Modeling Alzheimer's disease in transgenic mice: Effect of age and of Presenilin1 on amyloid biochemistry and pathology in APP/London mice

Experimental Gerontology

Volumn 35, Issue 6-7, 2000, Pages 831-841

  Dewachter, I ^a   Van Dorpe, J ^a   Spittaels, K ^a   Tesseur, I ^a   Van Den Haute, C ^a   Moechars, D ^a   Van Leuven, F ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Age and Presenilin1; Modeling Alzheimer's disease; Transgenic mice

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AMYLOID PROTEIN; APOLIPOPROTEIN E4; BETA SECRETASE; GLUTAMIC ACID; PRESENILIN 1; TAU PROTEIN;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; MOTONEURON; MOUSE; MUSCLE ATROPHY; NERVE DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROPATHY; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; SYMPTOMATOLOGY; TRANSGENIC MOUSE; VASCULAR AMYLOIDOSIS;

AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMAL; APOLIPOPROTEINS E; DISEASE MODELS, ANIMAL; HUMAN; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; SUPPORT, NON-U.S. GOV'T; TAU PROTEINS;

ANIMALIA; MUS MUSCULUS; SIGANUS;

EID: 0033784099     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(00)00149-2     Document Type: Conference Paper

References (19)

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