Interference by huntingtin and atrophin-1 with CBP-mediated transcription leading to cellular toxicity

Science

Volumn 291, Issue 5512, 2001, Pages 2423-2428

  Nucifora F C , Jr ^a   Sasaki, M ^a   Peters, M F ^a   Huang, H ^a   Cooper, J K ^a   Yamada, M ^a   Takahashi, H ^a   Tsuji, S ^a   Troncoso, J ^a   Dawson, V L ^a   Dawson, T M ^a   Ross, C A ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HUNTINGTIN; POLYGLUTAMINE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MOUSE; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL;

ANIMALS; BRAIN; CELL NUCLEUS; CELL SURVIVAL; CELLS, CULTURED; CREB-BINDING PROTEIN; HUMANS; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PEPTIDES; REPETITIVE SEQUENCES, AMINO ACID; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS;

EID: 0035937523     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1056784     Document Type: Article

References (49)