZAK CA, TALALAY P: The electrophile counterattack response: protection against neoplasia and toxicity. Adv. Enzyme Regul. (1993) 33:281-296.
-
(1993)
Adv. Enzyme Regul
, vol.33
, pp. 281-296
-
-
Prestera, T.1
Zhang, Y.2
Spencer, S.R.3
Wilczak, C.A.4
Talalay, P.5
-
343
-
-
33748218712
-
Misconceptions on pollution and the causes of cancer
-
AMES BN, GOLD LS: Misconceptions on pollution and the causes of cancer. Angew. Chem. Int. Ed. (1990) 29:1197-1208.
-
(1990)
Angew. Chem. Int. Ed
, vol.29
, pp. 1197-1208
-
-
Ames, B.N.1
Gold, L.S.2
-
344
-
-
0031830786
-
What do animal cancer tests tell us about human cancer risk? Overview of analyses of the carcinogenic potency database
-
GOLD LS, SLONE TH, AMES BN: What do animal cancer tests tell us about human cancer risk? Overview of analyses of the carcinogenic potency database. Drug Metab. Rev. (1998) 30:359-404.
-
(1998)
Drug Metab. Rev
, vol.30
, pp. 359-404
-
-
Gold, L.S.1
Slone, T.H.2
Ames, B.N.3
-
345
-
-
0033533414
-
Compounds that induce isoforms of glutathione S-transferase with properties of a critical enzyme in defense against oxidative stress
-
FIANDER H, SCHNEIDER H: Compounds that induce isoforms of glutathione S-transferase with properties of a critical enzyme in defense against oxidative stress. Biochem. Biopbys. Res. Commun. (1999) 262:591-595.
-
(1999)
Biochem. Biopbys. Res. Commun
, vol.262
, pp. 591-595
-
-
Fiander, H.1
Schneider, H.2
-
346
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
ESTERBAUER H, SCHAUR RJ, ZOLLNER H: Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic. Biol. Med. (1991) 11:81-128.
-
(1991)
Free Radic. Biol. Med
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
347
-
-
0030989545
-
4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
-
SAYRE LM, ZELASKO DA, HARRIS PL, PERRY G, SALOMON RG, SMITH MA: 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. (1997) 68:2092-2097.
-
(1997)
J Neurochem
, vol.68
, pp. 2092-2097
-
-
Sayre, L.M.1
Zelasko, D.A.2
Harris, P.L.3
Perry, G.4
Salomon, R.G.5
Smith, M.A.6
-
348
-
-
0032905632
-
Protein-bound acrolein: A novel marker of oxidative stress in Alzheimer's disease
-
CALINGASAN NY, UCHIDA K, GIBSON GE: Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease. J Neurochem. (1999) 72:751-756.
-
(1999)
J. Neurochem
, vol.72
, pp. 751-756
-
-
Calingasan, N.Y.1
Uchida, K.2
Gibson, G.E.3
-
349
-
-
0029073455
-
Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's diesease
-
LOVELL MA, EHMANN WD, BUTLER SM, MARKESBERY WR. Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's diesease. Neurology (1995) 45:1594-1601.
-
(1995)
Neurology
, vol.45
, pp. 1594-1601
-
-
Lovell, M.A.1
Ehmann, W.D.2
Butler, S.M.3
Markesbery, W.R.4
-
350
-
-
0028023944
-
Glycated tau protein in Alzheimer's disease: A mechanism for induction of oxidant stress
-
YAN SD, CHEN X, SCHMIDT AM et al.: Glycated tau protein in Alzheimer's disease: a mechanism for induction of oxidant stress. Proc. Natl. Acad. Sci. USA (1994) 91:7787-7791.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7787-7791
-
-
Yan, S.D.1
Chen, X.2
Schmidt, A.M.3
-
351
-
-
0033836580
-
Alzheimer's disease, heme oxygenase is coincident with Alz5O, an epitope of tau induced by 4-hydroxy-2-nonenal modification
-
TAKEDA A, SMITH MA, AVILA J et al.: In Alzheimer's disease, heme oxygenase is coincident with Alz5O, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J. Neurochem. (2000) 75:1234-1241.
-
(2000)
J. Neurochem
, vol.75
, pp. 1234-1241
-
-
Takeda, A.1
Smith, M.A.2
Avila, J.3
-
352
-
-
0041721771
-
Transition metal-mediated glycoxidation accelerates cross-linking of amyloid peptide
-
LOSKE C, GERDEMANN A, SCHEPL W et al.: Transition metal-mediated glycoxidation accelerates cross-linking of amyloid peptide. Eur. J. Biochem. (2000) 267:4171-4178.
-
(2000)
Eur. J. Biochem
, vol.267
, pp. 4171-4178
-
-
Loske, C.1
Gerdemann, A.2
Schepl, W.3
-
353
-
-
0030986669
-
Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
-
KRUMAN I, BRUCE-KELLER AJ, BREDESEN D, WAEG G, MATTSON MP: Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J. Neurosci. (1997) 17:5089-5100.
-
(1997)
J. Neurosci
, vol.17
, pp. 5089-5100
-
-
Kruman, I.1
Bruce-Keller, A.J.2
Bredesen, D.3
Waeg, G.4
Mattson, M.P.5
-
354
-
-
0032533744
-
Glutathione transferase protects neuronal cultures against 4-hydroxynonenal toxicity
-
XIE C, LOVELL MA, MARKESBERY WR: Glutathione transferase protects neuronal cultures against 4-hydroxynonenal toxicity. Free Radic. Biol. Med. (1998) 25:979-988.
-
(1998)
Free Radic. Biol. Med
, vol.25
, pp. 979-988
-
-
Xie, C.1
Lovell, M.A.2
Markesbery, W.R.3
-
355
-
-
0035909947
-
Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of sulforaphane
-
GAO X, DINKOVA-KOSTOVA AT, TALALAY P: Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane. Proc. Natl. Acad. Sci. USA (2001) 98:15221-15226.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 15221-15226
-
-
Gao, X.1
Dinkova-kostova, A.T.2
Talalay, P.3
-
356
-
-
0034637704
-
Dietary ortho-phenols that induce glutathione S-transferase and increase the resistance of cells to hydrogen peroxide are potential cancer chemopreventives that act by two mechanisms: The alleviation of oxidative stress and the detoxification of mutagenic xenobiotics
-
FIANDER H, SCHNEIDER H: Dietary ortho-phenols that induce glutathione S-transferase and increase the resistance of cells to hydrogen peroxide are potential cancer chemopreventives that act by two mechanisms: the alleviation of oxidative stress and the detoxification of mutagenic xenobiotics. Cancer Lett. (2000) 156:117-124.
-
(2000)
Cancer Lett
, vol.156
, pp. 117-124
-
-
Fiander, H.1
Schneider, H.2
-
357
-
-
0032519517
-
Human glutathione transferase A4-4: An alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation
-
HUBATSCH I, RIDDERSTROM M, MANNERVIK B: Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation. Biochem. J. (1998) 330:175-179.
-
(1998)
Biochem. J
, vol.330
, pp. 175-179
-
-
Hubatsch, I.1
Ridderstrom, M.2
Mannervik, B.3
-
358
-
-
0033739282
-
Apoptosis and Alzheimer's disease
-
BEHL C: Apoptosis and Alzheimer's disease. J. Neural Transm. (2000) 107:1325-1344.
-
(2000)
J. Neural Transm
, vol.107
, pp. 1325-1344
-
-
Behl, C.1
-
359
-
-
0034329742
-
Apoptosis in neurodegenerative disorders
-
MATTSON M: Apoptosis in neurodegenerative disorders. Nat. Rev. Mol. Cell Biol. (2000) 1:120-129.
-
(2000)
Nat. Rev. Mol. Cell Biol
, vol.1
, pp. 120-129
-
-
Mattson, M.1
-
360
-
-
0035027964
-
Abortive apoptosis in Alzheimer's disease
-
RAINA AK, HOCHMAN A, ZHU X et al.: Abortive apoptosis in Alzheimer's disease. Acta Neuropathol. (2001) 101:305-310.
-
(2001)
Acta Neuropathol
, vol.101
, pp. 305-310
-
-
Raina, A.K.1
Hochman, A.2
Zhu, X.3
-
361
-
-
0035865819
-
Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms
-
ISHIGE K, SCHUBERT D, SAGARA Y: Flavonoids protect neuronal cells from oxidative stress by three distinct mechanisms. Free Radic. Biol, Med. (2001) 30:433-446.
-
(2001)
Free Radic. Biol. Med
, vol.30
, pp. 433-446
-
-
Ishige, K.1
Schubert, D.2
Sagara, Y.3
-
362
-
-
0035489192
-
Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin
-
CHOI JA, KIM JY, LEE JY et al.: Induction of cell cycle arrest and apoptosis in human breast cancer cells by quercetin. Int. Oncol. (2001) 19:837-844.
-
(2001)
Int. Oncol
, vol.19
, pp. 837-844
-
-
Choi, J.A.1
Kim, J.Y.2
Lee, J.Y.3
-
363
-
-
0034660863
-
Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells
-
WENZEL U, KUNTZ S, BRENDEL MD, DANIEL H: Dietary flavone is a potent apoptosis inducer in human colon carcinoma cells. Cancer Res. (2000) 60:3823-3831.
-
(2000)
Cancer Res
, vol.60
, pp. 3823-3831
-
-
Wenzel, U.1
Kuntz, S.2
Brendel, M.D.3
Daniel, H.4
-
364
-
-
0034813095
-
Neuronal apoptosis resulting from high doses of the isoflavone genistein: role for calcium and p42/44 mitogen-activated protein kinase
-
LINFORD NJ, YANG Y, COOK DG, DORSA DM: Neuronal apoptosis resulting from high doses of the isoflavone genistein: role for calcium and p42/44 mitogen-activated protein kinase. J. Pharmacol. Exp. Ther. (2001) 299:67-75.
-
(2001)
J. Pharmacol. Exp. Ther
, vol.299
, pp. 67-75
-
-
Linford, N.J.1
Yang, Y.2
Cook, D.G.3
Dorsa, D.M.4
-
365
-
-
0034519306
-
Cancer chemoprevention and apoptosis mechanisms induced by dietary polyphenolics
-
GALATI G, TENG S, MORIDANI MY, CHAN TS, O'BRIEN PJ: Cancer chemoprevention and apoptosis mechanisms induced by dietary polyphenolics. Drug Metab. Drug Interact. (2000) 17:311-349.
-
(2000)
Drug Metab. Drug Interact
, vol.17
, pp. 311-349
-
-
Galati, G.1
Teng, S.2
Moridani, M.Y.3
Chan, T.S.4
O'Brien, P.J.5
-
366
-
-
0032826055
-
Redox regulation of c-Jun DNA binding by reversible S-glutathiolation
-
KLATT P, MOLINA EP, DE LACOBA MG et al.: Redox regulation of c-Jun DNA binding by reversible S-glutathiolation. FASEB J. (1999) 13:1481-1490.
-
(1999)
FASEB J
, vol.13
, pp. 1481-1490
-
-
Klatt, P.1
Molina, E.P.2
De Lacoba, M.G.3
-
367
-
-
0032488513
-
Recent trends in glutathione biochemistry-glutathione-protein interactions: A molecular link between oxidative stress and cell proliferation?
-
COTGREAVE IA, GERDES RG: Recent trends in glutathione biochemistry-glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? Biochem. Biophys. Res. Commun. (1998) 242:1-9.
-
(1998)
Biochem. Biophys. Res. Commun
, vol.242
, pp. 1-9
-
-
Cotgreave, I.A.1
Gerdes, R.G.2
-
368
-
-
0028075410
-
Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
-
SIAN J, DEXTER DT LEES AJ et al.: Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. (1994) 36:348-355.
-
(1994)
Ann. Neurol
, vol.36
, pp. 348-355
-
-
Sian, J.1
Dexter, D.T.2
Lees, A.J.3
-
370
-
-
0025299455
-
L-cysteine, a bicarbonate-sensitive endogenous excitotoxin
-
OLNEY JW, ZORUMSKI C, PRICE MT, LABRUYERE J: L-cysteine, a bicarbonate-sensitive endogenous excitotoxin. Science (1990) 248:596-599.
-
(1990)
Science
, vol.248
, pp. 596-599
-
-
Olney, J.W.1
Zorumski, C.2
Price, M.T.3
Labruyere, J.4
-
371
-
-
0034655266
-
Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of L-cysteine
-
YEH MW, KAUL M, ZHENG J et al.: Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of L-cysteine. J. Immunol. (2000) 164:4265-4270.
-
(2000)
J. Immunol
, vol.164
, pp. 4265-4270
-
-
Yeh, M.W.1
Kaul, M.2
Zheng, J.3
-
372
-
-
0036172871
-
Safety and efficacy of idebenone versus tacrine in patients with Alzheimer's disease: Results of a randomized, double-blind, parallel-group multicenter study
-
GUTZMANN H, KUHL KP, HADLER D, RAPP MA: Safety and efficacy of idebenone versus tacrine in patients with Alzheimer's disease: results of a randomized, double-blind, parallel-group multicenter study. Pharmacopsychiatry (2002) 35:12-18.
-
(2002)
Pharmacopsychiatry
, vol.35
, pp. 12-18
-
-
Gutzmann, H.1
Kuhl, K.P.2
Hadler, D.3
Rapp, M.A.4
-
373
-
-
0036231440
-
Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: A randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial
-
SHOULSON I, OAKES D, FAHN S et al.: Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial. Ann. Neurol. (2002) 51:604-612.
-
(2002)
Ann. Neurol
, vol.51
, pp. 604-612
-
-
Shoulson, I.1
Oakes, D.2
Fahn, S.3
|