메뉴 건너뛰기




Volumn 9, Issue 1, 1999, Pages 147-163

Oxidative stress in Huntington's disease

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; 8 HYDROXYDEOXYGUANOSINE; HEME OXYGENASE; HUNTINGTIN; MALONALDEHYDE; MUTANT PROTEIN;

EID: 0032903802     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.1999.tb00216.x     Document Type: Conference Paper
Times cited : (443)

References (105)
  • 1
    • 0025276132 scopus 로고
    • Striatal and nigral neuron subpopulations in rigid Huntington's disease: Implications for the functional anatomy of chorea and rigidity-akinesia
    • Albin RL, Reiner A, Anderson KD, Penney JB, Young AB (1990) Striatal and nigral neuron subpopulations in rigid Huntington's disease: Implications for the functional anatomy of chorea and rigidity-akinesia. Ann Neurol 27: 357-365
    • (1990) Ann Neurol , vol.27 , pp. 357-365
    • Albin, R.L.1    Reiner, A.2    Anderson, K.D.3    Penney, J.B.4    Young, A.B.5
  • 2
    • 0024450903 scopus 로고
    • The functional anatomy of basal ganglia disorders
    • Albin RL, Young AB, Penney JB (1989) The functional anatomy of basal ganglia disorders. Trends Neurosci 12: 366-375
    • (1989) Trends Neurosci , vol.12 , pp. 366-375
    • Albin, R.L.1    Young, A.B.2    Penney, J.B.3
  • 3
    • 0026609559 scopus 로고
    • Alternative excitotoxic hypotheses
    • Albin RL, Greenamyre JT (1992) Alternative excitotoxic hypotheses. Neurology 42: 733-738
    • (1992) Neurology , vol.42 , pp. 733-738
    • Albin, R.L.1    Greenamyre, J.T.2
  • 4
    • 0025321039 scopus 로고
    • Functional architecture of basal ganglia circuits: Neural substrates of parallel processing
    • Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 13: 266-271
    • (1990) Trends Neurosci , vol.13 , pp. 266-271
    • Alexander, G.E.1    Crutcher, M.D.2
  • 6
    • 0026584524 scopus 로고
    • Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illness?
    • Beal MF. (1992) Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illness? Ann Neurol 31: 119-130
    • (1992) Ann Neurol , vol.31 , pp. 119-130
    • Beal, M.F.1
  • 7
    • 0028077894 scopus 로고
    • Neurochemistry and toxin models in Huntington's disease
    • Beal MF (1994) Neurochemistry and toxin models in Huntington's disease. Curr Op Neurol 7: 542-547
    • (1994) Curr Op Neurol , vol.7 , pp. 542-547
    • Beal, M.F.1
  • 8
    • 0022446150 scopus 로고
    • Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid
    • Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, Martin JB (1986) Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature 321: 168-171
    • (1986) Nature , vol.321 , pp. 168-171
    • Beal, M.F.1    Kowall, N.W.2    Ellison, D.W.3    Mazurek, M.F.4    Swartz, K.J.5    Martin, J.B.6
  • 10
    • 0026347825 scopus 로고
    • Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism
    • Beal MF, Swartz KJ, Hyman BT, Storey E. Finn SF and Koroshetz W. (1991b) Aminooxyacetic acid results in excitotoxin lesions by a novel indirect mechanism. J Neurochem 57: 1068-1073
    • (1991) J Neurochem , vol.57 , pp. 1068-1073
    • Beal, M.F.1    Swartz, K.J.2    Hyman, B.T.3    Storey, E.4    Finn, S.F.5    Koroshetz, W.6
  • 12
    • 0027477946 scopus 로고
    • Do defects in mitochondrial energy metabolism underlie the pathology of neu rodegenerative diseases?
    • Beal MF, Hyman BT and Koroshetz W. (1993b) Do defects in mitochondrial energy metabolism underlie the pathology of neu rodegenerative diseases? Trends Neurosci 16: 125-131
    • (1993) Trends Neurosci , vol.16 , pp. 125-131
    • Beal, M.F.1    Hyman, B.T.2    Koroshetz, W.3
  • 13
    • 0028173480 scopus 로고
    • Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate
    • Beal MF, Henshaw DR, Jenkins BG, Rosen BR, Schulz JB. (1994) Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate. Ann Neurol 36: 882-888
    • (1994) Ann Neurol , vol.36 , pp. 882-888
    • Beal, M.F.1    Henshaw, D.R.2    Jenkins, B.G.3    Rosen, B.R.4    Schulz, J.B.5
  • 15
    • 0023679101 scopus 로고
    • Calcium transport and buffering in neurons
    • Blaustein MP (1988) Calcium transport and buffering in neurons. Trends Neurosci 11: 438-443
    • (1988) Trends Neurosci , vol.11 , pp. 438-443
    • Blaustein, M.P.1
  • 16
    • 0028952832 scopus 로고
    • Effect of peroxynitrite on the mitochondrial respiratory chain: Differential susceptibility of neurones and astrocytes in primary culture
    • Bolanos JP, Heales SJR, Land JM, Clark, JB (1995) Effect of peroxynitrite on the mitochondrial respiratory chain: Differential susceptibility of neurones and astrocytes in primary culture. J Neurochem 64: 1965-1972
    • (1995) J Neurochem , vol.64 , pp. 1965-1972
    • Bolanos, J.P.1    Heales, S.J.R.2    Land, J.M.3    Clark, J.B.4
  • 17
    • 0027082367 scopus 로고
    • Allocortical involvement in Huntington's disease
    • Braak H, Braak E (1992) Allocortical involvement in Huntington's disease. Neuropathol App Neurobiol 18: 539-547
    • (1992) Neuropathol App Neurobiol , vol.18 , pp. 539-547
    • Braak, H.1    Braak, E.2
  • 18
    • 0021883670 scopus 로고
    • Regional mitochondrial respiratory activity in Huntington's disease brain
    • Brennan WA, Bird ED, Aprille JR. (1985) Regional mitochondrial respiratory activity in Huntington's disease brain. J Neurochem 44: 1948-1950
    • (1985) J Neurochem , vol.44 , pp. 1948-1950
    • Brennan, W.A.1    Bird, E.D.2    Aprille, J.R.3
  • 21
  • 23
    • 0027939105 scopus 로고
    • Oxidative damage and mitochondrial dysfunction in neuro-degenerative diseases
    • Browne SE, Beal MF (1994) Oxidative damage and mitochondrial dysfunction in neuro-degenerative diseases. Biochem Soc Trans 22: 1002-1006
    • (1994) Biochem Soc Trans , vol.22 , pp. 1002-1006
    • Browne, S.E.1    Beal, M.F.2
  • 25
    • 0021917344 scopus 로고
    • Distribution of phosphate-activated glutaminase, succinic dehydrogenase, pyruvate dehydrogenase, and α-glutamyl transpeptidase in post-mortem brain from Huntington's disease and agonal cases
    • Butterworth J, Yates CM, Reynolds GP (1985) Distribution of phosphate-activated glutaminase, succinic dehydrogenase, pyruvate dehydrogenase, and α-glutamyl transpeptidase in post-mortem brain from Huntington's disease and agonal cases. J Neurol Sci 67: 161-171
    • (1985) J Neurol Sci , vol.67 , pp. 161-171
    • Butterworth, J.1    Yates, C.M.2    Reynolds, G.P.3
  • 26
    • 0032581167 scopus 로고    scopus 로고
    • Trinucleotide (CAG) repeat length is positively correlated with the degree of DNA fragmentation in Huntington's disease striatum
    • Butterworth NJ, Williams L, Bullock JY, Love DR, Faull RLM, Dragunow M, (1998) Trinucleotide (CAG) repeat length is positively correlated with the degree of DNA fragmentation in Huntington's disease striatum. Neurosci 87: 49-53
    • (1998) Neurosci , vol.87 , pp. 49-53
    • Butterworth, N.J.1    Williams, L.2    Bullock, J.Y.3    Love, D.R.4    Faull, R.L.M.5    Dragunow, M.6
  • 27
    • 0031978837 scopus 로고    scopus 로고
    • Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: Implications for ischemia and Huntington's disease
    • Calabresi P, Centonze D, Pisani A, Sancesario G, Gubellini P, Marfia GA, Bernardi G (1998) Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: implications for ischemia and Huntington's disease. Ann Neurol 43: 586-597
    • (1998) Ann Neurol , vol.43 , pp. 586-597
    • Calabresi, P.1    Centonze, D.2    Pisani, A.3    Sancesario, G.4    Gubellini, P.5    Marfia, G.A.6    Bernardi, G.7
  • 28
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi DW (1988) Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 11: 465-469
    • (1988) Trends Neurosci , vol.11 , pp. 465-469
    • Choi, D.W.1
  • 29
    • 0030812593 scopus 로고    scopus 로고
    • Transglutaminase-catalyzed inactivation of glyceralde-hyde 3-phosphate dehydrogenase and a-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length
    • Cooper AJL, Sheu K-FR, Burke JR, Onodera O, Strittmatter WJ, Roses AD, Blass JP. (1997) Transglutaminase-catalyzed inactivation of glyceralde-hyde 3-phosphate dehydrogenase and a-ketoglutarate dehydrogenase complex by polyglutamine domains of pathological length. Proc Nati Acad Sci USA. 94: 12604-12609
    • (1997) Proc Nati Acad Sci USA , vol.94 , pp. 12604-12609
    • Cooper, A.J.L.1    Sheu, K.-F.R.2    Burke, J.R.3    Onodera, O.4    Strittmatter, W.J.5    Roses, A.D.6    Blass, J.P.7
  • 31
    • 0023750525 scopus 로고
    • Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease
    • de la Monte SM, Vonsattel JP, Richardson Jr EP (1988) Morphometric demonstration of atrophic changes in the cerebral cortex, white matter, and neostriatum in Huntington's disease. J Neuropath Exp Neurol 47: 516-525
    • (1988) J Neuropath Exp Neurol , vol.47 , pp. 516-525
    • De La Monte, S.M.1    Vonsattel, J.P.2    Richardson Jr., E.P.3
  • 33
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DiFiglia M, Sapp E, Chase KO, Davies SW, Bates GP, Vonsattel J-P, Aronin N. (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277: 1990-1993
    • (1997) Science , vol.277 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.-P.6    Aronin, N.7
  • 34
    • 0030715040 scopus 로고    scopus 로고
    • Mapping frequencies of endogenous oxidative damage and the kinetic response to oxidative stress in a region of rat mtDNA
    • Driggers WJ, Holmquist GP, LeDoux SP, Wilson GL (1997) Mapping frequencies of endogenous oxidative damage and the kinetic response to oxidative stress in a region of rat mtDNA. Nucleic Acids Res 25: 4362-9
    • (1997) Nucleic Acids Res , vol.25 , pp. 4362-4369
    • Driggers, W.J.1    Holmquist, G.P.2    LeDoux, S.P.3    Wilson, G.L.4
  • 38
    • 0027933701 scopus 로고
    • +: Implications for neurodegeneration
    • +: implications for neurodegeneration. J Neurochem 63: 584-91
    • (1994) J Neurochem , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 41
    • 0010292306 scopus 로고    scopus 로고
    • Immunohistochemical localization of markers of oxidative injury in Huntington's disease
    • Ferrante RJ, Kowall NW, Hersch SM, Brown rh, Beal MF (1996) Immunohistochemical localization of markers of oxidative injury in Huntington's disease. Soc Neurosci 22: 92.5
    • (1996) Soc Neurosci , vol.22 , pp. 92-95
    • Ferrante, R.J.1    Kowall, N.W.2    Hersch, S.M.3    Brown, R.H.4    Beal, M.F.5
  • 42
    • 0025373259 scopus 로고
    • Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine
    • Fraga CG, Shigenaga MK, Park J-W, Degan P, Ames BN (1990) Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine. Proc Natl Acad Sci USA 87: 4533-4537
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4533-4537
    • Fraga, C.G.1    Shigenaga, M.K.2    Park, J.-W.3    Degan, P.4    Ames, B.N.5
  • 43
    • 0030069713 scopus 로고    scopus 로고
    • Relationship between trinucleotide repeats and neuropathological changes in Huntington's disease
    • Furtado S, Suchowersky O, Rewcastle B, Graham L, Klimek ML, Garber A. (1996) Relationship between trinucleotide repeats and neuropathological changes in Huntington's disease. Ann Neurol 39: 132-136
    • (1996) Ann Neurol , vol.39 , pp. 132-136
    • Furtado, S.1    Suchowersky, O.2    Rewcastle, B.3    Graham, L.4    Klimek, M.L.5    Garber, A.6
  • 44
    • 0017839485 scopus 로고
    • Juvenile Huntington chorea: Clinical, ultrastructural, and biochemical studies
    • Goebel HH, Heipertz R, Scholz W, Iqbal K, Tellez-Nagel I. (1978) Juvenile Huntington chorea: clinical, ultrastructural, and biochemical studies. Neurology 28: 23-31
    • (1978) Neurology , vol.28 , pp. 23-31
    • Goebel, H.H.1    Heipertz, R.2    Scholz, W.3    Iqbal, K.4    Tellez-Nagel, I.5
  • 46
    • 0021982117 scopus 로고
    • Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease
    • Graveland GA, Williams RS, DiFiglia M (1985) Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease. Science 227: 770-773 n
    • (1985) Science , vol.227
    • Graveland, G.A.1    Williams, R.S.2    DiFiglia, M.3
  • 48
    • 0027198567 scopus 로고
    • Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum
    • Greene JG, Porter RH, Eller RV, Greenamyre JT (1993) Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum. J Neurochem 61: 1151-1154
    • (1993) J Neurochem , vol.61 , pp. 1151-1154
    • Greene, J.G.1    Porter, R.H.2    Eller, R.V.3    Greenamyre, J.T.4
  • 51
    • 0027724925 scopus 로고
    • Functional aspects of creatine kinase in brain
    • Hemmer W, Wallimann T. (1993) Functional aspects of creatine kinase in brain. Dev Neurosci 15: 249-260
    • (1993) Dev Neurosci , vol.15 , pp. 249-260
    • Hemmer, W.1    Wallimann, T.2
  • 52
    • 0024561803 scopus 로고
    • Mitochondrial encephalomyopathy (MELAS): Pathological study and successful therapy withcoenzyme Q10 and idebenone
    • Ihara Y, Namba R, Kuroda S, Sato T, Shirabe T (1989) Mitochondrial encephalomyopathy (MELAS): pathological study and successful therapy withcoenzyme Q10 and idebenone. J Neurol Sci 90: 263-271
    • (1989) J Neurol Sci , vol.90 , pp. 263-271
    • Ihara, Y.1    Namba, R.2    Kuroda, S.3    Sato, T.4    Shirabe, T.5
  • 55
    • 0027741301 scopus 로고
    • Evidence for an energy metabolism defect in Huntington's disease using localized proton spectroscopy
    • Jenkins BG, Koroshetz W, Beal MF, Rosen B (1993) Evidence for an energy metabolism defect in Huntington's disease using localized proton spectroscopy. Neurology 43: 2689-2695
    • (1993) Neurology , vol.43 , pp. 2689-2695
    • Jenkins, B.G.1    Koroshetz, W.2    Beal, M.F.3    Rosen, B.4
  • 57
    • 0022993126 scopus 로고
    • Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity
    • Koh J-Y, Peters S, Choi DW (1986) Neurons containing NADPH-diaphorase are selectively resistant to quinolinate toxicity. Science 234: 73-76
    • (1986) Science , vol.234 , pp. 73-76
    • Koh, J.-Y.1    Peters, S.2    Choi, D.W.3
  • 61
    • 0025153344 scopus 로고
    • Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease
    • Kuwert T, Lange HW, Langer K-J, Herzog H, Aulich A, Feinendegen LE (1990) Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease. Brain 113: 1405-1423
    • (1990) Brain , vol.113 , pp. 1405-1423
    • Kuwert, T.1    Lange, H.W.2    Langer, K.-J.3    Herzog, H.4    Aulich, A.5    Feinendegen, L.E.6
  • 64
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane AW, Marzuki S, Ozawa T, Tanaka M (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1(8639): 642-645
    • (1989) Lancet , vol.1 , Issue.8639 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 65
    • 0026357457 scopus 로고
    • 3-nitropropionic acid: Exogenous animal neurotoxin and possible human striatal toxin
    • Ludolph AC, He F, Spencer PS, Hammerstad J, Sabri M. (1990) 3-nitropropionic acid: exogenous animal neurotoxin and possible human striatal toxin. Can. J. Neurol. Sci. 18: 492-498
    • (1990) Can. J. Neurol. Sci. , vol.18 , pp. 492-498
    • Ludolph, A.C.1    He, F.2    Spencer, P.S.3    Hammerstad, J.4    Sabri, M.5
  • 68
    • 0028861326 scopus 로고
    • Activity of pallidal neurons in the monkey during dyskinesia induced by injection of bicuculline in the external pallidum
    • Matsumara M, Tremblay L, Richard H, Filion M (1995) Activity of pallidal neurons in the monkey during dyskinesia induced by injection of bicuculline in the external pallidum. Neurosci 65: 59-70
    • (1995) Neurosci , vol.65 , pp. 59-70
    • Matsumara, M.1    Tremblay, L.2    Richard, H.3    Filion, M.4
  • 71
    • 0021870931 scopus 로고
    • The mechanism of glutamate-induced degeneration of cultured Huntington's disease and control fibroblasts
    • May PC, Gray PN (1985) The mechanism of glutamate-induced degeneration of cultured Huntington's disease and control fibroblasts. J Neurol Sci 70: 101-112
    • (1985) J Neurol Sci , vol.70 , pp. 101-112
    • May, P.C.1    Gray, P.N.2
  • 72
    • 85088084020 scopus 로고    scopus 로고
    • Polyglutamine containing proteins produce length-dependent aggregation and death in cultured cerebellar granule cells
    • Moulder KL, Onodera O, Burke J, Strittmatter WJ, Johnson Jr EM (1998) Polyglutamine containing proteins produce length-dependent aggregation and death in cultured cerebellar granule cells. Soc Neurosci 24: 379.5
    • (1998) Soc Neurosci , vol.24 , pp. 379-375
    • Moulder, K.L.1    Onodera, O.2    Burke, J.3    Strittmatter, W.J.4    Johnson Jr., E.M.5
  • 74
    • 0026774080 scopus 로고
    • Accumulation of cardiac lipofuscin depends on metabolic rate of mammals
    • Nakano M, Gotoh S (1992) Accumulation of cardiac lipofuscin depends on metabolic rate of mammals. J Gerontol 47: B126-129
    • (1992) J Gerontol , vol.47
    • Nakano, M.1    Gotoh, S.2
  • 75
    • 0030029427 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?
    • Nicoletti F, Bruno V, Copani A, Casabona G, Knopfel T (1996) Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders? Trends Neurosci 19: 267-271
    • (1996) Trends Neurosci , vol.19 , pp. 267-271
    • Nicoletti, F.1    Bruno, V.2    Copani, A.3    Casabona, G.4    Knopfel, T.5
  • 76
    • 0023895734 scopus 로고
    • Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced
    • Novelli A, Reilly JA, Lysko PG, Henneberry RC (1988) Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res 451: 205-212
    • (1988) Brain Res , vol.451 , pp. 205-212
    • Novelli, A.1    Reilly, J.A.2    Lysko, P.G.3    Henneberry, R.C.4
  • 79
    • 0028283985 scopus 로고
    • Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases
    • Perutz M, Johnson T, Suzuki M, Finch JT (1994) Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases. Proc Natl Acad Sci USA 91: 5355-5358
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5355-5358
    • Perutz, M.1    Johnson, T.2    Suzuki, M.3    Finch, J.T.4
  • 80
    • 0029072690 scopus 로고
    • Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models
    • Portera-Cailliau C, Hedreen JC, Price DL, Koliatsos VE (1995) Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models. J Neurosci 15: 3775-3787
    • (1995) J Neurosci , vol.15 , pp. 3775-3787
    • Portera-Cailliau, C.1    Hedreen, J.C.2    Price, D.L.3    Koliatsos, V.E.4
  • 82
    • 0028957560 scopus 로고
    • Reduced expression of preproenkephalin in striatal neurons from Huntington's disease patients
    • Richfield EK, Maguire-Zeiss KA, Cox C, Gilmore J, Voorn P (1995) Reduced expression of preproenkephalin in striatal neurons from Huntington's disease patients. Ann Neurol 37: 335-343
    • (1995) Ann Neurol , vol.37 , pp. 335-343
    • Richfield, E.K.1    Maguire-Zeiss, K.A.2    Cox, C.3    Gilmore, J.4    Voorn, P.5
  • 83
    • 0029089172 scopus 로고
    • When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
    • Ross CA (1995) When more is less: pathogenesis of glutamine repeat neurodegenerative diseases. Neuron 15:493-6
    • (1995) Neuron , vol.15 , pp. 493-496
    • Ross, C.A.1
  • 84
    • 0028873186 scopus 로고
    • Evidence fora preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis
    • Sapp E, Ge P, Aizawa H, Bird E, Penney J, Young AB, Vonsattel JP, DiFiglia M (1995) Evidence fora preferential loss of enkephalin immunoreactivity in the external globus pallidus in low grade Huntington's disease using high resolution image analysis. Neurosci 64: 397-404
    • (1995) Neurosci , vol.64 , pp. 397-404
    • Sapp, E.1    Ge, P.2    Aizawa, H.3    Bird, E.4    Penney, J.5    Young, A.B.6    Vonsattel, J.P.7    DiFiglia, M.8
  • 85
    • 0032475931 scopus 로고    scopus 로고
    • Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • Saudou F, Finkbeiner S, Devys D, Greenberg ME (1998) Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95: 55-66
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3    Greenberg, M.E.4
  • 88
    • 0030222107 scopus 로고    scopus 로고
    • Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity
    • Schulz JB, Henshaw DR, MacGarvey U and Beal MF. (1996a) Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity. Neurochem Intl 29: 167-171
    • (1996) Neurochem Intl , vol.29 , pp. 167-171
    • Schulz, J.B.1    Henshaw, D.R.2    MacGarvey, U.3    Beal, M.F.4
  • 89
    • 0029879056 scopus 로고    scopus 로고
    • Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: Implications for neurodegenerative diseases
    • Schulz JB, Matthews RT, Henshaw DR, Beal MF (1996b) Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases. Neurosci 71: 1043-1048
    • (1996) Neurosci , vol.71 , pp. 1043-1048
    • Schulz, J.B.1    Matthews, R.T.2    Henshaw, D.R.3    Beal, M.F.4
  • 91
    • 0024537069 scopus 로고
    • Effect of ambient oxygen concentration on lipofuscin accumulation in cultured rat heart myocytes - A novel in vitro model of lipofuscinogenesis
    • Sohal RS, Marzabadi MR, Galaris D, Brunk UT (1989) Effect of ambient oxygen concentration on lipofuscin accumulation in cultured rat heart myocytes - a novel in vitro model of lipofuscinogenesis. Free Radic Biol Med 6: 23-30
    • (1989) Free Radic Biol Med , vol.6 , pp. 23-30
    • Sohal, R.S.1    Marzabadi, M.R.2    Galaris, D.3    Brunk, U.T.4
  • 93
    • 0026795635 scopus 로고
    • Protein oxidation and aging
    • Stadtman ER (1992) Protein oxidation and aging. Science 257: 1220-1224
    • (1992) Science , vol.257 , pp. 1220-1224
    • Stadtman, E.R.1
  • 95
    • 0031889998 scopus 로고    scopus 로고
    • Lipofuscin: Mechanisms of formation and increase with age
    • Terman A, Brunk UT (1998) Lipofuscin: mechanisms of formation and increase with age. APMIS 106: 265-276
    • (1998) APMIS , vol.106 , pp. 265-276
    • Terman, A.1    Brunk, U.T.2
  • 97
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosome
    • The Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosome. Cell 72: 971-983
    • (1993) Cell , vol.72 , pp. 971-983
  • 98
    • 0025286039 scopus 로고
    • Relative sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum
    • Uemera Y, Kowall NW, Beal MF (1990) Relative sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum. Ann Neurol 27: 620-625
    • (1990) Ann Neurol , vol.27 , pp. 620-625
    • Uemera, Y.1    Kowall, N.W.2    Beal, M.F.3
  • 101
    • 0029895292 scopus 로고    scopus 로고
    • Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease
    • Weeks RA, Harding AE, Brooks DJ (1996) Striatal D1 and D2 dopamine receptor loss in asymptomatic mutation carriers of Huntington's disease. Ann Neurol 40: 49-54
    • (1996) Ann Neurol , vol.40 , pp. 49-54
    • Weeks, R.A.1    Harding, A.E.2    Brooks, D.J.3
  • 102
    • 0030613177 scopus 로고    scopus 로고
    • Huntingtin function is required for mouse brain development and is not impaired by the Huntington's disease CAG expansion mutation
    • White JK, Auerbach W, Duyao MP, Vonsattel J-P, Gusella JF, Joyner AL, MacDonald ME (1997) Huntingtin function is required for mouse brain development and is not impaired by the Huntington's disease CAG expansion mutation. Nat Genet 17: 404-410
    • (1997) Nat Genet , vol.17 , pp. 404-410
    • White, J.K.1    Auerbach, W.2    Duyao, M.P.3    Vonsattel, J.-P.4    Gusella, J.F.5    Joyner, A.L.6    MacDonald, M.E.7
  • 104
    • 0025768972 scopus 로고
    • Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition
    • Zeevalk GD, Nicklas WJ (1991) Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition. J Pharm Exp Ther 257: 870-878
    • (1991) J Pharm Exp Ther , vol.257 , pp. 870-878
    • Zeevalk, G.D.1    Nicklas, W.J.2
  • 105
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity
    • Zhang J, Dawson VL, Dawson TM, Snyder SH (1994) Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity. Science 263: 687-689
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.