Regulation of immunoglobulin class-switch recombination: Choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair

Advances in Immunology

Volumn 122, Issue , 2014, Pages 1-57

  Matthews, Allysia J ^a,b   Zheng, Simin ^a,b   DiMenna, Lauren J ^a,b   Chaudhuri, Jayanta ^a,b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Weill Cornell Graduate School of Biomedical Sciences   (United States)

Author keywords

Activation induced deaminase; Class switch recombination; Induced pluripotency; Lymphomagenesis

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN 14 3 3; PROTEIN GANP; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; URACIL;

ARTICLE; B CELL LYMPHOMA; BINDING AFFINITY; CARCINOGENESIS; CHROMOSOME PAIRING; COMPLEMENTARITY DETERMINING REGION; DEAMINATION; DNA END JOINING REPAIR; DNA MODIFICATION; DNA REPAIR; DNA TRANSCRIPTION; ENZYME LOCALIZATION; ENZYME PHOSPHORYLATION; EPIGENETICS; GENE AMPLIFICATION; GENE INDUCTION; GENE LOCUS; GENE REARRANGEMENT; GENE TARGETING; GENE TRANSLOCATION; GERM LINE; HUMAN; NONHUMAN; PLURIPOTENT STEM CELL; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA EDITING; SINGLE STRANDED DNA BREAK; SOMATIC HYPERMUTATION; TRANSCRIPTION REGULATION; VDJ RECOMBINATION;

ACTIVATION-INDUCED DEAMINASE; CLASS-SWITCH RECOMBINATION; INDUCED PLURIPOTENCY; LYMPHOMAGENESIS;

ANIMALS; B-LYMPHOCYTES; CYTIDINE DEAMINASE; DNA DAMAGE; DNA REPAIR; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; RECOMBINATION, GENETIC; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC; V(D)J RECOMBINATION;

EID: 84893411589     PISSN: 00652776     EISSN: 15578445     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800267-4.00001-8     Document Type: Chapter

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