Both CpG methylation and activation-induced deaminase are required for the fragility of the human bcl-2 major breakpoint region: Implications for the timing of the breaks in the t(14;18) translocation

Molecular and Cellular Biology

Volumn 33, Issue 5, 2013, Pages 947-957

  Cui, Xiaoping ^a   Lu, Zhengfei ^a   Kurosawa, Aya ^b   Klemm, Lars ^c   Bagshaw, Andrew T ^d   Tsai, Albert G ^a   Gemmell, Neil ^d   Müschen, Markus ^a,c   Adachi, Noritaka ^b   Hsieh, Chih Lin ^a   Lieber, Michael R ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; PHOSPHODIESTERASE; PROTEIN BCL 2; RAG1 PROTEIN;

ARTICLE; CELL LINE; CHROMOSOME 14; CHROMOSOME 18; CPG ISLAND; DNA END JOINING REPAIR; DNA METHYLATION; DOUBLE STRANDED DNA BREAK; GENE TRANSLOCATION; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE;

B-LYMPHOCYTES; CELL LINE; CHROMOSOME BREAKPOINTS; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 18; CPG ISLANDS; CYTIDINE DEAMINASE; DNA; DNA METHYLATION; GENE KNOCKOUT TECHNIQUES; GENES, BCL-2; HOMEODOMAIN PROTEINS; HUMANS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSLOCATION, GENETIC;

EID: 84873297583     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01436-12     Document Type: Article

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