메뉴 건너뛰기




Volumn 41, Issue 2, 1997, Pages 160-165

Energy metabolism defects in Huntington's disease and effects of coenzyme Q10

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE PHOSPHATE; LACTIC ACID; PHOSPHATE; PYRUVIC ACID; UBIQUINONE;

EID: 0031044805     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.410410206     Document Type: Article
Times cited : (382)

References (35)
  • 1
    • 0027480960 scopus 로고
    • The novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group. The novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-983
    • (1993) Cell , vol.72 , pp. 971-983
  • 2
    • 0027432418 scopus 로고
    • Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissue
    • Strong TV, Tagle DA, Valdes JM, et al. Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissue. Nat Genet 1993;5:259-265
    • (1993) Nat Genet , vol.5 , pp. 259-265
    • Strong, T.V.1    Tagle, D.A.2    Valdes, J.M.3
  • 3
    • 0026584524 scopus 로고
    • Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
    • Beal MF. Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann Neurol 1992;31:119-130
    • (1992) Ann Neurol , vol.31 , pp. 119-130
    • Beal, M.F.1
  • 4
    • 0026609559 scopus 로고
    • Alternative excitotoxic hypotheses
    • Albin RL, Greenamyre JT. Alternative excitotoxic hypotheses. Neurology 1992;42:733-738
    • (1992) Neurology , vol.42 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 5
    • 0029664992 scopus 로고    scopus 로고
    • Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH
    • Burke JR, Enghild JJ, Martin ME, et al. Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH. Nat Med 1996;2:347-350
    • (1996) Nat Med , vol.2 , pp. 347-350
    • Burke, J.R.1    Enghild, J.J.2    Martin, M.E.3
  • 6
    • 0027741301 scopus 로고
    • Evidence for an energy metabolism defect in Huntington's disease using localized proton spectroscopy
    • Jenkins B, Koroshetz W, Beal MF, Rosen B. Evidence for an energy metabolism defect in Huntington's disease using localized proton spectroscopy. Neurology 1993;43:2689-2695
    • (1993) Neurology , vol.43 , pp. 2689-2695
    • Jenkins, B.1    Koroshetz, W.2    Beal, M.F.3    Rosen, B.4
  • 7
    • 0014078148 scopus 로고
    • Rapid enzymatic measurement of blood lactate and pyruvate. Use and significance of metaphosphoric acid as a common precipitant
    • Marbach EP, Weil MH. Rapid enzymatic measurement of blood lactate and pyruvate. Use and significance of metaphosphoric acid as a common precipitant. Clin Chem 1967;13:314-325
    • (1967) Clin Chem , vol.13 , pp. 314-325
    • Marbach, E.P.1    Weil, M.H.2
  • 8
    • 0023115468 scopus 로고
    • Amino acid neurotransmitters in postmortem human brain analyzed by high performance liquid chromatography with electrochemical detection
    • Ellison DW, Beal MF, Martin JB. Amino acid neurotransmitters in postmortem human brain analyzed by high performance liquid chromatography with electrochemical detection. J Neurosci Methods 1987;19:305-315
    • (1987) J Neurosci Methods , vol.19 , pp. 305-315
    • Ellison, D.W.1    Beal, M.F.2    Martin, J.B.3
  • 9
    • 0000263890 scopus 로고
    • Extraneural metabolism in early Huntington's disease
    • O'Brien CF, Miller C, Goldblatt D, et al. Extraneural metabolism in early Huntington's disease. Ann Neurol 1990:28:300-301
    • (1990) Ann Neurol , vol.28 , pp. 300-301
    • O'Brien, C.F.1    Miller, C.2    Goldblatt, D.3
  • 10
    • 0026332133 scopus 로고
    • Factors associated with slow progression in Huntington's disease
    • Myers RH, Sax DS, Koroshetz WJ, et al. Factors associated with slow progression in Huntington's disease. Arch Neurol 1991;48:800-804
    • (1991) Arch Neurol , vol.48 , pp. 800-804
    • Myers, R.H.1    Sax, D.S.2    Koroshetz, W.J.3
  • 11
    • 0029875381 scopus 로고    scopus 로고
    • Mitochondrial defect in Huntington's disease caudate nucleus
    • Gu M, Gash MT, Mann VM, et al. Mitochondrial defect in Huntington's disease caudate nucleus. Ann Neurol 1996;39:385-389
    • (1996) Ann Neurol , vol.39 , pp. 385-389
    • Gu, M.1    Gash, M.T.2    Mann, V.M.3
  • 12
    • 0029118136 scopus 로고
    • Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates
    • Brouillet E, Hantraye P, Ferrante RJ, et al. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proc Natl Acad Sci USA 1995;92:7105-7109
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 7105-7109
    • Brouillet, E.1    Hantraye, P.2    Ferrante, R.J.3
  • 13
    • 0025730270 scopus 로고
    • 31P MRS) in neuromuscular disorders
    • 31P MRS) in neuromuscular disorders. Ann Neurol 1991;30:90-97
    • (1991) Ann Neurol , vol.30 , pp. 90-97
    • Argov, Z.1    Bank, W.J.2
  • 14
    • 0025968255 scopus 로고
    • In vivo muscle magnetic resonance spectroscopy in the clinical investigation of mitochondrial disease
    • Matthews PM, Allaire C, Shoubridge EA, et al. In vivo muscle magnetic resonance spectroscopy in the clinical investigation of mitochondrial disease. Neurology 1991;41:114-120
    • (1991) Neurology , vol.41 , pp. 114-120
    • Matthews, P.M.1    Allaire, C.2    Shoubridge, E.A.3
  • 15
    • 0029396976 scopus 로고
    • Generalized mitochondrial dysfunction in Parkinson's disease detected by magnetic resonance spectroscopy of muscle
    • Penn AMW, Roberts T, Hodder J, et al. Generalized mitochondrial dysfunction in Parkinson's disease detected by magnetic resonance spectroscopy of muscle. Neurology 1995;45:2097-2099
    • (1995) Neurology , vol.45 , pp. 2097-2099
    • Penn, A.M.W.1    Roberts, T.2    Hodder, J.3
  • 16
    • 0028170328 scopus 로고
    • 31P magnetic resonance spectroscopy study of mitochondrial function in skeletal muscle of patients with Parkinson's disease
    • 31P magnetic resonance spectroscopy study of mitochondrial function in skeletal muscle of patients with Parkinson's disease. J Neurol Sci 1994;125:77-81
    • (1994) J Neurol Sci , vol.125 , pp. 77-81
    • Taylor, D.J.1    Krige, D.2    Barnes, P.R.J.3
  • 17
    • 0026612942 scopus 로고
    • 31P NMR spectroscopy and ergometer exercise test as evidence for muscle oxidative performance improvement with coenzyme Q in mitochondrial myopathies
    • 31P NMR spectroscopy and ergometer exercise test as evidence for muscle oxidative performance improvement with coenzyme Q in mitochondrial myopathies. Neurology 1992;42:1203-1208
    • (1992) Neurology , vol.42 , pp. 1203-1208
    • Bendahan, D.1    Desnuelle, C.2    Vanuxem, D.3
  • 18
    • 0025123850 scopus 로고
    • The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lactic acidemia
    • Robinson BH, Glerum DM, Chow W, et al. The use of skin fibroblast cultures in the detection of respiratory chain defects in patients with lactic acidemia. Pediatr Res 1990;28:549-555
    • (1990) Pediatr Res , vol.28 , pp. 549-555
    • Robinson, B.H.1    Glerum, D.M.2    Chow, W.3
  • 19
    • 0025754439 scopus 로고
    • Marked reduction in CSF lactate and pyruvate levels after CoQ therapy in a patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS)
    • Abe K, Fujimura H, Nishikawa Y, et al. Marked reduction in CSF lactate and pyruvate levels after CoQ therapy in a patients with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Acta Neurol Scand 1991;83:356-359
    • (1991) Acta Neurol Scand , vol.83 , pp. 356-359
    • Abe, K.1    Fujimura, H.2    Nishikawa, Y.3
  • 20
    • 0023511584 scopus 로고
    • Increased lactate in cerebrospinal fluid from 7 siblings in a family with mitochondrial myopathy and cerebellar ataxia
    • Borud O, Torbergsen T, Mathiesen E. Increased lactate in cerebrospinal fluid from 7 siblings in a family with mitochondrial myopathy and cerebellar ataxia. J Inherit Metab Dis 1987;10:400
    • (1987) J Inherit Metab Dis , vol.10 , pp. 400
    • Borud, O.1    Torbergsen, T.2    Mathiesen, E.3
  • 21
    • 0030023259 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid lactate/pyruvate ratio in Machado-Joseph disease
    • Matsuishi T, Sakai T, Naito E, et al. Elevated cerebrospinal fluid lactate/pyruvate ratio in Machado-Joseph disease. Acta Neurol Scand 1996;93:72-75
    • (1996) Acta Neurol Scand , vol.93 , pp. 72-75
    • Matsuishi, T.1    Sakai, T.2    Naito, E.3
  • 22
    • 0014125293 scopus 로고
    • On changes in the composition of cerebrospinal fluid in the choreatic syndrome
    • Bruck J, Gerstenbrand F, Gnad H, et al. On changes in the composition of cerebrospinal fluid in the choreatic syndrome. J Neurol Sci 1967;5:257-265
    • (1967) J Neurol Sci , vol.5 , pp. 257-265
    • Bruck, J.1    Gerstenbrand, F.2    Gnad, H.3
  • 23
    • 0021678991 scopus 로고
    • Increased alanine aminotransferase activity in the Huntington's disease putamen
    • Carter CJ. Increased alanine aminotransferase activity in the Huntington's disease putamen. J Neurol Sci 1984:66:27-32
    • (1984) J Neurol Sci , vol.66 , pp. 27-32
    • Carter, C.J.1
  • 24
    • 0023114355 scopus 로고
    • Ethanolamine kinase activity in purified myelin of rat brain
    • Kunishita T, Vaswani KK, Morrow CR, et al. Ethanolamine kinase activity in purified myelin of rat brain. J Neurochem 1987;48:1-7
    • (1987) J Neurochem , vol.48 , pp. 1-7
    • Kunishita, T.1    Vaswani, K.K.2    Morrow, C.R.3
  • 25
    • 0023680684 scopus 로고
    • Role of mobility of redox components in the inner mitochondrial membrane
    • Lenaz G. Role of mobility of redox components in the inner mitochondrial membrane. J Membr Biol 1988;104:193-209
    • (1988) J Membr Biol , vol.104 , pp. 193-209
    • Lenaz, G.1
  • 26
    • 0020491098 scopus 로고
    • Lateral diffusion of ubiquinone during electron transfer in phospholipid- And ubiquinone-enriched mitochondrial membrane
    • Schneider H, Lemaster JJ, Hackembroek CR. Lateral diffusion of ubiquinone during electron transfer in phospholipid- and ubiquinone-enriched mitochondrial membrane. J Biol Chem 1982;257:10789-10793
    • (1982) J Biol Chem , vol.257 , pp. 10789-10793
    • Schneider, H.1    Lemaster, J.J.2    Hackembroek, C.R.3
  • 27
    • 0026879664 scopus 로고
    • An analysis of the role of coenzyme Q in free radical generation and as an antioxidant
    • Beyer RE. An analysis of the role of coenzyme Q in free radical generation and as an antioxidant. Biochem Cell Biol 1992;70:390-403
    • (1992) Biochem Cell Biol , vol.70 , pp. 390-403
    • Beyer, R.E.1
  • 28
    • 0023267038 scopus 로고
    • 10 in a patient with mitochondrial encephalomyopathy
    • 10 in a patient with mitochondrial encephalomyopathy. J Neurol 1987;2344:62-63
    • (1987) J Neurol , vol.2344 , pp. 62-63
    • Goda, S.1    Hamada, T.2    Ishimoto, S.3
  • 32
    • 0027336477 scopus 로고
    • 10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease
    • 10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43:884-890
    • (1993) Neurology , vol.43 , pp. 884-890
    • Matthews, P.M.1    Ford, B.2    Dandurand, R.J.3
  • 34
    • 0026764766 scopus 로고
    • Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration
    • Favit A, Nicoletti F, Scapagnini U, Canonico PL. Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration. J Cereb Blood Flow Metab 1992;12:638-645
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 638-645
    • Favit, A.1    Nicoletti, F.2    Scapagnini, U.3    Canonico, P.L.4
  • 35
    • 0028173480 scopus 로고
    • 10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate
    • 10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Ann Neurol 1994;36:882-888
    • (1994) Ann Neurol , vol.36 , pp. 882-888
    • Beal, M.F.1    Henshaw, D.R.2    Jenkins, B.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.