Uracil DNA glyclosylase activity is dispensable for immunoglobulin class switch

Science

Volumn 305, Issue 5687, 2004, Pages 1160-1163

  Begum, Nasim A ^a   Kinoshita, Kazuo ^a   Kakazu, Naoki ^b   Muramatsu, Masamichi ^a   Nagaoka, Hitoshi ^a   Shinkura, Reiko ^a   Biniskiewicz, Detlev ^c   Boyer, Laurie A ^c   Jaenisch, Rudolf ^c   Honjo, Tasuku ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINATION; CELLS; ENZYMES; RNA;

CLASS SWITCH RECOMBINATION (CSR); DEAMINATION;

DNA;

CYTIDINE DEAMINASE; CYTOSINE; DNA; DNA GLYCOSYLTRANSFERASE; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; URACIL; URACIL DNA GLYCOSYLTRANSFERASE; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); URACIL DNA GLYCOSIDASE; URACIL DNA GLYCOSYLASE INHIBITOR, VIRUS; URACIL-DNA GLYCOSYLASE INHIBITOR, VIRUS; VIRUS PROTEIN;

CELLS AND CELL COMPONENTS; DNA;

ARTICLE; DEAMINATION; DNA DETERMINATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE LOCUS; GENE MUTATION; GENE REARRANGEMENT; GENETIC RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; ANIMAL; B LYMPHOCYTE; DNA REPAIR; DRUG ANTAGONISM; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; IMMUNOGLOBULIN GENE; IMMUNOLOGY; METABOLISM; MOUSE; MUTATION; PHYSIOLOGY; SERODIAGNOSIS; TUMOR CELL LINE;

ANIMALS; B-LYMPHOCYTES; CELL LINE, TUMOR; CYTIDINE DEAMINASE; DNA; DNA GLYCOSYLASES; DNA REPAIR; GENES, IMMUNOGLOBULIN; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN SWITCH REGION; MICE; MUTATION; PRECIPITIN TESTS; RECOMBINATION, GENETIC; TRANSFECTION; URACIL; URACIL-DNA GLYCOSIDASE; VIRAL PROTEINS;

EID: 4344560868     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1098444     Document Type: Article

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