Cu(II) potentiation of Alzheimer aβ neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction

Journal of Biological Chemistry

Volumn 274, Issue 52, 1999, Pages 37111-37116

  Huang, Xudong ^a   Cuajungco, Math P ^a   Atwood, Craig S ^a   Hartshorn, Mariana A ^a   Tyndall, Joel D A ^f   Hanson, Graeme R ^g   Stokes, Karen C ^c   Leopold, Michael ^c   Multhaup, Gerd ^b   Goldstein, Lee E ^a   Scarpa, Richard C ^a   Saunders, Aleister J ^a   Lim, James ^a   Moir, Robert D ^a   Glabe, Charles ^d   Bowden, Edmond F ^c   Masters, Colin L ^e   Fairlie, David P ^f   Tanzi, Rudolph E ^a   Bush, Ashley I ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f Ctr for Drug Design and Development   (Australia)

^g UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; COPPER; HYDROGEN PEROXIDE; METAL ION; PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; COLORIMETRY; CONTROLLED STUDY; CYCLIC POTENTIOMETRY; EMBRYO; NEUROTOXICITY; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

AMYLOID BETA-PROTEIN; ANIMALS; BRAIN; CELLS, CULTURED; COMPUTER SIMULATION; COPPER; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROGEN PEROXIDE; OXIDATION-REDUCTION; RATS;

ANIMALIA;

EID: 0033601338     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.52.37111     Document Type: Article

References (40)

1. Hensley, K., Hall, N., Subramanian, R., Cole, P., Harris, M., Aksenov, M., Aksenova, M., Gabbita, S. P., Wu, J. F., Carney, J. M., Lovell, M., Markesbery, W. E., and Butterfield, D. A. (1995) J. Neurochem. 65, 2146-2156
2. Smith, M. A., Hirai, K., Hsiao, K., Pappolla, M. A., Harris, P., Siedlak, S., Tabaton, M., and Perry, G. (1998) J. Neurochem. 70, 2212-2215
3. Hensley, K., Carney, J. M., Mattson, M. P., Aksenova, M., Harris, M., Wu, J. F., Floyd, R. A., and Butterfield, D. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 3270-3274
4. Mark, R. J., Lovell, M. A., Markesbery, W. R., Uchida, K., and Mattson, M. P. (1997) J. Neurochem. 68, 255-264
5. Behl, C., Davis, J. B., Lesley, R., and Schubert, D. (1994) Cell 77, 817-827
6. Huang, X., Atwood, C. S., Hartshorn, M. A., Multhaup, G., Goldstein, L. E., Scarpa, R. C., Cuajungco, M. P., Gray, D. N., Lim, J., Moir, R. D., Tanzi, R. E., and Bush, A. I. (1999) Biochemistry 38, 7609-7616
7. Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., and Markesbery, W. R. (1998) J. Neurol. Sci. 158, 47-52
8. Cherny, R. A., Legg, J. T., McLean, C. A., Fairlie, D., Huang, X., Atwood, C. S., Beyreuther, K., Tanzi, R. E., Masters, C. L., and Bush, A. I. (1999) J. Biol. Chem. 274, 23223-23228
9. Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D., and Younkin, S. (1996) Nat. Med. 2, 864-870
10. Vaughan, D. W., and Peters, A. (1981) J. Neuropathol. Exp. Neurol. 40, 472-487
11. Duff, K., Eckman, C., Zehr, C., Yu, X., Prada, C. M., Perez-tur, J., Hutton, M., Buee, L., Harigaya, Y., Yager, D., Morgan, D., Gordon, M. N., Holcomb, L., Refolo, L., Zenk, B., Hardy, J., and Younkin, S. (1996) Nature 383, 710-713
12. Shivers, B. D., Hilbich, C., Multhaup, G., Salbaum, M., Beyreuther, K., and Seeburg, P. H. (1988) EMBO J. 7, 1365-1370
13. Schubert, D., and Chevion, M. (1995) Biochem. Biophys. Res. Commun. 216, 702-707
14. Halliwell, B., and Gutteridge, J. M. C. (1984) Biochem. J. 219, 1-14
15. Stadtman, E. R., and Oliver, C. N. (1991) J. Biol. Chem. 266, 2005-2008
16. Bondy, S. C., Guo-Ross, S. X., and Truong, A. T. (1998) Brain Res. 799, 91-96
17. Atwood, C. S., Moir, R. D., Huang, X., Bacarra, N. M. E., Scarpa, R. C., Romano, D. M., Hartshorn, M. A., Tanzi, R. E., and Bush, A. I. (1998) J. Biol. Chem. 273, 12817-12826
18. Doré, S., Kar, S., and Quirion, R. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4772-4777
19. Landers, J. W., and Zak, B. (1958) Am. J. Clin. Pathol. 29, 590-592
20. Pilbrow, J. R., and Hanson, G. R. (1993) Methods Enzymol. 227, 330-353
21. Wang, D. M., and Hanson, G. R. (1995) J. Magn. Reson. A. 117, 1-8
22. Han, J., Yen, S., Han, G., and Han, P. (1996) Anal. Biochem. 234, 107-109
23. Sayre, L. M. (1996) Science 274, 1933-1934
24. Frausto da Silva, J. J. R., and Williams, R. J. P. (1991) The Biological Chemistry of the Elements, Clarendon Press, Oxford
25. Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K., and Muller-Hill, B. (1987) Nature 325, 733-736
26. Suzuki, N., Cheung, T. T., Cai, X. D., Odaka, A., Otvos L, Jr., Eckman, C., Golde, T. E., and Younkin, S. G. (1994) Science 264, 1336-1340
27. Mattson, M. P., Begley, J. G., Mark, R. J., and Furukawa, K. (1997) Brain Res. 771, 147-153
28. White, A. R., Bush, A. I., Beyreuther, K., Masters, C. L., and Cappai, R. (1999) J. Neurochem. 72, 2092-2098
29. Ito, N., Phillips, S. E., Stevens, C., Ogel, Z. B., McPherson, M. J., Keen, J. N., Yadav, K. D., and Knowles, P. F. (1991) Nature 350, 87-90
30. Barrow, C. J., and Zagorski, M. G. (1991) Science 253, 179-182
31. Hodgson, E. K., and Fridovich, I. (1975) Biochemistry 14, 5294-5299
32. Dikalov, S. I., Vitek, M. P., Maples, K. R., and Mason, R. P. (1999) J. Biol. Chem. 274, 9392-9399
33. Hartter, D. E., and Barnea, A. (1988) J. Biol. Chem. 263, 799-805
34. Rae, T. D., Schmidt, P. J., Pufahl, R. A., Culotta, V. C., and O'Halloran, T. V. (1999) Science 284, 805-808
35. Brown, D. R., Qin, K., Herms, J. W., Madlung, A., Manson, J., Strome, R., Fraser, P. E., Kruck, T., von Bohlen, A., Schulz-Schaeffer, W., Giese, A., Westaway, D., and Kretzschmar, H. (1997) Nature 390, 684-687
36. Deibel, M. A., Ehmann, W. D., and Markesbery, W. R. (1996) J. Neurol. Sci. 143, 137-142
37. Hershey, C. O., Hershey, L. A., Varnes, A., Vibhakar, S. D., Lavin, P., and Strain, W. H. (1983) Neurology 33, 1350-1353
38. Basun, H., Forssell, L. G., Wetterberg, L., and Winblad, B. (1991) J. Neural Transm. Park. Dis. Dement. Sect. 3, 231-258
39. Palmer, A. M., and Burns, M. A. (1994) Brain Res. 645, 338-342
40. Smith, M. A., Perry, G., Richey, P. L., Sayre, L. M., Anderson, V. E., Beal, M. F., and Kowall, N. (1996) Nature 382, 120-121