Protective effect of a novel free radical scavenger, OPC-14117, on wobbler mouse motor neuron disease

Journal of Neuroscience Research

Volumn 48, Issue 1, 1997, Pages 63-70

  Abe, K ^a   Morita, S ^b   Kikuchi, T ^b   Itoyama, Y ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

free radical; motor neuron death; OPC 14117; wobbler mice

Indexed keywords

N (7 HYDROXY 2,2,4,6 TETRAMETHYL 1 INDANYL) 4 (3 METHOXYPHENYL) 1 PIPERAZINEACETAMIDE; SCAVENGER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; FORELIMB; HISTOPATHOLOGY; MORTALITY; MOTOR ACTIVITY; MOTOR NEURON DISEASE; MOUSE; MUSCLE WEAKNESS; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SURVIVAL RATE;

ALDEHYDES; ANIMALS; BEHAVIOR, ANIMAL; CROSS-LINKING REAGENTS; DISEASE MODELS, ANIMAL; FEMALE; FREE RADICAL SCAVENGERS; HETEROZYGOTE; HOMOZYGOTE; INDANS; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MICE; MICE, NEUROLOGIC MUTANTS; MOTOR NEURON DISEASE; NEUROPROTECTIVE AGENTS; PIPERAZINES; PREGNANCY; SPINAL CORD; SURVIVAL ANALYSIS;

EID: 0030887358     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19970401)48:1<63::AID-JNR6>3.0.CO;2-C     Document Type: Article

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