High-dose estradiol improves cognition for women with ad results of a randomized study

Neurology

Volumn 57, Issue 4, 2001, Pages 605-612

  Asthana, S ^a,b,c   Baker, L D ^a,b,c   Craft, S ^a,b,c   Stanczyk, F Z ^d   Veith, R C ^a,b,c   Raskind, M A ^a,b,c   Plymate, S R ^a,b,c  

^a VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^b Veterans Affairs Puget Sound Health Care System   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; SOMATOMEDIN C;

AGED; ALZHEIMER DISEASE; ARTICLE; ATTENTION; CLINICAL ARTICLE; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; FEMALE; HORMONE SUBSTITUTION; HUMAN; MEMORY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

EID: 0035964288     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.57.4.605     Document Type: Article

References (55)

1. Molecular basis of the neurodegenerative disorders
2. Follow-up 15 years after a geronto-psychiatric prevalence study: Conditions concerning death, cause of death, and life expectancy in relation to psychiatric diagnosis
3. Cognitive and neuroendocrine response to transdermal estrogen in postmenopausal women with Alzheimer's disease: Results of a placebocontrolled, double-blind, pilot study
4. Ovarian steroids and the brain: Implications for cognition and aging
5. The role of estrogen in the treatment of Alzheimer's disease
6. Estrogen therapy in postmenopausal women: Effects on cognitive function and dementia
7. Estrogen replacement therapy in older women: Comparisons between Alzheimer's disease cases and nondemented control subjects
8. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease: The Baltimore Longitudinal Study of Aging
9. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
10. Estrogen replacement therapy and Alzheimer's disease in the Italian Longitudinal Study on Aging
11. The molecular and neuroanatomical basis for estrogen effects in the central nervous system
12. Estrogen actions in the central nervous system
13. Cellular and molecular basis of estrogen's neuroprotection: Potential relevance for Alzheimer's disease
14. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
15. "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician
16. The association between measures of dementia and of senile change in the cerebral gray matter of elderly subjects
17. Introduction - The Brief Psychiatric Rating Scale (BPRS): Recent developments in ascertainment and scaling
18. The Clinician Interview-Based Impression (CIBI): A clinician's global change rating scale in Alzheimer's disease
19. Assessment of older people: Selfmaintaining and instrumental activities of daily living
20. A neuropsychological battery for epilepsy
21. Studies of interference in serial verbal reactions
22. A feature-integration theory of attention
23. Selective reminding for analysis of memory and learning
24. A standardized memory scale for clinical use
25. Translations of excerpts from Andre Rey's Psychological examination of traumatic encephalopathy and P.A Osterrieth's The complex figure copy test
26. Comparison of double- and singleisotope enzymatic derivative methods for measuring catecholamines in human plasma
27. Estrogen replacement therapy for the prevention and treatment of Alzheimer's disease
28. An effect of conjugated estrogen to cognitive impairment in women with senile dementia-Alzheimer's type: A placebo-controlled, double-blind study
29. Effects of estrogen on cognition, mood, and cerebral blood flow in AD
30. Estrogen for Alzheimer's disease in women: Randomized, double-blind, placebo-controlled trial
31. Estrogens in the pathogenesis and treatment of Alzheimer's disease in postmenopausal women
32. Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: A randomized controlled trial
33. Differences in pharmacokinetics and comparative bioavailability between Premarin and Estratab in healthy postmenopausal women
34. Use of estrogen in young girls with Turner syndrome: Effects on memory
35. Cognitive decline in women in relation to non-protein-bound oestradiol concentrations
36. Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognition
37. Pharmacology of estrogens
38. A comparison of circulating hormone levels in postmenopausal women receiving hormone replacement therapy
39. Effects of estrogen on memory function in surgically menopausal women
40. Variations in memory function and sex steroid hormones across the menstrual cycle
41. Neurobiological basis of behavior
42. Estradiol and progesterone regulate neuronal structure and synaptic connectivity in adult as well as developing brain
43. Effects of different oral estrogen formulations on insulin-like growth factor-I, growth hormone and growth hormone binding protein in postmenopausal women
44. Regulation of growth hormone and somatomedin-C secretion in postmenopausal women: Effect of physiological estrogen replacement therapy
45. Estradiol modulates insulin-like growth factor I receptors and binding proteins in neurons from the hypothalamus
46. Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation
47. Insulin and insulin-like growth factor-I regulate tau phosphorylation in cultured human neurons
48. Insulin-like growth factor receptors in the central nervous system: Phosphorylation events and cellular mediators of biological function
49. Evidence for the presence of specific receptors for insulin-like growth factors I (IGF-I) and 2 (IGF-2) and insulin throughout the adult human brain
50. Insulin-like growth factor-I and cognitive function in healthy older men
51. Transdermal 17 Β-estradiol combined with oral progestogen increases plasma levels of insulin-like growth factor-I in postmenopausal women
52. Lack of effect of transdermal estrogen on the growth hormone-insulin-like growth factor axis