Allosteric regulation of neuronal nitric oxide synthase by tetrahydrobiopterin and suppression of auto-damaging superoxide

Biochemical Journal

Volumn 346, Issue 3, 2000, Pages 767-776

  Kotsonis, Peter ^a,d   Fröhlich, Lothar G ^a   Shutenko, Zhanna V ^a   Horejsi, Renate ^b   Pfleiderer, Wolfgang ^c   Schmidt, Harald H H W ^a,e  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Medizinisch chemischen Institut und Pregl Laboratorium der Universitat Graz   (Austria)

^c UNIVERSITY OF KONSTANZ   (Germany)

^d Novatis Inst for Medical Sciences   (United Kingdom)

^e JUSTUS LIEBIG UNIVERSITY GIESSEN   (Germany)

Author keywords

H4Bip modulation; Monomerization; Nitric oxide synthase catalysis; Reactive oxygen species

Indexed keywords

ARGININE; BRAIN ENZYME; CITRULLINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SUPEROXIDE; TETRAHYDROBIOPTERIN;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SUBSTRATE COMPLEX; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; SWINE;

ALLOSTERIC REGULATION; ARGININE; BINDING SITES; BIOPTERIN; CATALYSIS; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INDICATORS AND REAGENTS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN STRUCTURE, QUATERNARY; SUPEROXIDES;

ANIMALIA; SUS SCROFA;

EID: 0034654022     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3460767     Document Type: Article

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