Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

Synapse

Volumn 39, Issue 2, 2001, Pages 167-174

  Teismann, Peter ^a   Ferger, Boris ^a,b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b ETH ZURICH   (Switzerland)

Author keywords

Acetylsalicylic acid; Inflammation; Meloxicam; Neurodegeneration; Substantia nigra

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 3,4 DIHYDROXYPHENYLACETIC ACID; ACETYLSALICYLIC ACID; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; MELOXICAM; PROSTAGLANDIN SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; IMMUNOREACTIVITY; LOCOMOTION; MALE; MICROSCOPIC ANATOMY; MOUSE; NEUROCHEMISTRY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL;

1-METHYL-4-PHENYLPYRIDINIUM; 3,4-DIHYDROXYPHENYLACETIC ACID; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; CELL COUNT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DISEASE MODELS, ANIMAL; DOPAMINE; HOMOVANILLIC ACID; ISOENZYMES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NEOSTRIATUM; NEUROPROTECTIVE AGENTS; PARKINSONIAN DISORDERS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SUBSTANTIA NIGRA; THIAZINES; THIAZOLES; TYROSINE 3-MONOOXYGENASE;

EID: 0035134830     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/1098-2396(200102)39:2<167::AID-SYN8>3.0.CO;2-U     Document Type: Article

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