Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

Neurobiology of Aging

Volumn 22, Issue 2, 2001, Pages 187-194

  Lovell, Mark A ^a,b   Xie, Chengsong ^a   Markesbery, William R ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Alzheimer's disease; Brain; Free radicals; Lipid peroxidation; Neuronal cultures; Neurotoxin

Indexed keywords

4 HYDROXYNONENAL; ACROLEIN; ALPHA TOCOPHEROL; CALCIUM; GLUTATHIONE; ISOPROSTANE; LIPID; POLYUNSATURATED FATTY ACID;

AGED; ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; LIPID PEROXIDATION; MALE; NERVE CELL CULTURE; NERVE CELL DEGENERATION; NEUROFIBRILLARY TANGLE; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RAT; SUBICULUM;

ACROLEIN; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ANIMALS; CALCIUM; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FREE RADICALS; HIPPOCAMPUS; HUMANS; LIPID PEROXIDATION; MALE; NEURONS; RATS;

EID: 0035112495     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(00)00235-9     Document Type: Article

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