Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration

Journal of Neurochemistry

Volumn 78, Issue 5, 2001, Pages 1073-1082

  Levites, Yona ^a   Weinreb, Orly ^a   Maor, Gila ^b   Youdim, Moussa B H ^a,b   Mandel, Silvia ^a  

^a Eve Topf and USA National Parkinson Foundation   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

( ) Epigallocatechin 3 gallate; N methyl 4 phenyl 1,2,3,6 tetrahydropyridine; Neurodegenerative diseases; Oxidative stress; Parkinson's disease; Polyphenols

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; ANTIOXIDANT; CATALASE; DOPAMINE; EPIGALLOCATECHIN GALLATE; NEUROTOXIN; PLANT EXTRACT; POLYPHENOL; SUPEROXIDE DISMUTASE; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINE BRAIN LEVEL; DOPAMINERGIC NERVE CELL; DRUG PENETRATION; ENZYME ACTIVITY; ENZYME INHIBITION; IRON CHELATION; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA; TEA;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CATALASE; CATECHIN; DOPAMINE; DOPAMINE AGENTS; FLAVONOIDS; FREE RADICAL SCAVENGERS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED C57BL; MONOAMINE OXIDASE; MPTP POISONING; NERVE DEGENERATION; NEURONS; OXIDATIVE STRESS; PHENOLS; POLYMERS; RATS; SUPEROXIDE DISMUTASE; TEA; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 0034851553     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00490.x     Document Type: Article

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