Neuronal oxidative stress precedes amyloid-β deposition in down syndrome

Journal of Neuropathology and Experimental Neurology

Volumn 59, Issue 11, 2000, Pages 1011-1017

  Nunomura, Akihiko ^a,b   Perry, George ^a   Pappolla, Miguel A ^c   Friedland, Robert P ^a   Hirai, Keisuke ^a,d   Chiba, Shigeru ^b   Smith, Mark A ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ASAHIKAWA MEDICAL COLLEGE   (Japan)

^c UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

^d TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

8 hydroxyguanosine; Alzheimer disease; Amyloid ; Down syndrome; Nitric oxide; Nitrotyrosine; Oxidative damage

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYGUANINE; AMYLOID BETA PROTEIN; NUCLEIC ACID; PROTEIN;

ADOLESCENT; ADULT; AGE; AGED; AMYLOIDOSIS; ARTICLE; AUTOPSY; BRAIN LEVEL; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; DENSITY; DISEASE ASSOCIATION; DOWN SYNDROME; FEMALE; HUMAN; IMMUNOREACTIVITY; INFANT; MALE; NERVE CELL; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL;

EID: 0033758324     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/59.11.1011     Document Type: Article

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