Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis

Journal of Neuroscience

Volumn 17, Issue 13, 1997, Pages 5089-5100

  Kruman, Inna ^a   Bruce Keller, Annadora J ^a   Bredesen, Dale ^b   Waeg, Georg ^c   Mattson, Mark P ^a,d  

^a UNIVERSITY OF KENTUCKY   (United States)

^b BURNHAM INSTITUTE   (United States)

^c UNIVERSITY OF GRAZ   (Austria)

^d UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; Amyloid peptide; Bcl 2; Glutathione; Hippocampal neurons; Iron; Lipid peroxidation; Mitochondria; Programmed cell death; Reactive oxygen species; Vitamin E

Indexed keywords

DNA FRAGMENT; EXCITOTOXIN; GLUTATHIONE; REACTIVE OXYGEN METABOLITE;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CELL STRAIN; DEGENERATIVE DISEASE; DETOXIFICATION; ENZYME ACTIVITY; LIPID PEROXIDATION; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL;

EID: 0030986669     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-13-05089.1997     Document Type: Article

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