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Volumn 54, Issue 2, 2000, Pages 295-301

Estrogen for Alzheimer's disease in women: Randomized, double-blind, placebo-controlled trial

Author keywords

AD; Clinical trial; Cognition; Estrogen; Mood Women

Indexed keywords

CONJUGATED ESTROGEN; PLACEBO;

EID: 0034711656     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.54.2.295     Document Type: Article
Times cited : (533)

References (45)
  • 1
    • 0025221468 scopus 로고
    • Estimated prevalence of Alzheimer's disease in the United States
    • Evans DA, Scherr PA, Cook NR, et al. Estimated prevalence of Alzheimer's disease in the United States. Milbank Quart 1990;68:267-289.
    • (1990) Milbank Quart , vol.68 , pp. 267-289
    • Evans, D.A.1    Scherr, P.A.2    Cook, N.R.3
  • 2
    • 0031695197 scopus 로고    scopus 로고
    • Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset
    • Brookmeyer R, Gray S, Kawas C. Projections of Alzheimer's disease in the United States and the public health impact of delaying disease onset. Am J Public Health 1998;88:1337-1342.
    • (1998) Am J Public Health , vol.88 , pp. 1337-1342
    • Brookmeyer, R.1    Gray, S.2    Kawas, C.3
  • 3
    • 0028086440 scopus 로고
    • Estrogen replacement therapy in older women: Comparisons between Alzheimer's disease cases and non-demented control subjects
    • Henderson VW, Paganini-Hill A, Emanuel CK, Dunn ME, Buckwalter JG. Estrogen replacement therapy in older women: comparisons between Alzheimer's disease cases and non-demented control subjects. Arch Neurol 1994;51:896-900.
    • (1994) Arch Neurol , vol.51 , pp. 896-900
    • Henderson, V.W.1    Paganini-Hill, A.2    Emanuel, C.K.3    Dunn, M.E.4    Buckwalter, J.G.5
  • 4
    • 0029844969 scopus 로고    scopus 로고
    • Estrogen replacement therapy and risk of Alzheimer's disease
    • Paganini-Hill A, Henderson VW. Estrogen replacement therapy and risk of Alzheimer's disease. Arch Intern Med 1996; 156:2213-2217.
    • (1996) Arch Intern Med , vol.156 , pp. 2213-2217
    • Paganini-Hill, A.1    Henderson, V.W.2
  • 5
    • 0030591669 scopus 로고    scopus 로고
    • Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
    • Tang M-X, Jacobs D, Stern Y, et al. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 1996;348:429-432.
    • (1996) Lancet , vol.348 , pp. 429-432
    • Tang, M.-X.1    Jacobs, D.2    Stern, Y.3
  • 6
    • 0030748719 scopus 로고    scopus 로고
    • A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
    • Kawas C, Resnick S, Morrison A, et al. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: the Baltimore Longitudinal Study of Aging. Neurology 1997;48:1517-1521.
    • (1997) Neurology , vol.48 , pp. 1517-1521
    • Kawas, C.1    Resnick, S.2    Morrison, A.3
  • 7
    • 0031899264 scopus 로고    scopus 로고
    • Estrogen-replacement therapy and Alzheimer's disease in the Italian Longitudinal Study on Aging
    • Baldereschi M, Di Carlo A, Lepore V, et al. Estrogen-replacement therapy and Alzheimer's disease in the Italian Longitudinal Study on Aging. Neurology 1998;50:996-1002.
    • (1998) Neurology , vol.50 , pp. 996-1002
    • Baldereschi, M.1    Di Carlo, A.2    Lepore, V.3
  • 9
    • 0030152121 scopus 로고    scopus 로고
    • Cognitive skills associated with estrogen replacement in women with Alzheimer's disease
    • Henderson VW, Watt L, Buckwalter JG. Cognitive skills associated with estrogen replacement in women with Alzheimer's disease. Psychoneuroendocrinology 1996;21:421-430.
    • (1996) Psychoneuroendocrinology , vol.21 , pp. 421-430
    • Henderson, V.W.1    Watt, L.2    Buckwalter, J.G.3
  • 10
    • 0030837745 scopus 로고    scopus 로고
    • The Alzheimer's disease assessment scale: Patterns and predictors of baseline cognitive performance in multicenter Alzheimer's disease trials
    • Doraiswamy PM, Bieber F, Kaiser L, Krishnan KR, Reuning-Scherer J, Gulanski B. The Alzheimer's disease assessment scale: patterns and predictors of baseline cognitive performance in multicenter Alzheimer's disease trials. Neurology 1997;48:1511-1517.
    • (1997) Neurology , vol.48 , pp. 1511-1517
    • Doraiswamy, P.M.1    Bieber, F.2    Kaiser, L.3    Krishnan, K.R.4    Reuning-Scherer, J.5    Gulanski, B.6
  • 11
    • 0030775962 scopus 로고    scopus 로고
    • Estrogen replacement therapy for the prevention and treatment of Alzheimer's disease
    • Henderson VW. Estrogen replacement therapy for the prevention and treatment of Alzheimer's disease. CNS Drugs 1997;8: 343-351.
    • (1997) CNS Drugs , vol.8 , pp. 343-351
    • Henderson, V.W.1
  • 13
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein MF, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.F.3    Katzman, R.4    Price, D.5    Stadlan, E.M.6
  • 14
    • 0028931819 scopus 로고
    • Exogenous androgens in postmenopausal women
    • Sands R, Studd J. Exogenous androgens in postmenopausal women. Am J Med 1995;98(suppl 1A):76S-79S.
    • (1995) Am J Med , vol.98 , Issue.SUPPL. 1A
    • Sands, R.1    Studd, J.2
  • 15
    • 0029886801 scopus 로고    scopus 로고
    • Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease
    • Schneider LS, Farlow MR, Henderson VW, Pogoda JM. Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease. Neurology 1996;46: 1580-1584.
    • (1996) Neurology , vol.46 , pp. 1580-1584
    • Schneider, L.S.1    Farlow, M.R.2    Henderson, V.W.3    Pogoda, J.M.4
  • 16
    • 0028969073 scopus 로고
    • Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports
    • Ohkura T, Isse K, Akazawa K, Hamamoto M, Yaoi Y, Hagino N. Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports. Dementia 1995;6:99-107.
    • (1995) Dementia , vol.6 , pp. 99-107
    • Ohkura, T.1    Isse, K.2    Akazawa, K.3    Hamamoto, M.4    Yaoi, Y.5    Hagino, N.6
  • 17
    • 0028291648 scopus 로고
    • Differences in pharmacokinetics and comparative bioavailability between Premarin and Estratab in healthy post-menopausal women
    • Troy SM, Hicks DR, Parker VD, Jusko WJ, Rofsky HE, Porter RJ. Differences in pharmacokinetics and comparative bioavailability between Premarin and Estratab in healthy post-menopausal women. Curr Ther Res 1994;55:359-372.
    • (1994) Curr Ther Res , vol.55 , pp. 359-372
    • Troy, S.M.1    Hicks, D.R.2    Parker, V.D.3    Jusko, W.J.4    Rofsky, H.E.5    Porter, R.J.6
  • 18
    • 0019906926 scopus 로고
    • Comparison of pharmacodynamic properties of various estrogen preparations
    • Mashchak CA, Lobo RA, Dozono-Takano R, et al. Comparison of pharmacodynamic properties of various estrogen preparations. Am J Obstet Gynecol 1982;144:511-518.
    • (1982) Am J Obstet Gynecol , vol.144 , pp. 511-518
    • Mashchak, C.A.1    Lobo, R.A.2    Dozono-Takano, R.3
  • 19
    • 0018184826 scopus 로고
    • Allocation of patients to treatment groups in a controlled clinical study
    • White SJ, Freedman LS. Allocation of patients to treatment groups in a controlled clinical study. Br J Cancer 1978;37: 849-857.
    • (1978) Br J Cancer , vol.37 , pp. 849-857
    • White, S.J.1    Freedman, L.S.2
  • 20
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry 1984;141:1356-1364.
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2    Davis, K.L.3
  • 21
    • 0024273881 scopus 로고
    • Clinical predictors of course for Alzheimer's patients in a longitudinal study: A preliminary report
    • Kramer-Ginsberg E, Mohs RC, Aryan M, et al. Clinical predictors of course for Alzheimer's patients in a longitudinal study: a preliminary report. Psychopharmacol Bull 1988;24:458-462.
    • (1988) Psychopharmacol Bull , vol.24 , pp. 458-462
    • Kramer-Ginsberg, E.1    Mohs, R.C.2    Aryan, M.3
  • 22
    • 0028262405 scopus 로고
    • A longitudinal study of Alzheimer's disease: Measurement, rate, and predictors of cognitive deterioration
    • Stern RG, Mohs RC, Davidson M, et al. A longitudinal study of Alzheimer's disease: measurement, rate, and predictors of cognitive deterioration. Am J Psychiatry 1994;151:390-396.
    • (1994) Am J Psychiatry , vol.151 , pp. 390-396
    • Stern, R.G.1    Mohs, R.C.2    Davidson, M.3
  • 23
    • 0030862602 scopus 로고    scopus 로고
    • Validity and reliability of the Alzheimer's Disease Study - Global Impression of Change
    • Schneider LS, Olin JT, Doody RS, et al. Validity and reliability of the Alzheimer's Disease Study - Global Impression of Change. Alzheimer Dis Assoc Disord 1997;11(suppl 2):S22-S32.
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , Issue.2 SUPPL.
    • Schneider, L.S.1    Olin, J.T.2    Doody, R.S.3
  • 24
    • 0014579432 scopus 로고
    • Assessment of older people: Self-maintaining and instrumental activities of daily living
    • Lawton MP, Brody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 1969;9:179-186.
    • (1969) Gerontologist , vol.9 , pp. 179-186
    • Lawton, M.P.1    Brody, E.M.2
  • 25
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, Asberg MA. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382-389.
    • (1979) Br J Psychiatry , vol.134 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.A.2
  • 26
    • 0000490053 scopus 로고
    • Collateral source Geriatric Depression Scale
    • Nitcher RL. Collateral source Geriatric Depression Scale. Am J Geriatr Psychiatry 1993;1:143-152.
    • (1993) Am J Geriatr Psychiatry , vol.1 , pp. 143-152
    • Nitcher, R.L.1
  • 28
    • 0030727813 scopus 로고    scopus 로고
    • Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system
    • Shughrue PJ, Lane MV, Merchenthaler I. Comparative distribution of estrogen receptor-α and -β mRNA in the rat central nervous system. J Comp Neurol 1997;388:507-525.
    • (1997) J Comp Neurol , vol.388 , pp. 507-525
    • Shughrue, P.J.1    Lane, M.V.2    Merchenthaler, I.3
  • 29
    • 0030453131 scopus 로고    scopus 로고
    • Nongenomic actions of estrogen in the brain: Physiological significance and cellular mechanisms
    • Wong M, Thompson TL, Moss RL. Nongenomic actions of estrogen in the brain: physiological significance and cellular mechanisms. Crit Rev Neurobiol 1996;10:189-203.
    • (1996) Crit Rev Neurobiol , vol.10 , pp. 189-203
    • Wong, M.1    Thompson, T.L.2    Moss, R.L.3
  • 30
    • 0030818060 scopus 로고    scopus 로고
    • Estrogen, cognition, and a woman's risk of Alzheimer's disease
    • Henderson VW. Estrogen, cognition, and a woman's risk of Alzheimer's disease. Am J Med 1997;103(suppl 3A):11-18.
    • (1997) Am J Med , vol.103 , Issue.SUPPL. 3A , pp. 11-18
    • Henderson, V.W.1
  • 31
    • 0031946864 scopus 로고    scopus 로고
    • Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
    • Xu H, Gouras GK, Greenfield JP, et al. Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides. Nat Med 1998;4:447-451.
    • (1998) Nat Med , vol.4 , pp. 447-451
    • Xu, H.1    Gouras, G.K.2    Greenfield, J.P.3
  • 32
    • 0032080001 scopus 로고    scopus 로고
    • Increased synaptic spouting in response to estrogen via an apolipoprotein E dependent mechanism: Implications for Alzheimer's disease
    • Stone DJ, Rozovsky I, Morgan TE, Anderson CP, Finch CE. Increased synaptic spouting in response to estrogen via an apolipoprotein E dependent mechanism: implications for Alzheimer's disease. J Neurosci 1998;18:3180-3185.
    • (1998) J Neurosci , vol.18 , pp. 3180-3185
    • Stone, D.J.1    Rozovsky, I.2    Morgan, T.E.3    Anderson, C.P.4    Finch, C.E.5
  • 33
    • 0032997908 scopus 로고    scopus 로고
    • L expression and β-amyloid-induced apoptosis: Relevance to Alzheimer's disease
    • L expression and β-amyloid-induced apoptosis: relevance to Alzheimer's disease. J Neurochem 1999;72:1552-1563.
    • (1999) J Neurochem , vol.72 , pp. 1552-1563
    • Pike, C.J.1
  • 34
    • 0000512693 scopus 로고
    • An effect of conjugated estrogen to cognitive impairment in women with senile dementia - Alzheimer's type: A placebo-controlled double blind study
    • Honjo H, Ogino Y, Tanaka K, et al. An effect of conjugated estrogen to cognitive impairment in women with senile dementia - Alzheimer's type: a placebo-controlled double blind study. J Jpn Menopause Soc 1993;1:167-171.
    • (1993) J Jpn Menopause Soc , vol.1 , pp. 167-171
    • Honjo, H.1    Ogino, Y.2    Tanaka, K.3
  • 35
    • 0028578027 scopus 로고
    • Estrogens in the pathogenesis and treatment of Alzheimer's disease in postmenopausal women
    • Fillit H. Estrogens in the pathogenesis and treatment of Alzheimer's disease in postmenopausal women. Ann NY Acad Sci 1994;743:233-238.
    • (1994) Ann NY Acad Sci , vol.743 , pp. 233-238
    • Fillit, H.1
  • 36
    • 0033003028 scopus 로고    scopus 로고
    • Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: Results of a placebo-controlled, double-blind, pilot study
    • Asthana S, Craft S, Baker LD, et al. Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: results of a placebo-controlled, double-blind, pilot study. Psychoneuroendocrinology 1999;24:657-677.
    • (1999) Psychoneuroendocrinology , vol.24 , pp. 657-677
    • Asthana, S.1    Craft, S.2    Baker, L.D.3
  • 37
    • 0030942683 scopus 로고    scopus 로고
    • The role of estrogen in the treatment of Alzheimer's disease
    • Birge SJ. The role of estrogen in the treatment of Alzheimer's disease. Neurology 1997;48(suppl 7):S36-S41.
    • (1997) Neurology , vol.48 , Issue.7 SUPPL.
    • Birge, S.J.1
  • 38
    • 0028270519 scopus 로고
    • A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
    • Knapp MJ, Knopman DS, Solomon PR, Pendlebury WW, Davis CS, Garcon SI. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA 1994;271:985-991.
    • (1994) JAMA , vol.271 , pp. 985-991
    • Knapp, M.J.1    Knopman, D.S.2    Solomon, P.R.3    Pendlebury, W.W.4    Davis, C.S.5    Garcon, S.I.6
  • 39
    • 0031883716 scopus 로고    scopus 로고
    • A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
    • Rogers SL, Farlow MR, Doody RS, Mohs R, Friedhoff LT. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology 1998;50:136-145.
    • (1998) Neurology , vol.50 , pp. 136-145
    • Rogers, S.L.1    Farlow, M.R.2    Doody, R.S.3    Mohs, R.4    Friedhoff, L.T.5
  • 40
    • 0033528436 scopus 로고    scopus 로고
    • Efficacy and safety of rivastigmine in patients with Alzheimer's disease: International randomised controlled trial
    • Rösler M, Anand R, Cicin-Sain A, et al. Efficacy and safety of rivastigmine in patients with Alzheimer's disease: international randomised controlled trial. BMJ 1999;318:633-640.
    • (1999) BMJ , vol.318 , pp. 633-640
    • Rösler, M.1    Anand, R.2    Cicin-Sain, A.3
  • 41
    • 0027102043 scopus 로고
    • Effects of estrogen on memory function in surgically menopausal women
    • Phillips SM, Sherwin BB. Effects of estrogen on memory function in surgically menopausal women. Psychoneuroendocrinology 1992;17:485-495.
    • (1992) Psychoneuroendocrinology , vol.17 , pp. 485-495
    • Phillips, S.M.1    Sherwin, B.B.2
  • 42
    • 0029900525 scopus 로고    scopus 로고
    • "Add-back" estrogen reverses cognitive deficits induced by a gonadotropin-releasing hormone agonist in women with leiomyomata uteri
    • Sherwin BB, Tulandi T. "Add-back" estrogen reverses cognitive deficits induced by a gonadotropin-releasing hormone agonist in women with leiomyomata uteri. J Clin Endocrinol Metab 1996;81:2545-2549.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 2545-2549
    • Sherwin, B.B.1    Tulandi, T.2
  • 43
    • 0041927165 scopus 로고    scopus 로고
    • Interaction of estrogen replacement therapy and apolipoprotein genotype status on response to cholinesterase inhibitor therapy in Alzheimer's disease
    • Iqbal K, Binblad B, Nishimura T, Takeda M, Wisniewski HM, eds. New York: John Wiley & Sons
    • Schneider LS, Farlow MR, Pogoda JM, Poirier J. Interaction of estrogen replacement therapy and apolipoprotein genotype status on response to cholinesterase inhibitor therapy in Alzheimer's disease. In: Iqbal K, Binblad B, Nishimura T, Takeda M, Wisniewski HM, eds. Alzheimer's disease: biology, diagnosis and therapeutics. New York: John Wiley & Sons, 1997: 657-661.
    • (1997) Alzheimer's Disease: Biology, Diagnosis and Therapeutics , pp. 657-661
    • Schneider, L.S.1    Farlow, M.R.2    Pogoda, J.M.3    Poirier, J.4
  • 44
    • 0016823810 scopus 로고
    • "Mini-mental state." a practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 45
    • 0018887732 scopus 로고
    • Pathological verification of ischemic score in differentiation of dementias
    • Rosen WG, Terry RD, Fuld PA, Katzman R, Peck A. Pathological verification of ischemic score in differentiation of dementias. Ann Neurol 1980;7:486-488.
    • (1980) Ann Neurol , vol.7 , pp. 486-488
    • Rosen, W.G.1    Terry, R.D.2    Fuld, P.A.3    Katzman, R.4    Peck, A.5


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