AID mutant analyses indicate requirement for class-switch-specific cofactors

Nature Immunology

Volumn 4, Issue 9, 2003, Pages 843-848

  Ta, Van Thanh ^d   Nagaoka, Hitoshi ^d   Catalan, Nadia ^a   Durandy, Anne ^a   Fischer, Alain ^a   Imai, Kohsuke ^a,c   Nonoyama, Shigeaki ^b,c   Tashiro, Junko ^d   Ikegawa, Masaya ^d   Ito, Satomi ^d   Kinoshita, Kazuo ^d   Muramatsu, Masamichi ^d   Honjo, Tasuku ^d  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; MUTANT PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; GENE ACTIVITY; GENE FUNCTION; GENE INSERTION; GENE LOSS; GENE REARRANGEMENT; GENETIC CONSERVATION; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; MOLECULAR EVOLUTION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SOMATIC HYPERMUTATION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; CYTIDINE DEAMINASE; DNA; ESCHERICHIA COLI; HUMANS; IMMUNE COMPLEX DISEASES; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN M; IMMUNOGLOBULIN SWITCH REGION; MICE; MOLECULAR SEQUENCE DATA; POINT MUTATION; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; TRANSFECTION;

EID: 0041381361     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni964     Document Type: Article

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